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Unraveling the Relationship Between COPD and Stroke

Unraveling the Relationship Between COPD and Stroke

Although COPD has been identified as a risk factor for cardiovascular disease, researchers are less certain about the relationship between COPD and stroke.

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Whole-Genome Sequencing Proves Valuable in Severe COPD

Whole-Genome Sequencing Proves Valuable in Severe COPD

Whole-genome sequencing was valuable in identifying a large number of potentially significant functional variants in severe COPD.

Unraveling the Relationship Between COPD and Stroke

Unraveling the Relationship Between COPD and Stroke

Although COPD has been identified as a risk factor for cardiovascular disease, researchers are less certain about the relationship between COPD and stroke.

Childhood Respiratory Risk Factor Profiles Predict Lung Function, COPD

Childhood Respiratory Risk Factor Profiles Predict Lung Function, COPD

Frequent asthma, bronchitis, allergy demonstrated the strongest association with , lower FEV1, lower FEV1/forced vital capacity, and increased risk for COPD.

Dexamethasone Ineffective for Prevention of Acute Mountain Sickness in COPD

Dexamethasone Ineffective for Prevention of Acute Mountain Sickness in COPD

Dexamethasone was not effective in reducing the incidence of acute mountain sickness and altitude-related adverse health effects in individuals with mild to moderate COPD.

Tiotropim/Olodaterol Safe, Tolerable in COPD Regardless of Renal Impairment

Tiotropim/Olodaterol Safe, Tolerable in COPD Regardless of Renal Impairment

Regardless of renal impairment, combination therapy with tiotropium/olodaterol was safe and tolerable in patients with moderate to very severe COPD.

Umeclidinium/Vilanterol Efficacy Assessed in Elderly COPD Patients

Umeclidinium/Vilanterol Efficacy Assessed in Elderly COPD Patients

Study authors performed a post hoc pooled analysis of data from 10 trials to assess the safety and efficacy of umeclidinium/vilanterol in elderly symptomatic patients with COPD.

GERD and Nasal Symptoms Affect Bronchitis Symptom Severity in COPD

GERD and Nasal Symptoms Affect Bronchitis Symptom Severity in COPD

Gastroesophageal reflux disease is associated with an increase in bronchitis symptoms in patients with COPD.

Prolonged Leisure-Time Sitting Tied to Increased COPD Mortality Risk

Prolonged Leisure-Time Sitting Tied to Increased COPD Mortality Risk

Increase in all-cause, cardiovascular disease, cancer, diabetes, kidney disease, suicide, and COPD mortality.

FDA Approves Zephyr Endobronchial Valve for Treating Severe Emphysema

FDA Approves Zephyr Endobronchial Valve for Treating Severe Emphysema

The approval was based on results from a multicenter study (LIBERATE) of 190 patients with severe emphysema.

Use of Palliative Care, Oxygen Therapy Increasing for COPD

Use of Palliative Care, Oxygen Therapy Increasing for COPD

For patients with advanced COPD, the use of formal palliative care services and long-term oxygen therapy has increased but remains low.

Clinical Effect of Emphysema in Individuals With HIV

Clinical Effect of Emphysema in Individuals With HIV

The clinical significance of emphysema was greater in people living with HIV vs those without HIV.

COPD End-of-Life Management Strategies: Use Could Be Expanded

COPD End-of-Life Management Strategies: Use Could Be Expanded

The use of formal palliative care services among patients with chronic obstructive pulmonary disease increased by 1% per year, going from 5.3% in 2004 to 14.3% in 2014.

Patient With COPD, Smoking History Presents to ED With Sensory Loss

Patient With COPD, Smoking History Presents to ED With Sensory Loss

A 72-year-old man with a 50 pack-year smoking history and multiple comorbidities, including COPD, presents to the emergency department with left-sided hemiparesis and sensory loss.

COPD Education Program Improved Patient Knowledge of Disease

COPD Education Program Improved Patient Knowledge of Disease

There was as significant change in Bristol COPD Knowledge Questionnaire scores in patients who received a brief education program at the time of an acute exacerbation of COPD.

Stroke, MI Risk Increased After Severe COPD Exacerbations

Stroke, MI Risk Increased After Severe COPD Exacerbations

Acute COPD exacerbations were associated with an increased risk for myocardial infarction and ischemic stroke.

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Zephyr® Endobronchial Valve EBV® treatment improved FEV1 in patients with heterogeneous emphysema.

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

The inclusion of residual volume-to-total lung capacity ratio may add another dimension to COPD not routinely captured by standard airflow indices that could be predictive of lower maximum exercise capacity.

COPD Triple Therapy Switch to LABA/LAMA May Be Appropriate in Some Patients

COPD Triple Therapy Switch to LABA/LAMA May Be Appropriate in Some Patients

A direct de-escalation from triple therapy to indacaterol/glycopyrronium may be appropriate in patients with infrequent COPD exacerbations.

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

A definition of a pulmonary vascular phenotype of chronic obstructive pulmonary disease has been proposed.

COPD and the "Obesity Paradox:" Is a Higher BMI Protective?

COPD and the "Obesity Paradox:" Is a Higher BMI Protective?

Recent research suggests that increasing obesity class is independently associated with worse respiratory-specific and general quality of life outcomes in COPD.

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