There was a significant relationship between brain natriuretic peptide levels and mortality in patients with group 1 pulmonary arterial hypertension.
Increased circulating immature granulocytes at the acute phase of sepsis are linked to clinical worsening, especially when associated with T-cell lymphopenia.
The Pulmonary Arterial Hypertension-Symptoms and Impact questionnaire has good psychometric properties and can be administered in clinical practice.
The "egg-and-banana" sign is a valid computed tomography marker of pulmonary hypertension.
Lung ultrasound was more effective in diagnosing pediatric community-acquired pneumonia than chest radiography.
Infant pulmonary function testing detected 3 distinct phenotypes in severe bronchopulmonary dysplasia.
D-dimer test adjustment based on pretest probability results may be a safe option to reduce the need for imaging during evaluation for pulmonary embolism.
Portable sleep monitoring may accurately diagnose sleep apnea in patients who are hospitalized with heart failure.
PHQ-9 and PHQ-2 show factorial validity, invariance, and reliability for measuring depression in patients with chronic obstructive pulmonary disease.
Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.
Low-dose computed tomography may assist clinicians in modifying diagnosis of elderly patients who are admitted with suspected pneumonia.
Experts in interstitial lung disease identified 18 items of importance for diagnosing chronic hypersensitivity pneumonitis.
Ischemic heart disease and kidney dysfunction were identified as 2 comorbidities that may affect outcomes in idiopathic pulmonary arterial hypertension.
Researchers developed an algorithmic approach to diagnosing lung cavitary diseases.
Greater Pi10 was associated with incident spirometry-defined chronic obstructive pulmonary disease in a general population-based sample without clinical lung disease.
N-terminal-pro brain natriuretic peptide may be a useful biomarker for both mortality and respiratory exacerbations in pediatric patients with pulmonary hypertension.
Peak flow meter, microspirometry are optimal, with full spirometry for positive results.
Differences in serum inflammatory markers may exist between patients with community-acquired pneumonia who present within the first 48 hours of symptom onset vs those who present later.
Further research on rapid tests is warranted, as industry-sponsored research tends to favor the industry's product and affects how physicians practice medicine.
The hemodynamic parameters predict mortality and cardiac hospitalization in patients with heart failure with preserved ejection fraction.
Adults with community-acquired pneumonia that is visualized on CT scan but not on concurrent chest radiograph have similar pathogens, disease severity, and outcomes as patients who had pneumonia confirmed via chest radiograph.
Interventional reduction of the angiopoietin-1/angiopoietin-2 ratio may provide therapeutic perspective for prevention of acute lung injury in pneumonia.
A routine chest radiograph after ultrasound-guided central venous catheter insertion is now considered costly and unnecessary.
Patients with pulmonary arterial hypertension may be better identified through a claims-based algorithm that includes ICD-9-CM codes, specific pulmonary arterial hypertension medications, echocardiography, and right heart catheterization.
The Clinical COPD Questionnaire cutoff point of 1.4 demonstrated a better agreement with other COPD measures in patients with more symptomatic disease.
Patients with chronic obstructive pulmonary disease with 5% emphysema based on thoracic computed tomography (CT) imaging may be at a greater risk for poor outcomes.
An integrated proteomic classifier accurately identified benign lung nodules when used in patients with a pretest probability of malignancy ≤50%.
Spirometry may be underused for the diagnosis and monitoring of asthma in the primary care setting.
Fractional exhaled nitric oxide, periostin, and eosinophils may help identify patients at increased risk for severe asthma exacerbations, according to a post hoc analysis of a phase 2b trial on dupilumab.
Children who had both parental and sibling asthma in their families had an increased risk for asthma.
Peak circulatory power offers greater value than peak oxygen uptake and ventilation in predicting cardiac events in patients with idiopathic PAH.
Pulmonary Embolism Rule-out Criteria non-inferior to usual care for patients at low-risk for pulmonary embolism
In this multicenter, randomized controlled study, the Pulmonary Embolism Rule-out Criteria (PERC) strategy resulted in significantly fewer uses of CT pulmonary angiography, reduced ED length of stay, and fewer hospital admissions.
High levels of C-reactive protein and neutrophils as well as low eosinophil count predicted a poor prognosis in COPD.
A CHEST expert panel has released updated guidelines for lung cancer screening.
Patients with suspected PH should undergo two 6MWTs to improve the accuracy of exercise capacity measurements.
Researchers examined variation in airway branches to determine whether they have an effect on the course of chronic obstructive pulmonary disease.
The 6-minute walk test had prognostic value with respect to mortality in a population of patients with pulmonary arterial hypertension.
Brain natriuretic peptide levels may accurately predict 5-year survival rates in patients with pulmonary arterial hypertension.
Although the 2017 GOLD classification did not better predict mortality in patients with chronic obstructive pulmonary disease overall, it did so when patients were extensively categorized by severity.
Patients who received provider-ordered influenza testing were more likely to be younger and present with fever and "influenza-like illness."
No data have demonstrated improved mortality, morbidity, or quality of life as a result of screening for COPD in asymptomatic individuals.
Lung cancer screening is more effective and efficient for high-risk individuals.
Although the Wells and revised Geneva scores are used in the general population to predict pulmonary embolism, researchers found they were not reliable in pregnant and postpartum women.
Pulmonary hemodynamic changes in chronic thromboembolic pulmonary hypertension may be monitored via the 6-minute walk test.
A gas-capillary column ion mobility spectrometer may be a feasible and noninvasive tool for clinicians to diagnose respiratory tract infections in hospitalized patients.
Researchers identified 4 specific symptoms that could be the basis for a pneumonia diagnosis.
Fractional exhaled nitric oxide measurement can diagnose asthma in patients 5 years and older.
Midturbinate swabs for influenza detection provided a more comfortable experience for patients compared with traditional nasopharyngeal swabs.
The use of spirometry during infancy or early adulthood may help identify individuals at risk for poor health outcomes
Sputum eosinophil counts may be a better predictor of COPD exacerbations compared with serum blood eosinophil counts.
No single finding appears to reliably predict a pneumonia diagnosis in pediatric patients younger than 5 years of age.
The 2006 CHEST management algorithms for acute, subacute, and chronic cough appear to be useful in treating adults globally.
Hemodynamics may improve in patients with chronic thromboembolic pulmonary hypertension after balloon pulmonary angioplasty with complication rates comparable to pulmonary endarterectomy.
PanCan study effectively identified patients who eventually developed early-stage lung cancer, compared to other predictive models.
Results indicate that further study of the relationship between the 6-minute walk distance test and functional capacity in PAH is necessary.
The relationship between negative tuberculin skin test and in-hospital mortality has not been previously studied.
A new diagnostic test and algorithm may be able to diagnose lung cancer from tumor-educated platelets.
Recommendations to include CT scans as standard follow-up procedure is based on poor evidence.
Charleston comorbidity index is an independent predictor of mortality in patients with hemodynamically stable pulmonary embolism.
Questions involving physician-diagnosed COPD have a low sensitivity and a high specificity.
Patients who underwent lung CT screening had a higher 2-week smoking cessation rate vs patients who did not undergo screening.
Researchers examined the efficacy of digital immunoassays vs rapid influenza diagnostic tests for diagnosing influenza.
A new algorithm developed by the National Institute for Health and Care Excellence was not useful for diagnosing asthma in children and adolescents.
Physicians can differentiate between benign and malignant pulmonary nodules, but do not consistently follow guideline-based recommendations when selecting the next diagnostic test.
Clinical symptoms of pneumonia should be identified quickly in pediatric patients to prevent inappropriate therapy.
Comparative measures of inspiratory vs expiratory volumes show a penumbra of lung tissue at higher risk of damage from existing COPD.
A retrospective analysis demonstrated that the ratio of left to right ventricular end-diastolic pressures can predict outcomes in patients with PH.
A study of 65 patients examined the efficacy of using serum periostin as a biomarker for asthma with comorbid upper airway disease.
Fractional exhaled nitric oxide levels directly correlated to subclinical pulmonary disease activity in children with systemic lupus erythematosus.
Researchers simultaneously examined overnight polysomnography and patch recordings to determine the efficacy of the SomnaPatch.
Nearly 37% of patients with hypoventilation were diagnosed with uncontrolled hypothyroidism, and were more likely to present with hypertension and heart failure.
Apnea-hypopnea index concluded that hematocrit levels and presene of erthrocytosis are not associated with OSA.
Rules integrating signs, symptoms, CRP can diagnose acute rhinosinusitis, bacterial rhinosinusitis
Researchers examined the indications, diagnostic accuracy, duration, and clinical impact of point-of-care lung sonography.
Chest CT is not currently part of recommended routine COPD care.
In patients with chronic hypersensitivity pneumonitis, several parenchymal features on CT correlate with mortality and rapid disease progression, including honeycombing and reticular pattern.
New criteria by the American College of Radiology detail appropriateness of various imaging techniques for suspected pulmonary hypertension.
In tuberculosis-endemic areas, computers with deep learning capabilities can be trained to detect the disease in regions that have no radiologists.
The most recent ERS guideline includes significant changes from prior recommendations in an effort to accommodate newer delivery devices.
Computed tomography-derived pulmonary artery-to-aorta ratio can predict pulmonary artery pressure and survival in patients with idiopathic pulmonary fibrosis.
Researchers examined nearly 3000 men and women to determine the relationship between restrictive spirometry pattern, reduced FVC, and arterial stiffness.
Molecular point-of-care testing for viruses led to more patients receiving single or brief doses of antibiotics without any evidence of increased harm.
Lung ultrasounds present an effective alternative to diagnosing pneumonia.