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New Biomarker May Enable Selective Antibiotic Use for COPD Exacerbation

New Biomarker May Enable Selective Antibiotic Use for COPD Exacerbation

Researchers hypothosized that increased sputum Gammaproteobacteria:Firmicutes ratio may serve as a biomarker to guide antibiotic treatment in COPD.

Reduced Mortality Risk in COPD Linked to Statin Tx

Reduced Mortality Risk in COPD Linked to Statin Tx

People with COPD have been found to benefit from statin therapies, with reduced risk of all-cause and pulmonary-related mortality.

COPD Exacerbations May Be Reduced With Mucolytic Agents

COPD Exacerbations May Be Reduced With Mucolytic Agents

Patients with COPD treated with mucolytic agents for at least 1 year were better protected against exacerbations compared with patients treated with placebo.

COPD Diagnosis by Physician vs Spirometry: A Validation Study

COPD Diagnosis by Physician vs Spirometry: A Validation Study

Questions involving physician-diagnosed COPD have a low sensitivity and a high specificity.

Efficacy of Tiotropium in Mild to Moderate COPD Examined

Efficacy of Tiotropium in Mild to Moderate COPD Examined

FEV1 was higher in patients who received tiotropium therapy vs those in the placebo group.

COPD Linked to Diabetes and Post-Diabetes Pneumonia

COPD Linked to Diabetes and Post-Diabetes Pneumonia

Patients with chronic obstructive pulmonary disease, particularly with exacerbations, have an increased risk for diabetes development.

Asthma and COPD: Updates on Prevalence, Disability, and Mortality

Asthma and COPD: Updates on Prevalence, Disability, and Mortality

A 2015 update from the 1990 Global Burden of Disease study reveals current prevalence and mortality of asthma and chronic obstructive pulmonary disease.

Improving Lung Function, QoL in COP With Once-Daily Triple-Tx

Improving Lung Function, QoL in COP With Once-Daily Triple-Tx

Study results showed the benefit of single-inhaler triple therapy vs ICS/LABA therapy in COPD.

Does Procalcitonin Testing in COPD Impact Antibiotic Rx?

Does Procalcitonin Testing in COPD Impact Antibiotic Rx?

Researchers found a weak negative association between PCT testing rate and risk-adjusted antibiotic initiation rate.

Pulmonary Rehabilitation Benefits in COPD, Lung Cancer, and Other Respiratory Conditions

Pulmonary Rehabilitation Benefits in COPD, Lung Cancer, and Other Respiratory Conditions

Recent research suggests that perioperative and postoperative pulmonary rehabilitation improves outcomes in patients undergoing thoracic surgery.

Fracture Risk in COPD Increases With Extended Duration of Corticosteroid Use

Fracture Risk in COPD Increases With Extended Duration of Corticosteroid Use

Inhaled corticosteroids for COPD does not increase the risk for fractures when used for short-term periods.

Respiratory Therapist Autonomy With Noninvasive Ventilation May Improve COPD Outcomes

Respiratory Therapist Autonomy With Noninvasive Ventilation May Improve COPD Outcomes

Timely selection and early intervention, attention to comfort, and frequent checks improved outcomes in patients with chronic obstructive pulmonary disease who were treated with noninvasive ventilation.

Errors in Spirometry, Primary Care Contribute to COPD Misdiagnosis

Errors in Spirometry, Primary Care Contribute to COPD Misdiagnosis

Chronic obstructive pulmonary disease may be misdiagnosed in patients as a result of errors related to spirometry tests, errors made in primary care, and differential diagnoses, among others.

Loss of Lung Function Slowed With Fluticasone Furoate Tx

Loss of Lung Function Slowed With Fluticasone Furoate Tx

The rate of forced expiratory volume in one second decline in patients with moderate COPD can be reduced by regular use of fluticasone furoate, either alone or in combination with vilanterol.

Avoiding Pneumonia in Patients With COPD

Avoiding Pneumonia in Patients With COPD

Pneumonia primarily affects young children, smokers, adults 65 years and older, and people with COPD.

Boosting Rehabilitation in Adults With COPD Through Social Support

Boosting Rehabilitation in Adults With COPD Through Social Support

Researchers examined structural social support indicators, including living status, having a partner, number of close friends and relatives, and the presence of a family caregiver.

LABA/LAMA Combination Therapy Associated With Lower CV, Cerebrovascular Risks in COPD

LABA/LAMA Combination Therapy Associated With Lower CV, Cerebrovascular Risks in COPD

Cardio- and cerebrovascular events were more common in patients being treated with combination long-acting β2-agonist (LABA)/long-acting muscarinic antagonist (LAMA) therapies vs LABA/inhaled corticosteroids.

Diagnostic Measures of Lung Function Decline in COPD

Diagnostic Measures of Lung Function Decline in COPD

Comparative measures of inspiratory vs expiratory volumes show a penumbra of lung tissue at higher risk of damage from existing COPD.

Managing COPD Exacerbations With Doxycycline Plus Prednisone

Managing COPD Exacerbations With Doxycycline Plus Prednisone

The first study of antibiotic use in outpatients with COPD exacerbations found that doxycycline plus prednisone did not prolong the time between exacerbations.

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