Salvage treatment for recurrence of early-stage non-small cell lung cancer after initial treatment with stereotactic ablative radiotherapy improved patient survival.
LOXO-292 is being evaluated in the ongoing Phase 1/2 LIBRETTO-001 clinical trial.
Serving patients' specific needs, such as referral to socioeconomic support, can improve care.
High-quality diet linked to reduced risk of overall and cancer-specific mortality vs poor-quality diet.
Physicians universally recommended lung cancer screening and rarely discuss harms.
Screening for small cell lung cancer using low-dose computed tomography had no effect on outcomes for patients.
Although screening for lung cancer with low-dose computed tomography has demonstrated a reduction in mortality, some experts say the benefits do not outweigh the potential harms.
As lung cancer screening disseminates into clinical practice, efforts designed to target black men should be prioritized.
The median OS was not reached at the time of the data cut-off in the pembrolizumab plus chemotherapy arm and was 11.3 months for those in the chemotherapy arm.
Data showed that 12% responded to treatment based on assessment by a Blinded Independent Central Review, regardless of PD-L1 expression; 11% had a partial response, and 1 patient had a complete response (0.9%).
Compared with routine genetic testing, there was no improvement in unadjusted mortality rate in non-small cell lung cancer.
From 2000 to 2015, individuals without insurance or usual care were less likely to have undergone cancer screening.
Risk score based on panel of four circulating protein biomarkers.
A Phase 2 multicenter trial examined the safety and efficacy of lurbinectedin in several types of advanced solid tumors, including SCLC.
Nurse navigators include registered nurses and licensed practical nurses who work together in pairs
Incorporating lay health workers into cancer care increases goals-of-care documentation and patient satisfaction.
Aldehydes act by inducing DNA damage and inhibiting DNA repair.
The incidence of lung cancer remains increased 5 years after smoking cessation.
ICU and hospital mortality were lower for patients with cancer vs those without cancer.
Standardized definition and guidance on estimation may facilitate understanding of cancer overdiagnosis.
Post-traumatic stress symptoms were also linked to lower risk of readmission in hospitalized patients with cancer.
Awake video-assisted thoracoscopic surgery was safe and feasible in some patients with poor lung function and lung cancer.
Targeted sequencing, whole-genome sequencing, and whole-genome bisulfite sequencing showed potential for detecting lung cancer.
Pembrolizumab improved overall survival vs chemotherapy regardless of the programmed death ligand 1 tumor proportion score.
A total of 8 quantitative radiologic features were used to characterize indeterminate screen-detected lung nodules.
Merck initially gained accelerated approval for Keytruda with Alimta and carboplatin in May 2017.
Researchers created a web-based decision tool to facilitate personalized discussions regarding lung cancer screening.
Researchers examined nationwide population-based incidence of lung cancer according to sex, race or ethnic group, age group, birth year, and calendar period of diagnosis.
Bioengineered tracheal and bronchial reconstruction was conducted using stented aortic matrices.
The most eligible smokers were populated in South, which had most screening sites but the low screening rates