Frequent asthma, bronchitis, allergy demonstrated the strongest association with , lower FEV1, lower FEV1/forced vital capacity, and increased risk for COPD.
Regardless of renal impairment, combination therapy with tiotropium/olodaterol was safe and tolerable in patients with moderate to very severe COPD.
A 72-year-old man with a 50 pack-year smoking history and multiple comorbidities, including COPD, presents to the emergency department with left-sided hemiparesis and sensory loss.
Tiotropium may be more effective in reducing the rate of moderate and severe chronic obstructive pulmonary disorder exacerbations when used in combination with olodaterol vs tiotropium alone.
Patients with COPD had a nearly 2-fold increased risk for developing atrial fibrillation compared with patients without COPD.
Steroid dosing and glucose levels were not associated with an increase in hospital readmissions related to COPD exacerbations.
No association was found between the degree of lung function impairment and the development of mild cognitive impairment in chronic obstructive pulmonary disease.
Combination therapy with LABA and LAMA yielded a lower annualized rate of COPD exacerbations compared with triple therapy.
Individuals with chronic obstructive pulmonary disease who met physical activity guidelines experienced the greatest reductions in all-cause, CVD, and respiratory mortality risk.
Independent predictive factors of lung cancer in chronic obstructive pulmonary disease may include frequency of exacerbations, in addition to airflow obstruction and visual emphysema.
Researchers used data from the Atherosclerosis Risk in Communities Study to assess associations between dietary pattern and pulmonary assessments.
One-year mortality after the initial hospitalization for chronic obstructive pulmonary disease exacerbation was related to clinical characteristics of the patient and of the index event.
An 80-year-old man with a history of smoking, hypertension, diabetes, and COPD presents to the emergency department with dyspnea at rest and chest tightness.
A significant reduction in severe COPD exacerbations was seen with intensified combination therapy at the onset of upper respiratory tract infections.
Patients with COPD may increase their physical activity levels using a home-based coaching intervention.
Women with rheumatoid arthritis had an increased risk for chronic obstructive pulmonary disease, but did not have an increased risk for asthma compared with women without RA.
Within the first 30 days of therapy, patients with COPD who began using long-acting bronchodilators had a 1.5-fold increased risk for cardiovascular events.
At a research seminar held by the European Respiratory Society in February 2017, a group of investigators discussed how precision medicine may improve treatment in asthma and COPD.
Sputum eosinophil counts may be a better predictor of COPD exacerbations compared with serum blood eosinophil counts.
Patients with asthma were found to have higher blood eosinophil counts, fractional exhaled nitric oxide levels, and total serum IgE concentrations compared with patients with COPD.
A 3-variable score that encompasses dyspnea score, prednisone use, and prior hospitalization for COPD exacerbations can predict mortality and readmission risk.
The safety of concurrently administering nebulized glycopyrrolate with long-acting beta agonists was examined in 3 studies.
Coronary artery calcium may be the best noninvasive risk marker for predicting cardiovascular events in patients with chronic obstructive pulmonary disease.
Long-acting muscarinic antagonists plus long-acting beta-agonists for COPD is associated with fewer exacerbations compared with long-acting beta-agonists plus inhaled corticosteroids.
A multidisciplinary palliative care team may significantly benefit patients with chronic obstructive pulmonary disease.
Questions involving physician-diagnosed COPD have a low sensitivity and a high specificity.
Patients with chronic obstructive pulmonary disease, particularly with exacerbations, have an increased risk for diabetes development.
Researchers found a weak negative association between PCT testing rate and risk-adjusted antibiotic initiation rate.
Timely selection and early intervention, attention to comfort, and frequent checks improved outcomes in patients with chronic obstructive pulmonary disease who were treated with noninvasive ventilation.
Chronic obstructive pulmonary disease may be misdiagnosed in patients as a result of errors related to spirometry tests, errors made in primary care, and differential diagnoses, among others.