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Reduced Perinatal Proteobacteria Exposure Linked to Childhood Wheezing

Reduced Perinatal Proteobacteria Exposure Linked to Childhood Wheezing

Lower exposure to Proteobacteria in umbilical cord serum was associated with an increased risk for childhood wheezing.

Delabeling Patients as Beta-Lactam Allergic Requires Record Updates

Delabeling Patients as Beta-Lactam Allergic Requires Record Updates

Changes in allergy records were suggested by the allergy service consult for 62% of the patients.

Additional Symjepi Dosage Strength Approved for Anaphylaxis Treatment

Additional Symjepi Dosage Strength Approved for Anaphylaxis Treatment

Both doses will be supplied in single-dose, prefilled syringes for manual injection.

Pest Allergies in Urban Adolescents Exacerbate Poorly Controlled Asthma

Pest Allergies in Urban Adolescents Exacerbate Poorly Controlled Asthma

Cockroach and mouse allergies were most often associated with poorly controlled asthma and exacerbations in urban adolescents.

Allergy, But Not Asthma, Risk Increased in Children of East Asian Descent

Allergy, But Not Asthma, Risk Increased in Children of East Asian Descent

Children of East Asian-born parents had an increased risk for allergic rhinitis and aeroallergen sensitization compared with children of Caucasian ancestry.

PUFAs Inversely Associated With Asthma in Preschool Children

PUFAs Inversely Associated With Asthma in Preschool Children

Total omega-3 and omega-6 plasma polyunsaturated fatty acids relative abundances were significantly inversely correlated with asthma/recurrent wheeze and allergic sensitization.

Relationship Between Atopic Disorders May Be Age Dependent

Relationship Between Atopic Disorders May Be Age Dependent

Although allergic sensitization and hay fever rates increased as children grew older, the rates of asthma dropped.

Addition of High-Dose Guaifenesin Benefits Patient With Chronic Respiratory Conditions

Addition of High-Dose Guaifenesin Benefits Patient With Chronic Respiratory Conditions

According to the report, the patient complained of a non-productive cough, accumulation of mucus, and post-nasal drip and requested a thorough assessment of her medical conditions.

Asthma Control Not Improved With School-Supervised Inhaled Corticosteroid Use

Asthma Control Not Improved With School-Supervised Inhaled Corticosteroid Use

In a population of primarily Latino children from low-income households, a program of school-supervised use of once-daily inhaled corticosteroids failed to improve asthma control.

Veta Smart Case, App for Epinephrine Auto-Injectors Now Available

Veta Smart Case, App for Epinephrine Auto-Injectors Now Available

The Smart Case includes electronics and sensors to monitor the proximity, temperature, presence and removal, and expiration of auto-injectors.

Walgreens to Offer Auvi-Q Nationwide in an Effort to Address Epinephrine Supply Issues

Walgreens to Offer Auvi-Q Nationwide in an Effort to Address Epinephrine Supply Issues

This effort is in response to epinephrine auto-injector supply issues reported by manufacturers to the Food and Drug Administration (FDA).

Prevalence of Asthma Exacerbations That Also Meet Anaphylaxis Criteria

Prevalence of Asthma Exacerbations That Also Meet Anaphylaxis Criteria

A total of 8% of patients with asthma exacerbations met the criteria for diagnosing anaphylaxis, with 3.4% having likely experienced anaphylaxis.

Asthma Medicine Recalled Due to Tablet Mix-Up That May Pose Safety Risk

Asthma Medicine Recalled Due to Tablet Mix-Up That May Pose Safety Risk

The risk of a mixing-up the treatments is especially high for pregnant women, says the Food and Drug Administration (FDA), as losartan is indicated to treat high blood pressure and could harm or kill a fetus.

Novel Epinephrine Nasal Spray for Anaphylaxis Gets Fast Tracked by FDA

Novel Epinephrine Nasal Spray for Anaphylaxis Gets Fast Tracked by FDA

The bioavailability of the novel epinephrine nasal spray also proved similar to that of intramuscular injection with EpiPen 0.3mg injection.

Single-Administration Treatment for Hereditary Angioedema Gets Orphan Drug Status

Single-Administration Treatment for Hereditary Angioedema Gets Orphan Drug Status

ADVM-053 is being developed as a single‑administration treatment that could potentially provide sustained levels of the C1 esterase inhibitor protein, which may prevent breakthrough angioedema attacks.

First-of-its-Kind Therapy Approved to Prevent Hereditary Angioedema Attacks

First-of-its-Kind Therapy Approved to Prevent Hereditary Angioedema Attacks

The approval was based on data from 4 clinical trials, including the 26-week Phase 3 HELP (Hereditary Angioedema Long-Term Prophylaxis) study that enrolled 125 patients with HAE aged ≥12 years.

Mucosal Response to Nasal Bacteria Could Affect Chronic Rhinosinusitis

Mucosal Response to Nasal Bacteria Could Affect Chronic Rhinosinusitis

Haemophilus influenzae, Staphylococcus aureus, and Streptococcus pyogenes were found in approximately one-fifth of isolated IgE antibodies via plasmablasts residing in nasal polyps.

FDA Extends Expiration Date for Certain Lots of EpiPen

FDA Extends Expiration Date for Certain Lots of EpiPen

This date modification beyond the approved 20-month shelf life was based an FDA review of product stability data submitted by Mylan.

Asthma and Allergic Rhinitis May Be Risk Factors for Migraine in Adolescents

Asthma and Allergic Rhinitis May Be Risk Factors for Migraine in Adolescents

Adolescents who have asthma or allergic rhinitis may be at higher risk for developing migraine.

First Generic Version of EpiPen Gets FDA Approval

First Generic Version of EpiPen Gets FDA Approval

Unlike other generic approvals, epinephrine auto-injectors are considered "combination products" because they consist of both a drug and a device, making the approval process more challenging.

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