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Lung Cancer Imaging in Asymptomatic Patients: To Screen or Not to Screen?

Lung Cancer Imaging in Asymptomatic Patients: To Screen or Not to Screen?

Although screening for lung cancer with low-dose computed tomography has demonstrated a reduction in mortality, some experts say the benefits do not outweigh the potential harms.

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Integrated Classifier Identifies Benign Lung Nodules

Integrated Classifier Identifies Benign Lung Nodules

Classifier integrates relative abundance of 2 plasma proteins with clinical risk prediction model for lung nodules.

Vizimpro Approved as First-Line Treatment for EGFR-Mutated Metastatic NSCLC

Vizimpro Approved as First-Line Treatment for EGFR-Mutated Metastatic NSCLC

The approval was based on data from the ARCHER 1050 open-label, active controlled study which randomized patients with unresectable, metastatic NSCLC to treatment with either dacomitinib (N=227) or gefitinib (N=225).

Salvage Therapy for Recurrent SABR-Treated Early-Stage NSCLC Increases Survival

Salvage Therapy for Recurrent SABR-Treated Early-Stage NSCLC Increases Survival

Salvage treatment for recurrence of early-stage non-small cell lung cancer after initial treatment with stereotactic ablative radiotherapy improved patient survival.

RET Inhibitor Gets Breakthrough Tx Status for NSCLC, Medullary Thyroid Cancer

RET Inhibitor Gets Breakthrough Tx Status for NSCLC, Medullary Thyroid Cancer

LOXO-292 is being evaluated in the ongoing Phase 1/2 LIBRETTO-001 clinical trial.

Poor, Non-English Speaking Cancer Patients Need Support

Poor, Non-English Speaking Cancer Patients Need Support

Serving patients' specific needs, such as referral to socioeconomic support, can improve care.

High-Quality Diet Linked to Lower Mortality in Cancer Survivors

High-Quality Diet Linked to Lower Mortality in Cancer Survivors

High-quality diet linked to reduced risk of overall and cancer-specific mortality vs poor-quality diet.

Poor Shared Decision Making for Lung Cancer Screening

Poor Shared Decision Making for Lung Cancer Screening

Physicians universally recommended lung cancer screening and rarely discuss harms.

Early CT Detection of Small Cell Lung Cancer Does Not Improve Survival Rates

Early CT Detection of Small Cell Lung Cancer Does Not Improve Survival Rates

Screening for small cell lung cancer using low-dose computed tomography had no effect on outcomes for patients.

Lung Cancer Imaging in Asymptomatic Patients: To Screen or Not to Screen?

Lung Cancer Imaging in Asymptomatic Patients: To Screen or Not to Screen?

Although screening for lung cancer with low-dose computed tomography has demonstrated a reduction in mortality, some experts say the benefits do not outweigh the potential harms.

Racial Disparities in Surgical Treatment of Lung Cancer

Racial Disparities in Surgical Treatment of Lung Cancer

As lung cancer screening disseminates into clinical practice, efforts designed to target black men should be prioritized.

Keytruda With Pemetrexed + Platinum Chemotherapy OK'd for Nonsquamous NSCLC

Keytruda With Pemetrexed + Platinum Chemotherapy OK'd for Nonsquamous NSCLC

The median OS was not reached at the time of the data cut-off in the pembrolizumab plus chemotherapy arm and was 11.3 months for those in the chemotherapy arm.

Opdivo Approved to Treat Metastatic Small Cell Lung Cancer

Opdivo Approved to Treat Metastatic Small Cell Lung Cancer

Data showed that 12% responded to treatment based on assessment by a Blinded Independent Central Review, regardless of PD-L1 expression; 11% had a partial response, and 1 patient had a complete response (0.9%).

Broad Genetic Testing for NSCLC May Not Improve Survival

Broad Genetic Testing for NSCLC May Not Improve Survival

Compared with routine genetic testing, there was no improvement in unadjusted mortality rate in non-small cell lung cancer.

Disparities Remain in Prevalence of Cancer Screening Tests

Disparities Remain in Prevalence of Cancer Screening Tests

From 2000 to 2015, individuals without insurance or usual care were less likely to have undergone cancer screening.

Biomarker Panel May Improve Lung Cancer Risk Assessment

Biomarker Panel May Improve Lung Cancer Risk Assessment

Risk score based on panel of four circulating protein biomarkers.

Lurbinectedin Gains Orphan Drug Status for Small Cell Lung Cancer

Lurbinectedin Gains Orphan Drug Status for Small Cell Lung Cancer

A Phase 2 multicenter trial examined the safety and efficacy of lurbinectedin in several types of advanced solid tumors, including SCLC.

Nurse Navigators Can Help to Improve Oncology Care

Nurse Navigators Can Help to Improve Oncology Care

Nurse navigators include registered nurses and licensed practical nurses who work together in pairs

Lay Health Workers Can Improve End-of-Life Cancer Care

Lay Health Workers Can Improve End-of-Life Cancer Care

Incorporating lay health workers into cancer care increases goals-of-care documentation and patient satisfaction.

Aldehydes Dominant Carcinogen in Tobacco Smoke

Aldehydes Dominant Carcinogen in Tobacco Smoke

Aldehydes act by inducing DNA damage and inhibiting DNA repair.

Lung Cancer Incidence in HIV Remains High Years After Smoking Cessation

Lung Cancer Incidence in HIV Remains High Years After Smoking Cessation

The incidence of lung cancer remains increased 5 years after smoking cessation.

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