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COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

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COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Patients with asthma or chronic obstructive pulmonary disease have especially high rates of nonadherence, even in comparison with other chronic diseases.

Asthma Development in Early Childhood May Hinge on Early Life Stress

Asthma Development in Early Childhood May Hinge on Early Life Stress

Prenatal and early life stress, including societal stress, have been implicated in the development of asthma and other allergic diseases in children.

Volatile Organic Compound Analysis in Pediatric Asthma: A New Clinical Tool

Volatile Organic Compound Analysis in Pediatric Asthma: A New Clinical Tool

Analyzing volatile organic compounds in pediatric patients with asthma shows promise for disease diagnosis and management.

Precision Medicine May Pave the Way for Better Treatment in Asthma, COPD

Precision Medicine May Pave the Way for Better Treatment in Asthma, COPD

At a research seminar held by the European Respiratory Society in February 2017, a group of investigators discussed how precision medicine may improve treatment in asthma and COPD.

Role of E-Cigarettes in Asthma Development and Exacerbation

Role of E-Cigarettes in Asthma Development and Exacerbation

Smokers with asthma have been encouraged to switch from conventional to electronic cigarettes, but the latter may still cause respiratory damage.

The Potential Pitfalls of Machine Learning Algorithms in Medicine

The Potential Pitfalls of Machine Learning Algorithms in Medicine

The ability of machine learning programs to diagnose medical conditions and predict outcomes is discussed in an opinion article.

Asthma Control With Mobile Health Initiatives

Asthma Control With Mobile Health Initiatives

Mobile devices may help patients with asthma better manage and control their disease.

Asthma Management During Pregnancy: How to Benefit Both Mothers and Infants

Asthma Management During Pregnancy: How to Benefit Both Mothers and Infants

Although some pregnant women discontinue their asthma medications for fear of fetal drug toxicity, they may be putting their babies at greater risk.

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Fewer Asthma Exacerbations With LABA Plus Inhaled Glucocorticoid

Fewer Asthma Exacerbations With LABA Plus Inhaled Glucocorticoid

Combination therapy with a long-acting β2-agonist plus an inhaled glucocorticoid for asthma was not associated with a significantly higher risk for serious asthma-related events compared with an inhaled glucocorticoid alone.

Childhood Respiratory Risk Factor Profiles Predict Lung Function, COPD

Childhood Respiratory Risk Factor Profiles Predict Lung Function, COPD

Frequent asthma, bronchitis, allergy demonstrated the strongest association with , lower FEV1, lower FEV1/forced vital capacity, and increased risk for COPD.

Cytokine Profiles of Pregnant Women Predict Asthma in Children

Cytokine Profiles of Pregnant Women Predict Asthma in Children

Cytokines produced by mitogen-stimulated immune cells from pregnant women without asthma were shown to be associated with the development of asthma in their children.

CDC: Wildfire Smoke Poses Health Risks

CDC: Wildfire Smoke Poses Health Risks

The US Centers for Disease Control offers steps to minimize exposure to wildfire smoke, particularly for those with chronic conditions.

Free Vitamin D3 Inferior to Total Concentrations in Predicting Asthma Response

Free Vitamin D3 Inferior to Total Concentrations in Predicting Asthma Response

No associations were found between free concentration vitamin D3 levels and treatment failure or exacerbation rates in adults with asthma

Inhaled IL-13 Monoclonal Antibody Inhibits IL-13 in Animal Asthma Model

Inhaled IL-13 Monoclonal Antibody Inhibits IL-13 in Animal Asthma Model

The eFlow® nebulizer delivered CDP7766 without evidence of degradation, loss of potency, aggregation, or formation of particulates in a model of asthma in cynomolgus macaques.

Anti-IL-5 Therapy Eligibility Characteristics Examined in Adult-Onset Asthma

Anti-IL-5 Therapy Eligibility Characteristics Examined in Adult-Onset Asthma

Patients with severe asthma were more often current smokers at diagnosis and had higher body mass index at follow-up compared with patients with nonsevere asthma and anti-IL-5 therapy-eligible asthma.

Patient Engagement in Asthma Treatment Plans May Improve Quality of Life

Patient Engagement in Asthma Treatment Plans May Improve Quality of Life

Older adults with asthma and a greater desire for involvement in decision making have higher asthma-related quality of life.

Obstructive Sleep Apnea in Asthma: Gaining Control by Losing Weight

Obstructive Sleep Apnea in Asthma: Gaining Control by Losing Weight

Poor control of asthma and obstructive sleep apnea can feed off one another, according to Michelle Zeidler, MD, pulmonologist at the University of California, Los Angeles, and director of the UCLA Sleep Fellowship Program.

Asthma Risk Increased With Early-Onset Persistent Bronchial Hyperresponsiveness

Asthma Risk Increased With Early-Onset Persistent Bronchial Hyperresponsiveness

Children with the early-onset persistent bronchial hyperresponsiveness phenotype had the highest blood eosinophil count and total serum IgE levels as well as sensitization rates.

Subcutaneous Immunotherapy Shows Promise for Allergic Asthma Exacerbations

Subcutaneous Immunotherapy Shows Promise for Allergic Asthma Exacerbations

The mean rate of exacerbations declined significantly after 1 year of subcutaneous immunotherapy in children with moderate to severe allergic asthma exacerbations.

Asthma Exacerbation, Treatment Failure Prevention During Step-Down Therapy

Asthma Exacerbation, Treatment Failure Prevention During Step-Down Therapy

A hospital emergency department visit in the prior year was associated with subsequent asthma treatment failure.

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory pathogens were associated with an increased risk for treatment failure in children with asthma exacerbations.

Tralokinumab Ineffective for Eosinophilic Airway Inflammation in Asthma

Tralokinumab Ineffective for Eosinophilic Airway Inflammation in Asthma

Tralokinumab did not have a significant effect on eosinophilic airway inflammation in moderate to severe asthma that was inadequately controlled on inhaled corticosteroids.

Viruses not linked to asthma exacerbation severity

Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure.

Immune-Response Cluster in Infant Respiratory Syncytial Virus Linked With Recurrent Wheeze

Immune-Response Cluster in Infant Respiratory Syncytial Virus Linked With Recurrent Wheeze

A nasal immune-response pattern characterized by lower non-interferon antiviral immune response mediators and higher type 2 and type 17 cytokines was significantly associated with recurrent wheeze at 1 year.

Budesonide-formoterol as needed superior to terbutaline in mild asthma: The SYGMA trial

In patients with mild asthma, use of the inhaled combined corticosteroid and beta agonist budesonide-formoterol as needed was superior to terbutaline as needed with respect to electronically recorded weeks of well-controlled asthma.

Various Perinatal Risks Associated With Maternal Asthma Diagnosis

Various Perinatal Risks Associated With Maternal Asthma Diagnosis

Women with a diagnosis of asthma may have a higher risk for preterm birth, and their infants may have an increased risk for perinatal mortality, low birth weight, fetal growth restriction, and asphyxia.

Omalizumab Inhibits Respiratory Reactions During Aspirin Desensitization

Omalizumab Inhibits Respiratory Reactions During Aspirin Desensitization

In patients with aspirin exacerbated respiratory disease, treatment with omalizumab resulted in "clinically silent" aspirin desensitization.

Asthma Exacerbation Risk With As-Needed Budesonide-Formoterol vs Maintenance Budesonide

Asthma Exacerbation Risk With As-Needed Budesonide-Formoterol vs Maintenance Budesonide

Budesonide-formoterol as needed was not inferior compared with budesonide maintenance therapy in terms of severe asthma exacerbation rates, but may be inferior for controlling symptoms.

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