Latest

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Drop in Childhood Pneumococcal, Hib Deaths From 2000 to 2015

Most children who died of pneumococcus and Haemophilus influenzae type b presented with pneumonia.

Viral Testing May Reduce Antibiotic Use in Severe Lower Respiratory Infection

Viral Testing May Reduce Antibiotic Use in Severe Lower Respiratory Infection

Advanced diagnostic platforms to identify viruses can help patients with severe lower respiratory tract infections avoid unnecessary diagnostic testing, reduce antibiotic use, and initiate antiviral therapy.

Is Short-Course Antibiotic Treatment for CAP Effective?

Is Short-Course Antibiotic Treatment for CAP Effective?

To investigate what impact antibiotic treatment duration has on CAP outcomes, researchers from the Warren Alpert Medical School of Brown University conducted a search of various databases for studies comparing the safety and efficacy of treatment regimens lasting ≤6 days (short) and ≥7 days (long).

Type 2 Diabetes Does Not Affect Pneumonia Incidence, Outcomes After Stroke

Type 2 Diabetes Does Not Affect Pneumonia Incidence, Outcomes After Stroke

Investigators examined the incidence and outcomes of pneumonia in patients with acute ischemic stroke and type 2 diabetes.

Priority Review Granted to Novel Oral Influenza Treatment

Priority Review Granted to Novel Oral Influenza Treatment

The New Drug Application for baloxavir marboxil is supported by results from the Phase 3 CAPSTONE-1 study (N=1436) which examined the effects of a single dose of baloxavir marboxil vs placebo or oseltamivir 75mg twice daily for 5 days.

Community-Acquired Pneumonia In-Hospital Deaths Are Not Indicative of Lapse in Care

Community-Acquired Pneumonia In-Hospital Deaths Are Not Indicative of Lapse in Care

Most deaths related to community-acquired pneumonia that occurred at tertiary-case hospitals were not preventable.

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory pathogens were associated with an increased risk for treatment failure in children with asthma exacerbations.

Misuse of Antibiotics Common in Outpatient Acute Respiratory Infections

Misuse of Antibiotics Common in Outpatient Acute Respiratory Infections

The researchers argued that outpatient antibiotic stewardship efforts must be strengthened to eliminate antibiotic treatment for viral upper respiratory infections and acute bronchitis.

PCV13 Reduces Hospitalization for Vaccine-Type Community-Acquired Pneumonia

PCV13 Reduces Hospitalization for Vaccine-Type Community-Acquired Pneumonia

The real-world effectiveness of PCV13 vaccine in preventing hospitalization for vaccine-type community-acquired pneumonia was assessed.

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

Although clinical presentation was similar in both community-acquired pneumonia and non-pneumonia exacerbations, CRP, glucose, and leukocytes were higher in the former vs the latter.

Early Clinical Response With Omadacycline vs Moxifloxacin in CABP

Early Clinical Response With Omadacycline vs Moxifloxacin in CABP

Early clinical response rates were similar across PORT risk class subgroups in patients with community-acquired bacterial pneumonia when treated with omadacycline or moxifloxacin.

Prevnar 13 Linked to Reduced Risk of CAP Hospitalization in Older Patients

Prevnar 13 Linked to Reduced Risk of CAP Hospitalization in Older Patients

PCV13, marketed as Prevnar 13, was evaluated in a test-negative case-control study in real-world conditions where patients were administered pneumococcal vaccination as advised by their healthcare providers.

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

AAP Recommends Shot Over Nasal Spray for 2018-2019 Flu Season

The advisory comes early as physicians are currently placing vaccine orders.

Positive Results Announced for Pleuromutilin Antibiotic in CABP

Positive Results Announced for Pleuromutilin Antibiotic in CABP

In the LEAP 2 study (N=738), patients with moderate CABP received either oral lefamulin 600mg every 12 hours for 5 days or oral moxifloxacin 400mg once daily for 7 days.

Prior Atypical Antipsychotic Use May Increase Mortality Risk in Pneumonia

Prior Atypical Antipsychotic Use May Increase Mortality Risk in Pneumonia

Clinicians should consider these findings when using atypical antipsychotics in patients at risk for pneumonia.

Hypersensitivity Pneumonitis Prevalence in an Insured US Population

Hypersensitivity Pneumonitis Prevalence in an Insured US Population

Researchers have developed a novel algorithm to identify hypersensitivity pneumonitis.

Pediatric Pneumonia: Sensitivity of Lung Ultrasound vs Chest Radiography

Pediatric Pneumonia: Sensitivity of Lung Ultrasound vs Chest Radiography

Lung ultrasound was more effective in diagnosing pediatric community-acquired pneumonia than chest radiography.

Legionella Pneumonia Outcomes Similar in Adults With/Without HIV

Legionella Pneumonia Outcomes Similar in Adults With/Without HIV

Clinical presentation and outcomes in HIV-infected patients with Legionella pneumonia did not differ from patients without HIV infection.

Low-Dose CT May Modify Pneumonia Diagnosis in Elderly Patients

Low-Dose CT May Modify Pneumonia Diagnosis in Elderly Patients

Low-dose computed tomography may assist clinicians in modifying diagnosis of elderly patients who are admitted with suspected pneumonia.

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

Flu Vaccines Have High Impact, Even With Relatively Low Efficacy

A high impact was seen, especially when the vaccine uptake was optimally distributed across age groups.

Sign Up for Free e-newsletters