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Overcoming Challenges to Create a Universal Influenza Vaccine

Overcoming Challenges to Create a Universal Influenza Vaccine

Researchers from the National Institute of Allergy and Infectious Diseases are working to develop a universal influenza vaccine.

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Strain Selection for Annual Influenza Vaccines Should Consider Preexisting Immunity

Strain Selection for Annual Influenza Vaccines Should Consider Preexisting Immunity

Repeated exposure to the influenza virus affects antibody quantity and quality, and strains selected for seasonal vaccines may not provide coverage sufficient for individuals frequently infected and/or vaccinated.

Statins Increase Risk for Medically Attended Acute Respiratory Illness

Statins Increase Risk for Medically Attended Acute Respiratory Illness

Elderly patients who have been inoculated with the influenza vaccine and who also use a statin are at a greater risk for medically attended acute respiratory illness.

Novel Intranasal Influenza Vaccine Shows Tolerability, Safety, and High Immune Response

Novel Intranasal Influenza Vaccine Shows Tolerability, Safety, and High Immune Response

NasoVAX, an adenovirus-based intranasal flu vaccine, shows tolerability, safety, and higher cellular immune response compared to an injectable vaccine.

Baloxavir Marboxil Safe and Effective for High-Risk Influenza

Baloxavir Marboxil Safe and Effective for High-Risk Influenza

When compared to placebo, baloxavir marboxil was associated with reduced risk of influenza complications and faster recovery.

Early Oseltamivir Use Linked to Clinical Benefits in Influenza Complicating ARDS

Early Oseltamivir Use Linked to Clinical Benefits in Influenza Complicating ARDS

Patients with acute respiratory distress syndrome and confirmed influenza diagnosis treated ≤6 hours with oseltamivir had reduced length of hospital stay and a lower rate of mortality.

Variations in Influenza Vaccination Coverage Among Healthcare Employees Reported

Variations in Influenza Vaccination Coverage Among Healthcare Employees Reported

Wide variations in influenza vaccine coverage have been noted across healthcare personnel based on occupation and worksite.

80,000 Americans Died From Influenza Over Last Year

80,000 Americans Died From Influenza Over Last Year

The 2017 to 2018 flu strains hit the very young and elderly especially hard.

Is Mandatory Genetic Testing for Influenza Infection Variants Ethical?

Is Mandatory Genetic Testing for Influenza Infection Variants Ethical?

Mandatory genetic testing may also constitute an undue threat to employee autonomy and privacy.

Active Choice Intervention Tied to Increase in Flu Shot Rates

Active Choice Intervention Tied to Increase in Flu Shot Rates

Vaccination rates decreased throughout the day; with intervention, there was a similar increase throughout day.

Influenza Caused Emirates Flight to Be Briefly Quarantined at JFK

Influenza Caused Emirates Flight to Be Briefly Quarantined at JFK

New York City health officials say passengers had influenza or other common cold viruses.

Coadjuvant Corticosteroids in Influenza Pneumonia Increases ICU Mortality

Coadjuvant Corticosteroids in Influenza Pneumonia Increases ICU Mortality

Corticosteroids should not be used concomitantly with antiviral therapy in patients with influenza pneumonia.

AAP Issues Updated Influenza Vaccine Recommendations

AAP Issues Updated Influenza Vaccine Recommendations

According to the Centers for Disease Control and Prevention (CDC), the 2017-2018 flu season was one of the most severe - excluding pandemics - on record.

Baloxavir Superior to Placebo for Alleviating Flu Symptoms

Baloxavir Superior to Placebo for Alleviating Flu Symptoms

Baloxavir had a median time to alleviation of symptoms vs placebo, and a similar alleviation time as oseltamivir.

Influenza an Independent Risk Factor for Invasive Pulmonary Aspergillosis

Influenza an Independent Risk Factor for Invasive Pulmonary Aspergillosis

Influenza proved to be an independent risk factor for invasive pulmonary aspergillosis.

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

CDC: Updated Influenza Vaccination Recommendations for 2018-2019

In general, routine annual vaccination is recommended for all patients ≥6 months of age who have no contraindications.

Flu Vaccine Reduces Mortality in Rheumatoid Arthritis

Flu Vaccine Reduces Mortality in Rheumatoid Arthritis

Hospitalization risk was also reduced for RA patients who received influenza vaccination.

Inappropriate Antibiotic Prescriptions Highest Among Urgent Care Facilities

Inappropriate Antibiotic Prescriptions Highest Among Urgent Care Facilities

Inappropriate antibiotic prescriptions were highest among urgent care facilities (45.7%), with emergency departments (24.6%), medical offices (17.0%), and retail clinics (14.4%) following.

H1N1 Immune Priming and Egg-Adaptation Affect Antibody Responses After Vaccination

H1N1 Immune Priming and Egg-Adaptation Affect Antibody Responses After Vaccination

Immune priming with seasonal H1N1 viruses earlier in life and egg-adaptation in vaccines can impact antibody responses following influenza vaccination.

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Most children who died of pneumococcus and Haemophilus influenzae type b presented with pneumonia.

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