Lung Cancer

Salvage Therapy for Recurrent SABR-Treated Early-Stage NSCLC Increases Survival

Salvage Therapy for Recurrent SABR-Treated Early-Stage NSCLC Increases Survival

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Salvage treatment for recurrence of early-stage non-small cell lung cancer after initial treatment with stereotactic ablative radiotherapy improved patient survival.

RET Inhibitor Gets Breakthrough Tx Status for NSCLC, Medullary Thyroid Cancer

RET Inhibitor Gets Breakthrough Tx Status for NSCLC, Medullary Thyroid Cancer

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LOXO-292 is being evaluated in the ongoing Phase 1/2 LIBRETTO-001 clinical trial.

Poor, Non-English Speaking Cancer Patients Need Support

Poor, Non-English Speaking Cancer Patients Need Support

Serving patients' specific needs, such as referral to socioeconomic support, can improve care.

High-Quality Diet Linked to Lower Mortality in Cancer Survivors

High-Quality Diet Linked to Lower Mortality in Cancer Survivors

High-quality diet linked to reduced risk of overall and cancer-specific mortality vs poor-quality diet.

Poor Shared Decision Making for Lung Cancer Screening

Poor Shared Decision Making for Lung Cancer Screening

Physicians universally recommended lung cancer screening and rarely discuss harms.

Early CT Detection of Small Cell Lung Cancer Does Not Improve Survival Rates

Early CT Detection of Small Cell Lung Cancer Does Not Improve Survival Rates

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Screening for small cell lung cancer using low-dose computed tomography had no effect on outcomes for patients.

Lung Cancer Imaging in Asymptomatic Patients: To Screen or Not to Screen?

Lung Cancer Imaging in Asymptomatic Patients: To Screen or Not to Screen?

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Although screening for lung cancer with low-dose computed tomography has demonstrated a reduction in mortality, some experts say the benefits do not outweigh the potential harms.

Racial Disparities in Surgical Treatment of Lung Cancer

Racial Disparities in Surgical Treatment of Lung Cancer

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As lung cancer screening disseminates into clinical practice, efforts designed to target black men should be prioritized.

Keytruda With Pemetrexed + Platinum Chemotherapy OK'd for Nonsquamous NSCLC

Keytruda With Pemetrexed + Platinum Chemotherapy OK'd for Nonsquamous NSCLC

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The median OS was not reached at the time of the data cut-off in the pembrolizumab plus chemotherapy arm and was 11.3 months for those in the chemotherapy arm.

Opdivo Approved to Treat Metastatic Small Cell Lung Cancer

Opdivo Approved to Treat Metastatic Small Cell Lung Cancer

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Data showed that 12% responded to treatment based on assessment by a Blinded Independent Central Review, regardless of PD-L1 expression; 11% had a partial response, and 1 patient had a complete response (0.9%).

Broad Genetic Testing for NSCLC May Not Improve Survival

Broad Genetic Testing for NSCLC May Not Improve Survival

Compared with routine genetic testing, there was no improvement in unadjusted mortality rate in non-small cell lung cancer.

Disparities Remain in Prevalence of Cancer Screening Tests

Disparities Remain in Prevalence of Cancer Screening Tests

From 2000 to 2015, individuals without insurance or usual care were less likely to have undergone cancer screening.

Biomarker Panel May Improve Lung Cancer Risk Assessment

Biomarker Panel May Improve Lung Cancer Risk Assessment

Risk score based on panel of four circulating protein biomarkers.

Lurbinectedin Gains Orphan Drug Status for Small Cell Lung Cancer

Lurbinectedin Gains Orphan Drug Status for Small Cell Lung Cancer

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A Phase 2 multicenter trial examined the safety and efficacy of lurbinectedin in several types of advanced solid tumors, including SCLC.

Nurse Navigators Can Help to Improve Oncology Care

Nurse Navigators Can Help to Improve Oncology Care

Nurse navigators include registered nurses and licensed practical nurses who work together in pairs

Lay Health Workers Can Improve End-of-Life Cancer Care

Lay Health Workers Can Improve End-of-Life Cancer Care

Incorporating lay health workers into cancer care increases goals-of-care documentation and patient satisfaction.

Aldehydes Dominant Carcinogen in Tobacco Smoke

Aldehydes Dominant Carcinogen in Tobacco Smoke

Aldehydes act by inducing DNA damage and inhibiting DNA repair.

Lung Cancer Incidence in HIV Remains High Years After Smoking Cessation

Lung Cancer Incidence in HIV Remains High Years After Smoking Cessation

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The incidence of lung cancer remains increased 5 years after smoking cessation.

Initial Outcomes No Worse for Surgical ICU Patients With Cancer

Initial Outcomes No Worse for Surgical ICU Patients With Cancer

ICU and hospital mortality were lower for patients with cancer vs those without cancer.

Exploring Overdiagnosis in Cancer Screening

Exploring Overdiagnosis in Cancer Screening

Standardized definition and guidance on estimation may facilitate understanding of cancer overdiagnosis.

In Cancer, PTSD May Increase Symptom Burden

In Cancer, PTSD May Increase Symptom Burden

Post-traumatic stress symptoms were also linked to lower risk of readmission in hospitalized patients with cancer.

Awake Video-Assisted Thoracoscopic Surgery Safe Option in Lung Cancer

Awake Video-Assisted Thoracoscopic Surgery Safe Option in Lung Cancer

Awake video-assisted thoracoscopic surgery was safe and feasible in some patients with poor lung function and lung cancer.

New Assays May Detect Early Lung Cancer in Blood

New Assays May Detect Early Lung Cancer in Blood

Targeted sequencing, whole-genome sequencing, and whole-genome bisulfite sequencing showed potential for detecting lung cancer.

Pembrolizumab Superior for Initial Treatment of Advanced NSCLC

Pembrolizumab Superior for Initial Treatment of Advanced NSCLC

Pembrolizumab improved overall survival vs chemotherapy regardless of the programmed death ligand 1 tumor proportion score.

Indeterminate Pulmonary Nodules Characterized by CT-Based Radiomic Classifier

Indeterminate Pulmonary Nodules Characterized by CT-Based Radiomic Classifier

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A total of 8 quantitative radiologic features were used to characterize indeterminate screen-detected lung nodules.

Alimta Labeling Updated to Include Combo Treatment for NSCLC

Alimta Labeling Updated to Include Combo Treatment for NSCLC

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Merck initially gained accelerated approval for Keytruda with Alimta and carboplatin in May 2017.

Prediction Tool Helps Tailor Lung Cancer Screening to Patients

Prediction Tool Helps Tailor Lung Cancer Screening to Patients

Researchers created a web-based decision tool to facilitate personalized discussions regarding lung cancer screening.

Lung Cancer Incidence Higher in Young Women Than Young Men

Lung Cancer Incidence Higher in Young Women Than Young Men

Researchers examined nationwide population-based incidence of lung cancer according to sex, race or ethnic group, age group, birth year, and calendar period of diagnosis.

Bioengineering Feasible for Airway Reconstruction

Bioengineering Feasible for Airway Reconstruction

Bioengineered tracheal and bronchial reconstruction was conducted using stented aortic matrices.

Few Eligible Smokers Had Lung Cancer Screening in 2016

Few Eligible Smokers Had Lung Cancer Screening in 2016

The most eligible smokers were populated in South, which had most screening sites but the low screening rates

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