Chronic Obstructive Pulmonary Disease (COPD)

Dexamethasone Ineffective for Prevention of Acute Mountain Sickness in COPD

Dexamethasone Ineffective for Prevention of Acute Mountain Sickness in COPD

Dexamethasone was not effective in reducing the incidence of acute mountain sickness and altitude-related adverse health effects in individuals with mild to moderate COPD.

Umeclidinium/Vilanterol Efficacy Assessed in Elderly COPD Patients

Umeclidinium/Vilanterol Efficacy Assessed in Elderly COPD Patients

By

Study authors performed a post hoc pooled analysis of data from 10 trials to assess the safety and efficacy of umeclidinium/vilanterol in elderly symptomatic patients with COPD.

GERD and Nasal Symptoms Affect Bronchitis Symptom Severity in COPD

GERD and Nasal Symptoms Affect Bronchitis Symptom Severity in COPD

By

Gastroesophageal reflux disease is associated with an increase in bronchitis symptoms in patients with COPD.

Prolonged Leisure-Time Sitting Tied to Increased COPD Mortality Risk

Prolonged Leisure-Time Sitting Tied to Increased COPD Mortality Risk

Increase in all-cause, cardiovascular disease, cancer, diabetes, kidney disease, suicide, and COPD mortality.

FDA Approves Zephyr Endobronchial Valve for Treating Severe Emphysema

FDA Approves Zephyr Endobronchial Valve for Treating Severe Emphysema

By

The approval was based on results from a multicenter study (LIBERATE) of 190 patients with severe emphysema.

Use of Palliative Care, Oxygen Therapy Increasing for COPD

Use of Palliative Care, Oxygen Therapy Increasing for COPD

For patients with advanced COPD, the use of formal palliative care services and long-term oxygen therapy has increased but remains low.

Clinical Effect of Emphysema in Individuals With HIV

Clinical Effect of Emphysema in Individuals With HIV

By

The clinical significance of emphysema was greater in people living with HIV vs those without HIV.

COPD End-of-Life Management Strategies: Use Could Be Expanded

COPD End-of-Life Management Strategies: Use Could Be Expanded

By

The use of formal palliative care services among patients with chronic obstructive pulmonary disease increased by 1% per year, going from 5.3% in 2004 to 14.3% in 2014.

COPD Education Program Improved Patient Knowledge of Disease

COPD Education Program Improved Patient Knowledge of Disease

By

There was as significant change in Bristol COPD Knowledge Questionnaire scores in patients who received a brief education program at the time of an acute exacerbation of COPD.

Stroke, MI Risk Increased After Severe COPD Exacerbations

Stroke, MI Risk Increased After Severe COPD Exacerbations

By

Acute COPD exacerbations were associated with an increased risk for myocardial infarction and ischemic stroke.

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

By

Zephyr® Endobronchial Valve EBV® treatment improved FEV1 in patients with heterogeneous emphysema.

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

By

The inclusion of residual volume-to-total lung capacity ratio may add another dimension to COPD not routinely captured by standard airflow indices that could be predictive of lower maximum exercise capacity.

COPD Triple Therapy Switch to LABA/LAMA May Be Appropriate in Some Patients

COPD Triple Therapy Switch to LABA/LAMA May Be Appropriate in Some Patients

A direct de-escalation from triple therapy to indacaterol/glycopyrronium may be appropriate in patients with infrequent COPD exacerbations.

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

By

A definition of a pulmonary vascular phenotype of chronic obstructive pulmonary disease has been proposed.

E-Cigarette Use Associated With Increased Risk for COPD

E-Cigarette Use Associated With Increased Risk for COPD

By

Using e-cigarettes every day or some days increased the likelihood of developing chronic obstructive pulmonary disease.

COPD Frequently Misdiagnosed, Undiagnosed in Individuals With or Without HIV

COPD Frequently Misdiagnosed, Undiagnosed in Individuals With or Without HIV

By

In this study, researchers examined the appropriateness of diagnosis and treatment of chronic obstructive pulmonary disease in individuals with and without HIV.

Mortality Rates in Extrafine ICS-Containing vs ICS-Free Medications in COPD

Mortality Rates in Extrafine ICS-Containing vs ICS-Free Medications in COPD

By

The pooled safety analysis included data from the TRILOGY, TRINITY, and TRIBUTE studies.

Incident Diuretic Use May Increase Adverse Events in COPD

Incident Diuretic Use May Increase Adverse Events in COPD

Incident diuretic use was associated with increased rates of respiratory-related morbidity and mortality in older adults with chronic obstructive pulmonary disease.

Assessing Depression Following Inpatient COPD Rehabilitation

Assessing Depression Following Inpatient COPD Rehabilitation

By

PHQ-9 and PHQ-2 show factorial validity, invariance, and reliability for measuring depression in patients with chronic obstructive pulmonary disease.

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

By

Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative care consultation was linked to a reduction in hospital costs for hospitalized adults with serious illness, such as COPD.

Survival Predictors When Life Support Is Withheld in ICU

Survival Predictors When Life Support Is Withheld in ICU

By

Survival at 6 months was significantly associated with acute respiratory failure and history of COPD.

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

By

A higher proportion of patients with COPD and a blood eosinophil count of ≥0.34×109/L had elevated markers of low-grade systemic inflammation regardless of forced expiratory volume in 1 second.

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

By

Readmission rates were highest during the first 72 hours after admission for an acute exacerbation of chronic obstructive pulmonary disease.

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

By

Adding olodaterol to tiotropium did not significantly reduce exacerbations in patients with chronic obstructive pulmonary disease as much as researchers had anticipated.

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

By

Asthma and COPD overlap linked to higher prevalence of sleep-related symptoms, including difficulty falling asleep and maintaining sleep, early-morning awakening, and excessive daytime sleepiness.

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

By

The drug consists of fluticasone furoate, an inhaled corticosteroid (ICS), umeclidinium, a long-acting muscarinic antagonist, and vilanterol, a long-acting beta2-adrenergic agonist (LABA), delivered via an Ellipta dry powder inhaler.

Transcatheter vs Surgical Aortic Valve Replacement in COPD

Transcatheter vs Surgical Aortic Valve Replacement in COPD

By

In patients with COPD, transcatheter aortic valve replacement was associated with fewer respiratory-related complications than surgical aortic valve replacement.

Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

By

Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple therapy with fluticasone furoate, umeclidinium, and vilanterol was associated with a lower rate of exacerbations in chronic obstructive pulmonary disease.

Sign Up for Free e-newsletters