COPD

Childhood Respiratory Risk Factor Profiles Predict Lung Function, COPD

Childhood Respiratory Risk Factor Profiles Predict Lung Function, COPD

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Frequent asthma, bronchitis, allergy demonstrated the strongest association with , lower FEV1, lower FEV1/forced vital capacity, and increased risk for COPD.

Tiotropim/Olodaterol Safe, Tolerable in COPD Regardless of Renal Impairment

Tiotropim/Olodaterol Safe, Tolerable in COPD Regardless of Renal Impairment

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Regardless of renal impairment, combination therapy with tiotropium/olodaterol was safe and tolerable in patients with moderate to very severe COPD.

Patient With COPD, Smoking History Presents to ED With Sensory Loss

Patient With COPD, Smoking History Presents to ED With Sensory Loss

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A 72-year-old man with a 50 pack-year smoking history and multiple comorbidities, including COPD, presents to the emergency department with left-sided hemiparesis and sensory loss.

Tiotropium/Olodaterol Combination vs Tiotropium Alone for Severe COPD Exacerbations

Tiotropium/Olodaterol Combination vs Tiotropium Alone for Severe COPD Exacerbations

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Tiotropium may be more effective in reducing the rate of moderate and severe chronic obstructive pulmonary disorder exacerbations when used in combination with olodaterol vs tiotropium alone.

COPD May Increase the Risk for Atrial Fibrillation

COPD May Increase the Risk for Atrial Fibrillation

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Patients with COPD had a nearly 2-fold increased risk for developing atrial fibrillation compared with patients without COPD.

Steroid Dosing, Glucose Levels Do Not Increase Likelihood of COPD Readmissions

Steroid Dosing, Glucose Levels Do Not Increase Likelihood of COPD Readmissions

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Steroid dosing and glucose levels were not associated with an increase in hospital readmissions related to COPD exacerbations.

Lung Function Impairment Level in COPD Not Related to Cognitive Impairment

Lung Function Impairment Level in COPD Not Related to Cognitive Impairment

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No association was found between the degree of lung function impairment and the development of mild cognitive impairment in chronic obstructive pulmonary disease.

Effect of Combination vs Triple Therapy on COPD Exacerbations

Effect of Combination vs Triple Therapy on COPD Exacerbations

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Combination therapy with LABA and LAMA yielded a lower annualized rate of COPD exacerbations compared with triple therapy.

COPD Mortality Risk and Physical Activity Have Dose-Response Relationship

COPD Mortality Risk and Physical Activity Have Dose-Response Relationship

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Individuals with chronic obstructive pulmonary disease who met physical activity guidelines experienced the greatest reductions in all-cause, CVD, and respiratory mortality risk.

Lung Cancer Risk May Be Predicted by Frequency of COPD Exacerbations

Lung Cancer Risk May Be Predicted by Frequency of COPD Exacerbations

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Independent predictive factors of lung cancer in chronic obstructive pulmonary disease may include frequency of exacerbations, in addition to airflow obstruction and visual emphysema.

COPD, Respiratory Symptoms Associated With "Western" Diet

COPD, Respiratory Symptoms Associated With "Western" Diet

Researchers used data from the Atherosclerosis Risk in Communities Study to assess associations between dietary pattern and pulmonary assessments.

Predictors of Mortality After Hospitalization for COPD Exacerbation

Predictors of Mortality After Hospitalization for COPD Exacerbation

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One-year mortality after the initial hospitalization for chronic obstructive pulmonary disease exacerbation was related to clinical characteristics of the patient and of the index event.

Clinical Challenge: Elderly Man Presents With Dyspnea at Rest and Chronic Cough

Clinical Challenge: Elderly Man Presents With Dyspnea at Rest and Chronic Cough

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An 80-year-old man with a history of smoking, hypertension, diabetes, and COPD presents to the emergency department with dyspnea at rest and chest tightness.

Preventing COPD Exacerbations in Upper Respiratory Tract Infections

Preventing COPD Exacerbations in Upper Respiratory Tract Infections

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A significant reduction in severe COPD exacerbations was seen with intensified combination therapy at the onset of upper respiratory tract infections.

COPD Home-Based Coaching Intervention: Effects on Physical Activity, Healthcare Utilization

COPD Home-Based Coaching Intervention: Effects on Physical Activity, Healthcare Utilization

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Patients with COPD may increase their physical activity levels using a home-based coaching intervention.

COPD and Asthma Risk in Women With Rheumatoid Arthritis

COPD and Asthma Risk in Women With Rheumatoid Arthritis

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Women with rheumatoid arthritis had an increased risk for chronic obstructive pulmonary disease, but did not have an increased risk for asthma compared with women without RA.

Inhaled Long-Acting Bronchodilators for COPD: Potential Cardiovascular Risk

Inhaled Long-Acting Bronchodilators for COPD: Potential Cardiovascular Risk

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Within the first 30 days of therapy, patients with COPD who began using long-acting bronchodilators had a 1.5-fold increased risk for cardiovascular events.

Precision Medicine May Pave the Way for Better Treatment in Asthma, COPD

Precision Medicine May Pave the Way for Better Treatment in Asthma, COPD

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At a research seminar held by the European Respiratory Society in February 2017, a group of investigators discussed how precision medicine may improve treatment in asthma and COPD.

Predicting COPD Exacerbations Using Sputum vs Blood Eosinophils

Predicting COPD Exacerbations Using Sputum vs Blood Eosinophils

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Sputum eosinophil counts may be a better predictor of COPD exacerbations compared with serum blood eosinophil counts.

Biomarkers Useful for Differentiating Between Asthma and COPD

Biomarkers Useful for Differentiating Between Asthma and COPD

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Patients with asthma were found to have higher blood eosinophil counts, fractional exhaled nitric oxide levels, and total serum IgE concentrations compared with patients with COPD.

COPD Hospital Readmission, Mortality Risk Predicted by 3-Variable Score

COPD Hospital Readmission, Mortality Risk Predicted by 3-Variable Score

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A 3-variable score that encompasses dyspnea score, prednisone use, and prior hospitalization for COPD exacerbations can predict mortality and readmission risk.

COPD: Concurrent Nebulized Glycopyrrolate, Long-Acting Bronchodilators Safe

COPD: Concurrent Nebulized Glycopyrrolate, Long-Acting Bronchodilators Safe

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The safety of concurrently administering nebulized glycopyrrolate with long-acting beta agonists was examined in 3 studies.

Using Coronary Artery Calcium to Predict Cardiovascular Events in COPD

Using Coronary Artery Calcium to Predict Cardiovascular Events in COPD

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Coronary artery calcium may be the best noninvasive risk marker for predicting cardiovascular events in patients with chronic obstructive pulmonary disease.

LABA Plus LAMA Therapy Associated With Fewer Exacerbations in COPD

LABA Plus LAMA Therapy Associated With Fewer Exacerbations in COPD

Long-acting muscarinic antagonists plus long-acting beta-agonists for COPD is associated with fewer exacerbations compared with long-acting beta-agonists plus inhaled corticosteroids.

Palliative Care Approaches for Patients with Chronic Obstructive Pulmonary Disease

Palliative Care Approaches for Patients with Chronic Obstructive Pulmonary Disease

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A multidisciplinary palliative care team may significantly benefit patients with chronic obstructive pulmonary disease.

COPD Diagnosis by Physician vs Spirometry: A Validation Study

COPD Diagnosis by Physician vs Spirometry: A Validation Study

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Questions involving physician-diagnosed COPD have a low sensitivity and a high specificity.

COPD Linked to Diabetes and Post-Diabetes Pneumonia

COPD Linked to Diabetes and Post-Diabetes Pneumonia

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Patients with chronic obstructive pulmonary disease, particularly with exacerbations, have an increased risk for diabetes development.

Does Procalcitonin Testing in COPD Impact Antibiotic Rx?

Does Procalcitonin Testing in COPD Impact Antibiotic Rx?

Researchers found a weak negative association between PCT testing rate and risk-adjusted antibiotic initiation rate.

Respiratory Therapist Autonomy With Noninvasive Ventilation May Improve COPD Outcomes

Respiratory Therapist Autonomy With Noninvasive Ventilation May Improve COPD Outcomes

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Timely selection and early intervention, attention to comfort, and frequent checks improved outcomes in patients with chronic obstructive pulmonary disease who were treated with noninvasive ventilation.

Errors in Spirometry, Primary Care Contribute to COPD Misdiagnosis

Errors in Spirometry, Primary Care Contribute to COPD Misdiagnosis

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Chronic obstructive pulmonary disease may be misdiagnosed in patients as a result of errors related to spirometry tests, errors made in primary care, and differential diagnoses, among others.

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