Diagnostics

Improving Risk Stratification, Diagnostic Accuracy in PAH With Cardiopulmonary Exercise Testing

Improving Risk Stratification, Diagnostic Accuracy in PAH With Cardiopulmonary Exercise Testing

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Cardiopulmonary exercise testing can be an important diagnostic and prognostic tool in pulmonary arterial hypertension.

Sarcoidosis Diagnostic Score Enhances Disease Diagnosis

Sarcoidosis Diagnostic Score Enhances Disease Diagnosis

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A Sarcoidosis Diagnostic Score tool was developed by comparing data from individuals with biopsy-confirmed sarcoidosis with that of individuals who did not have sarcoidosis.

Ability of Clinical Scores to Detect Severe Hypoxemic Obstructive Sleep Apnea

Ability of Clinical Scores to Detect Severe Hypoxemic Obstructive Sleep Apnea

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Of the 4 clinical scores used to predict the occurrence of hypoxemic episodes in patients with severe obstructive sleep apnea, DES-OSA appears to be the most effective.

Brain Natriuretic Peptide Shows Promise as Biomarker in Group 1 PAH

Brain Natriuretic Peptide Shows Promise as Biomarker in Group 1 PAH

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There was a significant relationship between brain natriuretic peptide levels and mortality in patients with group 1 pulmonary arterial hypertension.

Early Flow Cytometry Predictive of Clinical Deterioration in Sepsis

Early Flow Cytometry Predictive of Clinical Deterioration in Sepsis

Increased circulating immature granulocytes at the acute phase of sepsis are linked to clinical worsening, especially when associated with T-cell lymphopenia.

PAH-SYMPACT<sup>®</sup>: A Reliable Instrument for PAH Symptom Assessment

PAH-SYMPACT®: A Reliable Instrument for PAH Symptom Assessment

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The Pulmonary Arterial Hypertension-Symptoms and Impact questionnaire has good psychometric properties and can be administered in clinical practice.

Egg-and-Banana Sign Has High Specificity for Pulmonary Hypertension Diagnosis

Egg-and-Banana Sign Has High Specificity for Pulmonary Hypertension Diagnosis

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The "egg-and-banana" sign is a valid computed tomography marker of pulmonary hypertension.

Pediatric Pneumonia: Sensitivity of Lung Ultrasound vs Chest Radiography

Pediatric Pneumonia: Sensitivity of Lung Ultrasound vs Chest Radiography

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Lung ultrasound was more effective in diagnosing pediatric community-acquired pneumonia than chest radiography.

Pulmonary Function Testing Detects Distinct Phenotypes in Bronchopulmonary Dysplasia

Pulmonary Function Testing Detects Distinct Phenotypes in Bronchopulmonary Dysplasia

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Infant pulmonary function testing detected 3 distinct phenotypes in severe bronchopulmonary dysplasia.

YEARS Criteria in Pulmonary Embolism Evaluation May Reduce Need for Imaging

YEARS Criteria in Pulmonary Embolism Evaluation May Reduce Need for Imaging

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D-dimer test adjustment based on pretest probability results may be a safe option to reduce the need for imaging during evaluation for pulmonary embolism.

Sleep Apnea Diagnosis in Heart Failure Using Portable Monitor

Sleep Apnea Diagnosis in Heart Failure Using Portable Monitor

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Portable sleep monitoring may accurately diagnose sleep apnea in patients who are hospitalized with heart failure.

Assessing Depression Following Inpatient COPD Rehabilitation

Assessing Depression Following Inpatient COPD Rehabilitation

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PHQ-9 and PHQ-2 show factorial validity, invariance, and reliability for measuring depression in patients with chronic obstructive pulmonary disease.

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

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Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

Low-Dose CT May Modify Pneumonia Diagnosis in Elderly Patients

Low-Dose CT May Modify Pneumonia Diagnosis in Elderly Patients

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Low-dose computed tomography may assist clinicians in modifying diagnosis of elderly patients who are admitted with suspected pneumonia.

Expert Consensus on Chronic Hypersensitivity Pneumonitis Diagnostic Criteria

Expert Consensus on Chronic Hypersensitivity Pneumonitis Diagnostic Criteria

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Experts in interstitial lung disease identified 18 items of importance for diagnosing chronic hypersensitivity pneumonitis.

Predictive Value of Idiopathic PAH Risk Assessment Using Comorbidities, Age

Predictive Value of Idiopathic PAH Risk Assessment Using Comorbidities, Age

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Ischemic heart disease and kidney dysfunction were identified as 2 comorbidities that may affect outcomes in idiopathic pulmonary arterial hypertension.

A Potential Algorithm for Diagnosing Cavitary Lung Diseases

A Potential Algorithm for Diagnosing Cavitary Lung Diseases

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Researchers developed an algorithmic approach to diagnosing lung cavitary diseases.

COPD Risk Predicted by Large Airway Dimensions on Computed Tomography

COPD Risk Predicted by Large Airway Dimensions on Computed Tomography

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Greater Pi10 was associated with incident spirometry-defined chronic obstructive pulmonary disease in a general population-based sample without clinical lung disease.

Pulmonary Hypertension Outcomes Predicted by NT-pro BNP

Pulmonary Hypertension Outcomes Predicted by NT-pro BNP

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N-terminal-pro brain natriuretic peptide may be a useful biomarker for both mortality and respiratory exacerbations in pediatric patients with pulmonary hypertension.

Simple Lung Function Tests in Primary Care Help ID Early COPD

Simple Lung Function Tests in Primary Care Help ID Early COPD

Peak flow meter, microspirometry are optimal, with full spirometry for positive results.

Inflammatory Markers in CAP Influenced by Time From Symptom Onset to Presentation

Inflammatory Markers in CAP Influenced by Time From Symptom Onset to Presentation

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Differences in serum inflammatory markers may exist between patients with community-acquired pneumonia who present within the first 48 hours of symptom onset vs those who present later.

Newer Rapid Influenza Tests Better at Ruling In Influenza

Newer Rapid Influenza Tests Better at Ruling In Influenza

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Further research on rapid tests is warranted, as industry-sponsored research tends to favor the industry's product and affects how physicians practice medicine.

Pulmonary Hypertension With HFpEF Mortality Predicted by Hemodynamic Markers

Pulmonary Hypertension With HFpEF Mortality Predicted by Hemodynamic Markers

The hemodynamic parameters predict mortality and cardiac hospitalization in patients with heart failure with preserved ejection fraction.

Comparing Diagnostic Imaging for Community-Acquired Pneumonia

Comparing Diagnostic Imaging for Community-Acquired Pneumonia

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Adults with community-acquired pneumonia that is visualized on CT scan but not on concurrent chest radiograph have similar pathogens, disease severity, and outcomes as patients who had pneumonia confirmed via chest radiograph.

Pneumonia-Induced Acute Lung Failure: Angiopoietin-2 Levels May Predict Severity

Pneumonia-Induced Acute Lung Failure: Angiopoietin-2 Levels May Predict Severity

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Interventional reduction of the angiopoietin-1/angiopoietin-2 ratio may provide therapeutic perspective for prevention of acute lung injury in pneumonia.

Routine Chest Radiography After US-Guided CVC Insertion Often Unnecessary

Routine Chest Radiography After US-Guided CVC Insertion Often Unnecessary

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A routine chest radiograph after ultrasound-guided central venous catheter insertion is now considered costly and unnecessary.

Claims-Based Algorithms for Pulmonary Arterial Hypertension Developed

Claims-Based Algorithms for Pulmonary Arterial Hypertension Developed

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Patients with pulmonary arterial hypertension may be better identified through a claims-based algorithm that includes ICD-9-CM codes, specific pulmonary arterial hypertension medications, echocardiography, and right heart catheterization.

Specific COPD Questionnaire Cutoff Threshold May Identify More Symptomatic Patients

Specific COPD Questionnaire Cutoff Threshold May Identify More Symptomatic Patients

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The Clinical COPD Questionnaire cutoff point of 1.4 demonstrated a better agreement with other COPD measures in patients with more symptomatic disease.

Emphysema Threshold on CT Imaging May Have Predictive Value for COPD

Emphysema Threshold on CT Imaging May Have Predictive Value for COPD

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Patients with chronic obstructive pulmonary disease with 5% emphysema based on thoracic computed tomography (CT) imaging may be at a greater risk for poor outcomes.

Benign Lung Nodules Identified Using Proteomic Biomarker

Benign Lung Nodules Identified Using Proteomic Biomarker

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An integrated proteomic classifier accurately identified benign lung nodules when used in patients with a pretest probability of malignancy ≤50%.

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