Patients with obesity who are hospitalized for an acute exacerbation of COPD may have longer hospital stays and more often require mechanical ventilation.
Salmeterol plus fluticasone was associated with a significant increase in sputum bacterial load in chronic obstructive pulmonary disease, compared to salmeterol alone.
Rheumatoid arthritis increased the risk of COPD-related hospitalization by 47%.
Impulse oscillometry is a better monitor of airway obstruction compared with spirometry in patients with chronic obstructive pulmonary disease.
In a retrospective analysis, researchers examined the efficacy of beta blocker therapy in prolonging patients' lives.
A 3-variable score that encompasses dyspnea score, prednisone use, and prior hospitalization for COPD exacerbations can predict mortality and readmission risk.
A recent study examined whether nebulized glycopyrrolate is safe to use in patients with severe COPD and comorbid cardiovascular risk factors.
Both reduced forced vital capacity and a restrictive spirometry pattern was associated with arterial stiffness in both men and women.
Mortality rates and changes in mortality rates for chronic respiratory diseases in the United States varied by county, sex, and particular disease type.
In contrast to previous study findings, inhaled corticosteroids do not appear to increase risk for pneumonia in patients with COPD with moderate airflow limitation.
Coronary artery calcium may be the best noninvasive risk marker for predicting cardiovascular events in patients with chronic obstructive pulmonary disease.
The European Respiratory Society and American Thoracic Society have released updated guidelines on the use of noninvasive ventilation for acute respiratory failure.
Long-acting muscarinic antagonists plus long-acting beta-agonists for COPD is associated with fewer exacerbations compared with long-acting beta-agonists plus inhaled corticosteroids.
Patients with COPD who have elevated blood eosinophilic levels may benefit from treatment with mepolizumab.
Current and former smokers with COPD had much higher total airway mucin concentrations compared with patients who had never smoked.
A multidisciplinary palliative care team may significantly benefit patients with chronic obstructive pulmonary disease.
In patients with mild or moderate chronic obstructive pulmonary disease, tiotropium improved the decline in FEV1, as well as quality of life.
Patients with COPD and comorbid cardiovascular disease may benefit from statin treatment depending on their C - reactive protein levels.
After accounting for individual risk factors, living altitude is not associated with variability in COPD prevalence.
Two phase 3 clinical trials examined mepolizumab 100 or 300 mg vs placebo to treat moderate-to-severe COPD exacerbations.