An increase in atheroma burden and plaques with less stable features demonstrated an association with immunoglobulin E to α-Gal.
Cytokines produced by mitogen-stimulated immune cells from pregnant women without asthma were shown to be associated with the development of asthma in their children.
Respiratory symptoms were more common in older children compared with infants who presented with food-induced anaphylaxis.
In addition to respiratory sensitivity to aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), patients with AERD oftentimes experience an additional allergic reaction when drinking alcohol.
Clinically meaningful benefits were seen in patients with chronic rhinosinusitis, but the treatment effect was imprecise.
Lone star tick is most common in the South, but may be spreading to new areas.
The eFlow® nebulizer delivered CDP7766 without evidence of degradation, loss of potency, aggregation, or formation of particulates in a model of asthma in cynomolgus macaques.
Many patients with moderate to severe atopic dermatitis have inadequate disease control.
Bronchiectasis-associated genera included Aspergillus, Cryptococcus, Clavispora, Botrytis, and Alternaria.
Children with the early-onset persistent bronchial hyperresponsiveness phenotype had the highest blood eosinophil count and total serum IgE levels as well as sensitization rates.
The approval was based on data from a randomized, single-blind, multicenter, dose-ranging, crossover study which evaluated the safety and efficacy of Cinryze in 12 pediatric patients (7 to 11 years old).
The mean rate of exacerbations declined significantly after 1 year of subcutaneous immunotherapy in children with moderate to severe allergic asthma exacerbations.
Allergic rhinitis also had a negative effect on daily functioning, sleep, school productivity, and academic performance.
Most adults (52%) reported that an EAI was not used during their most severe reaction, even though it would have been beneficial, 45% said they didn't have it with them at the time.
Because determining an appropriate treatment plan for a patient depends on the subtype of the disease, it is imperative for providers to know and understand the underlying mechanisms of CRS as well as the components included in a medical evaluation of a patient.
A nasal immune-response pattern characterized by lower non-interferon antiviral immune response mediators and higher type 2 and type 17 cytokines was significantly associated with recurrent wheeze at 1 year.
The pharmacokinetics trial, which included 60 participants with seasonal allergies, also demonstrated rapid drug absorption with the intranasal spray.
Adenoidectomy and tonsillectomy in children by age 9 were associated with higher long-term risks for respiratory, infectious, and allergic diseases.
Vitamin D supplementation appears to reduce the recurrent wheezing by 12 months of age in black infants born prematurely.
Fluticasone Propionate Nasal Spray is a corticosteroid indicated for the management of the nasal symptoms of perennial nonallergic rhinitis in adults and pediatric patients aged 4 years and older.
Researchers developed a predictive algorithm to identify individuals with a higher risk for severe reactions to the standardized peanut oral food challenge.
Montelukast improved symptoms in a significant proportion of individuals with angioedema-predominant chronic spontaneous urticaria.
Many parents feel additional food labeling, allergy education, and stocking of epinephrine are needed.
The pattern of laryngeal motor dysfunction and the prevalence and severity of laryngeal hypersensitivity in individuals with chronic cough were similar to that observed in individuals with vocal cord dysfunction and muscle tension dysphonia.
A strong dose-response relation was seen with atopic eczema severity.
Researchers have developed a novel algorithm to identify hypersensitivity pneumonitis.
Nasal beclomethasone dipropionate was more effective in improving nasal patency and cytology as well as quality of life compared with cetirizine in children with perennial allergic rhinitis.
Physiological lipids in the products restored skin barrier function and hydration.
Potential risk factors for eosinophilic esophagitis include antibiotic use in infancy and behaviors such as smoking and alcohol intake.
Intermittent supply constraints due to manufacturing delays from Mylan's manufacturing partner, Meridian Medical Technologies, have resulted in varying supply levels.