Asthma

Early Child Care Attendance and Asthma, Wheeze Risk: What's the Link?

Early Child Care Attendance and Asthma, Wheeze Risk: What's the Link?

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Early child care attendance increased the risk for wheeze in children ≤2 years of age but decreased the risk for asthma in children 3 to 5 years of age.

Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

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Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

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A childhood measles infection may increase the risk for post-bronchodilator airflow obstruction in middle-age adults via its interaction with asthma and smoking.

Early Asthma Symptoms Linked to Lung Function in Adolescents Born Preterm

Early Asthma Symptoms Linked to Lung Function in Adolescents Born Preterm

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Preterm-born children had significantly more frequent preschool wheeze compared with children born at term.

No significant benefit of long-acting muscarinic antagonists over long-acting beta-agonists in reducing exacerbation risk in uncontrolled, persistent asthma

Adjunct long-acting muscarinic antagonist (LAMA) use with corticosteroids was associated with reduced exacerbation risk compared with placebo in patients with uncontrolled, persistent asthma. However, LAMA, long-acting beta-agonist (LABA), and inhaled corticosteroids (triple therapy) were not associated with lower risk for exacerbations compared with LABA and inhaled corticosteroids alone.

Asthma Exacerbation Risk Lower With SMART Therapy

Asthma Exacerbation Risk Lower With SMART Therapy

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In patients with persistent asthma, single maintenance and reliever therapy was associated with a lower risk for exacerbations compared with inhaled corticosteroids as controller therapy and short-acting beta-agonists as relief therapy.

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

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Regardless of blood eosinophil count, omalizumab was an effective treatment in adult and pediatric patients with severe allergic asthma.

Distinct Lung Function Trajectories Associated With COPD Risk

Distinct Lung Function Trajectories Associated With COPD Risk

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Researchers identified 6 distinct FEV1 lung function trajectories, 3 of which were responsible for 75% of the COPD burden.

Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

Findings for subsequent allergic disease following infant exposure in the first six months of life.

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

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Patients with asthma or chronic obstructive pulmonary disease have especially high rates of nonadherence, even in comparison with other chronic diseases.

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

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In children with allergic asthma, SCIT may reduce long-term asthma medication use.

Smartinhaler Sensor for Symbicort Will Be Available Over-the-Counter

Smartinhaler Sensor for Symbicort Will Be Available Over-the-Counter

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The Smartinhaler sensor is a device installed onto a patient's inhaler to monitor and promote asthma and COPD medication adherence.

Asthma Exacerbation Risk Reduced With Inhaled Corticosteroids Plus LABAs or LAMAs

Asthma Exacerbation Risk Reduced With Inhaled Corticosteroids Plus LABAs or LAMAs

Long-acting muscarinic antagonists or long-acting β-agonists plus inhaled corticosteroids lowered the risk for asthma exacerbations vs adjuvant placebo.

Asthma Development in Early Childhood May Hinge on Early Life Stress

Asthma Development in Early Childhood May Hinge on Early Life Stress

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Prenatal and early life stress, including societal stress, have been implicated in the development of asthma and other allergic diseases in children.

Increased inhaled glucocorticoids do not prevent asthma exacerbations in children: The STICS trial

In children aged 5 to 11 years with mild to moderate persistent asthma who were treated with daily inhaled glucocorticoids, quintupling the dose during the initial signs of worsening asthma control did not reduce the rate of severe exacerbations.

Effect of Tobacco Smoke Exposure in Children With or Without Asthma

Effect of Tobacco Smoke Exposure in Children With or Without Asthma

Current tobacco smoke exposure is not associated with airflow obstruction in school-aged children, but prenatal smoking is associated with airflow obstruction in children with asthma.

Severe Asthmatic Cough May Be Improved With Bronchial Thermoplasty

Severe Asthmatic Cough May Be Improved With Bronchial Thermoplasty

Bronchial thermoplasty can treat severe asthmatic cough that is unresponsive to conventional therapies.

Asthma Symptoms, Risks, and Comorbidities According to Smoking Status

Asthma Symptoms, Risks, and Comorbidities According to Smoking Status

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Smokers and nonsmokers had similar symptoms and risk factors present for asthma, but differed in comorbidities.

Asthma Medications May Negatively Affect Fertility in Women

Asthma Medications May Negatively Affect Fertility in Women

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Short-acting beta-agonists for asthma management may reduce fertility rates in women with asthma.

Effect of Allergen Exposure Reduction Efforts on Asthma Outcomes

Effect of Allergen Exposure Reduction Efforts on Asthma Outcomes

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According to a systematic literature review, there was inconclusive evidence that single indoor allergen interventions were effective at improving asthma outcomes.

Meeting Patients' Expectations for Asthma, Allergy Testing Improves Satisfaction

Meeting Patients' Expectations for Asthma, Allergy Testing Improves Satisfaction

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When patients visiting an allergy/immunology outpatient clinic had expectations met regarding diagnosis and testing, they were more likely to be satisfied with their visit.

Asthma in Primary Care: Spirometry Underused in Diagnosis

Asthma in Primary Care: Spirometry Underused in Diagnosis

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Spirometry may be underused for the diagnosis and monitoring of asthma in the primary care setting.

Biomarkers May Identify Patients at Increased Risk for Severe Asthma Exacerbations

Biomarkers May Identify Patients at Increased Risk for Severe Asthma Exacerbations

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Fractional exhaled nitric oxide, periostin, and eosinophils may help identify patients at increased risk for severe asthma exacerbations, according to a post hoc analysis of a phase 2b trial on dupilumab.

Early-Onset Eczema May Increase Risk for Childhood Asthma

Early-Onset Eczema May Increase Risk for Childhood Asthma

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Children diagnosed with eczema before the age of 2 years may be at increased risk for early-onset asthma.

Episodic Inhaled Treatment Effective in Children With Recurrent Wheezing, Persistent Asthma

Episodic Inhaled Treatment Effective in Children With Recurrent Wheezing, Persistent Asthma

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Episodically treating children with recurrent wheezing with inhaled combined salmeterol/fluticasone propionate may be as effective as a daily inhaled fluticasone propionate regimen.

Inhaler Use in Asthma and COPD: Patient Characteristics Compared

Inhaler Use in Asthma and COPD: Patient Characteristics Compared

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Researchers examined real-world characteristics of patients receiving albuterol multidose dry powder inhaler or short-acting β2 agonists with short-acting β2 agonists for asthma and chronic obstructive pulmonary disease.

Clinical Benefits of Adding Tiotropium to Asthma Maintenance Therapy

Clinical Benefits of Adding Tiotropium to Asthma Maintenance Therapy

Tiotropium, when added to standard asthma maintenance therapy, improves lung function in adult patients with symptomatic asthma regardless of GINA asthma severity.

Asthma, Allergic Rhinitis Prevalence With Long-Term Opioid Use

Asthma, Allergic Rhinitis Prevalence With Long-Term Opioid Use

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Patients with opioid dependence or abuse may exhibit a higher prevalence of asthma compared with the general population.

Chronic Oral Glucocorticoid Use in Pediatric Asthma May Increase Morbidities

Chronic Oral Glucocorticoid Use in Pediatric Asthma May Increase Morbidities

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Children with asthma who experience chronic oral glucocorticoid exposure may have significant morbidities, including adrenal suppression, recurrent pneumonia, and behavioral problems.

Mepolizumab Effective in Asthma After Failed Response to Omalizumab

Mepolizumab Effective in Asthma After Failed Response to Omalizumab

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Mepolizumab may be effective in patients with asthma that does not respond to omalizumab.

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