Asthma

Pulmonary Symptoms With GERD in Infants May Increase Asthma Risk

Pulmonary Symptoms With GERD in Infants May Increase Asthma Risk

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Infants who presented with pulmonary symptoms when diagnosed with gastroesophageal reflux disease had a higher incidence of early onset asthma compared with infants who did not have pulmonary symptoms.

Lung Function Improved With Dupilumab in Adolescents With Asthma

Lung Function Improved With Dupilumab in Adolescents With Asthma

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Adolescents with asthma treated with dupilumab experienced significant improvements in FEV1 compared with placebo.

Omalizumab Improves Lung Function in Persistent Allergic Asthma

Omalizumab Improves Lung Function in Persistent Allergic Asthma

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Patients with moderate to severe persistent allergic asthma who were treated with omalizumab experienced greater improvements in lung function after 16 weeks compared with those treated with placebo.

Montelukast Plus Levocetirizine vs Monotherapy in Asthma, Allergic Rhinitis

Montelukast Plus Levocetirizine vs Monotherapy in Asthma, Allergic Rhinitis

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Montelukast plus levocetirizine demonstrated a significant reduction in mean daytime nasal symptom scores compared with montelukast monotherapy.

Severe Eosinophilic Asthma Effectively Managed With Benralizumab

Severe Eosinophilic Asthma Effectively Managed With Benralizumab

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Benralizumab was associated with a significant reduction in annual asthma exacerbation rates.

Complementary Alternative Medicine in Asthma Use Varies Among Racial/Ethnic Groups

Complementary Alternative Medicine in Asthma Use Varies Among Racial/Ethnic Groups

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Black and Hispanic respondents with asthma were less likely to use complementary alternative medicine than their white counterparts.

Inhaled Corticosteroid Therapy Refill Disruption Leads to Exacerbations

Inhaled Corticosteroid Therapy Refill Disruption Leads to Exacerbations

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Disrupting regular combination inhaled corticosteroid therapy refills increased hospitalizations and exacerbations.

Asthma Severity Does Not Affect Overall Asthma Control in Children

Asthma Severity Does Not Affect Overall Asthma Control in Children

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Regardless of severity, when children's asthma was appropriately managed according to guidelines, they experienced significant improvements.

Higher Childhood Asthma Risk From Recurring Acute Respiratory Infections

Higher Childhood Asthma Risk From Recurring Acute Respiratory Infections

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A higher number of acute respiratory infections before the age of 2 may increase the risk for asthma by age 7.

Reduced Perinatal Proteobacteria Exposure Linked to Childhood Wheezing

Reduced Perinatal Proteobacteria Exposure Linked to Childhood Wheezing

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Lower exposure to Proteobacteria in umbilical cord serum was associated with an increased risk for childhood wheezing.

Asthma Improved in African American Adolescents Using Comprehensive Treatment Plan

Asthma Improved in African American Adolescents Using Comprehensive Treatment Plan

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African-American adolescents with asthma had improved outcomes when they received a comprehensive treatment plan.

Metered Dose Inhaler Errors Affect Many With COPD and Asthma

Metered Dose Inhaler Errors Affect Many With COPD and Asthma

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The most common error related to the use of metered dose inhalers was the failure to attach the inhaler to a spacer.

Xolair Prefilled Syringe Formulation Gets FDA Approval

Xolair Prefilled Syringe Formulation Gets FDA Approval

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The PFS formulation eliminates the need to reconstitute the solution before administration.

Paraben Exposure and Childhood Asthma-Related Outcomes

Paraben Exposure and Childhood Asthma-Related Outcomes

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For every 10-fold rise in methyl and propyl concentrations, there was a 2.61 and a 2.18 increased prevalence odds ratio, respectively, of reporting an emergency department visit in the last 12 months in boys with asthma.

Addressing Smoking Cessation in Asthma

Addressing Smoking Cessation in Asthma

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Smoking cessation in patients with asthma is associated with reduced symptoms, improved lung function and quality of life, reduced use of rescue medications, improved airway hyperresponsiveness, and decreased hyperactivity.

Eosinophilic Asthma Treatment: Biologic Agents Compared

Eosinophilic Asthma Treatment: Biologic Agents Compared

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PubMed was searched to obtain data on the relative efficacies of benralizumab, dupilumab, lebrikizumab, mepolizumab, reslizumab, and tralokinumab.

Pest Allergies in Urban Adolescents Exacerbate Poorly Controlled Asthma

Pest Allergies in Urban Adolescents Exacerbate Poorly Controlled Asthma

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Cockroach and mouse allergies were most often associated with poorly controlled asthma and exacerbations in urban adolescents.

Allergy, But Not Asthma, Risk Increased in Children of East Asian Descent

Allergy, But Not Asthma, Risk Increased in Children of East Asian Descent

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Children of East Asian-born parents had an increased risk for allergic rhinitis and aeroallergen sensitization compared with children of Caucasian ancestry.

PUFAs Inversely Associated With Asthma in Preschool Children

PUFAs Inversely Associated With Asthma in Preschool Children

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Total omega-3 and omega-6 plasma polyunsaturated fatty acids relative abundances were significantly inversely correlated with asthma/recurrent wheeze and allergic sensitization.

Relationship Between Atopic Disorders May Be Age Dependent

Relationship Between Atopic Disorders May Be Age Dependent

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Although allergic sensitization and hay fever rates increased as children grew older, the rates of asthma dropped.

Benralizumab Efficacy Maintained in Long-Term Severe Eosinophilic Asthma Study

Benralizumab Efficacy Maintained in Long-Term Severe Eosinophilic Asthma Study

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Results from the extension trial showed a similar safety and tolerability profile for Fasenra as that seen in SIROCCO and CALIMA.

Ambient Particulate Matter Linked to Emergency Asthma Care

Ambient Particulate Matter Linked to Emergency Asthma Care

An increase was seen in asthma hospital visits with increasing ambient particulate matter in San Luis Valley.

Budesonide/Formoterol for the Prevention of Serious Asthma Exacerbations

Budesonide/Formoterol for the Prevention of Serious Asthma Exacerbations

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The SYGMA trials assessed the use of an as-needed combined corticosteroid/beta-agonist inhaler in patients with mild asthma.

Anti-IL5 Treatments Compared in Patients With Severe Eosinophilic Asthma

Anti-IL5 Treatments Compared in Patients With Severe Eosinophilic Asthma

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Currently, 3 anti-interleukin (IL)5 pathway-directed treatments (benralizumab, mepolizumab, reslizumab) have been approved by the Food and Drug Administration for the treatment of severe asthma with an eosinophilic phenotype.

Asthma Control Not Improved With School-Supervised Inhaled Corticosteroid Use

Asthma Control Not Improved With School-Supervised Inhaled Corticosteroid Use

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In a population of primarily Latino children from low-income households, a program of school-supervised use of once-daily inhaled corticosteroids failed to improve asthma control.

Childhood Asthma Risk Assessed Using Respiratory Phenotypes

Childhood Asthma Risk Assessed Using Respiratory Phenotypes

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Overall, 5 phenotypes were identified and differentiated mainly by patterns of wheezing and aeroallergen sensitization: low wheeze-low atopy, low wheeze-high atopy, transient wheeze-low atopy, high wheeze-low atopy, and high wheeze-high atopy.

IL-24 Shows Correlation Between Lower, Upper Airways in Allergic Asthma

IL-24 Shows Correlation Between Lower, Upper Airways in Allergic Asthma

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Nasal expression of interleukin-10 showed an association with perceived stress burden, while perceived stress burden was strongly associated with asthma control score.

Tezepelumab Gets Breakthrough Therapy Designation for Severe Asthma

Tezepelumab Gets Breakthrough Therapy Designation for Severe Asthma

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The designation was based on data from the Phase 2b PATHWAY trial that evaluated 3 doses of tezepelumab as add-on therapy in patients with a history of asthma exacerbations and uncontrolled asthma receiving inhaled corticosteroids/long-acting β-agonist with or without oral corticosteroids and additional asthma controllers vs placebo.

Asthma Affected Differently by Subcutaneous and Visceral Abdominal Fat

Asthma Affected Differently by Subcutaneous and Visceral Abdominal Fat

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Significant negative correlations were seen between visceral fat area and bronchial lumen diameter and lumen area, and significant positive correlations were seen between subcutaneous fat area and bronchial wall area and total area.

Prevalence of Asthma Exacerbations That Also Meet Anaphylaxis Criteria

Prevalence of Asthma Exacerbations That Also Meet Anaphylaxis Criteria

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A total of 8% of patients with asthma exacerbations met the criteria for diagnosing anaphylaxis, with 3.4% having likely experienced anaphylaxis.

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