Lung Cancer

New Assays May Detect Early Lung Cancer in Blood

New Assays May Detect Early Lung Cancer in Blood

Targeted sequencing, whole-genome sequencing, and whole-genome bisulfite sequencing showed potential for detecting lung cancer.

Pembrolizumab Superior for Initial Treatment of Advanced NSCLC

Pembrolizumab Superior for Initial Treatment of Advanced NSCLC

Pembrolizumab improved overall survival vs chemotherapy regardless of the programmed death ligand 1 tumor proportion score.

Indeterminate Pulmonary Nodules Characterized by CT-Based Radiomic Classifier

Indeterminate Pulmonary Nodules Characterized by CT-Based Radiomic Classifier

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A total of 8 quantitative radiologic features were used to characterize indeterminate screen-detected lung nodules.

Alimta Labeling Updated to Include Combo Treatment for NSCLC

Alimta Labeling Updated to Include Combo Treatment for NSCLC

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Merck initially gained accelerated approval for Keytruda with Alimta and carboplatin in May 2017.

Prediction Tool Helps Tailor Lung Cancer Screening to Patients

Prediction Tool Helps Tailor Lung Cancer Screening to Patients

Researchers created a web-based decision tool to facilitate personalized discussions regarding lung cancer screening.

Lung Cancer Incidence Higher in Young Women Than Young Men

Lung Cancer Incidence Higher in Young Women Than Young Men

Researchers examined nationwide population-based incidence of lung cancer according to sex, race or ethnic group, age group, birth year, and calendar period of diagnosis.

Bioengineering Feasible for Airway Reconstruction

Bioengineering Feasible for Airway Reconstruction

Bioengineered tracheal and bronchial reconstruction was conducted using stented aortic matrices.

Few Eligible Smokers Had Lung Cancer Screening in 2016

Few Eligible Smokers Had Lung Cancer Screening in 2016

The most eligible smokers were populated in South, which had most screening sites but the low screening rates

Risk Models Help Select Ever Smokers for Lung Cancer Screening

Risk Models Help Select Ever Smokers for Lung Cancer Screening

Four models were well-calibrated and had higher areas under the curve than 5 models that overestimated lung cancer risk.

CKAP4 Is Novel Serodiagnostic Marker for Lung Cancer

CKAP4 Is Novel Serodiagnostic Marker for Lung Cancer

Serum CKAP4 levels of lung cancer patients were significantly higher than those of healthy controls.

Cancer Incidences and Burden Expected to Shift in HIV-Positive

Cancer Incidences and Burden Expected to Shift in HIV-Positive

Prostate and lung cancer expected to emerge as the most common types by 2030.

Clinical Upstaging of NSCLC Seen With Each Progressive Week

Clinical Upstaging of NSCLC Seen With Each Progressive Week

For clinical stage 1 non-small-cell lung cancer, 21.7% of patients upstaged after 1 week and 31.5% after 8 weeks.

Polypharmacy More Likely for Cancer Survivors

Polypharmacy More Likely for Cancer Survivors

More cancer survivors prescribed 5 or more unique medications, including medications with abuse potential.

A Potential Algorithm for Diagnosing Cavitary Lung Diseases

A Potential Algorithm for Diagnosing Cavitary Lung Diseases

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Researchers developed an algorithmic approach to diagnosing lung cavitary diseases.

Adjuvant Pembrolizumab Beneficial in Metastatic NSCLC

Adjuvant Pembrolizumab Beneficial in Metastatic NSCLC

Nivolumab plus ipilimumab linked to better survival in NSCLC with high tumor mutational burden.

Most Patients Are Unaware of Cancer Drug Shortages

Most Patients Are Unaware of Cancer Drug Shortages

Majority of patients say they want to know about even minor consequences of cancer drug substitutions.

Dacomitinib Granted Priority Review for NSCLC With EGFR-Activating Mutations

Dacomitinib Granted Priority Review for NSCLC With EGFR-Activating Mutations

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Dacomitinib is a pan-human epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor.

Lag in Progress Against Lung Cancer Mortality in Midwest, Appalachia

Lag in Progress Against Lung Cancer Mortality in Midwest, Appalachia

Findings based on rates in women vs steady decline seen nationally.

Benign Lung Nodules Identified Using Proteomic Biomarker

Benign Lung Nodules Identified Using Proteomic Biomarker

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An integrated proteomic classifier accurately identified benign lung nodules when used in patients with a pretest probability of malignancy ≤50%.

Lung Cancer Risk May Be Predicted by Frequency of COPD Exacerbations

Lung Cancer Risk May Be Predicted by Frequency of COPD Exacerbations

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Independent predictive factors of lung cancer in chronic obstructive pulmonary disease may include frequency of exacerbations, in addition to airflow obstruction and visual emphysema.

COPD, Respiratory Symptoms Associated With "Western" Diet

COPD, Respiratory Symptoms Associated With "Western" Diet

Researchers used data from the Atherosclerosis Risk in Communities Study to assess associations between dietary pattern and pulmonary assessments.

Infused Chemotherapy Trends During 10-Year Period

Infused Chemotherapy Trends During 10-Year Period

During a 10-year period, there was an increase in the rate of commercially insured patients receiving infused chemotherapy in hospital outpatient departments.

Exercise May Improve Quality of Life in Lung Cancer

Exercise May Improve Quality of Life in Lung Cancer

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Study examines increased physical activity may lower the risk for several cancers and may be beneficial for improving quality of life.

Lung Cancer Screening: Updated Guidelines From CHEST

Lung Cancer Screening: Updated Guidelines From CHEST

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A CHEST expert panel has released updated guidelines for lung cancer screening.

Lung Cancer Postoperative Complications Reduced With Preoperative Exercise

Lung Cancer Postoperative Complications Reduced With Preoperative Exercise

Patients who underwent lung resections had reduced postoperative complication rates when they participated in preoperative exercise.

Early-Stage Non-Small Cell Lung Cancer Mortality With Surgery vs Radiotherapy

Early-Stage Non-Small Cell Lung Cancer Mortality With Surgery vs Radiotherapy

Mortality rates are higher after surgery vs stereotactic body radiotherapy for patients with early non-small-cell lung cancer.

Lung Cancer Screening Requires Effective Risk Stratification

Lung Cancer Screening Requires Effective Risk Stratification

Lung cancer screening is more effective and efficient for high-risk individuals.

Lung Cancer Survival May Be Predicted by BMI and Age

Lung Cancer Survival May Be Predicted by BMI and Age

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Younger age and higher body mass index may be positive predictors of progression-free survival in patients with squamous cell carcinoma of the lung.

Small Cell Lung Cancer: Barriers to Chemotherapy, Radiation

Small Cell Lung Cancer: Barriers to Chemotherapy, Radiation

Lack of insurance correlated with a reduced likelihood of chemotherapy and radiation therapy for small cell lung cancer.

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