Tralokinumab Ineffective for Eosinophilic Airway Inflammation in Asthma

Tralokinumab Ineffective for Eosinophilic Airway Inflammation in Asthma

Tralokinumab did not have a significant effect on eosinophilic airway inflammation in moderate to severe asthma that was inadequately controlled on inhaled corticosteroids.

COPD Education Program Improved Patient Knowledge of Disease

COPD Education Program Improved Patient Knowledge of Disease

There was as significant change in Bristol COPD Knowledge Questionnaire scores in patients who received a brief education program at the time of an acute exacerbation of COPD.

Stroke, MI Risk Increased After Severe COPD Exacerbations

Stroke, MI Risk Increased After Severe COPD Exacerbations

Acute COPD exacerbations were associated with an increased risk for myocardial infarction and ischemic stroke.

Viruses not linked to asthma exacerbation severity

Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure.

Immune-Response Cluster in Infant Respiratory Syncytial Virus Linked With Recurrent Wheeze

Immune-Response Cluster in Infant Respiratory Syncytial Virus Linked With Recurrent Wheeze

A nasal immune-response pattern characterized by lower non-interferon antiviral immune response mediators and higher type 2 and type 17 cytokines was significantly associated with recurrent wheeze at 1 year.

Budesonide-formoterol as needed superior to terbutaline in mild asthma: The SYGMA trial

In patients with mild asthma, use of the inhaled combined corticosteroid and beta agonist budesonide-formoterol as needed was superior to terbutaline as needed with respect to electronically recorded weeks of well-controlled asthma.

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Zephyr® Endobronchial Valve EBV® treatment improved FEV1 in patients with heterogeneous emphysema.

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

The inclusion of residual volume-to-total lung capacity ratio may add another dimension to COPD not routinely captured by standard airflow indices that could be predictive of lower maximum exercise capacity.

COPD Triple Therapy Switch to LABA/LAMA May Be Appropriate in Some Patients

COPD Triple Therapy Switch to LABA/LAMA May Be Appropriate in Some Patients

A direct de-escalation from triple therapy to indacaterol/glycopyrronium may be appropriate in patients with infrequent COPD exacerbations.

Ivacaftor Decreases Mortality, Hospitalization in Cystic Fibrosis

Ivacaftor Decreases Mortality, Hospitalization in Cystic Fibrosis

Ivacaftor decreased the risk for death, transplantation, hospitalization, and pulmonary exacerbation in patients with cystic fibrosis.

Various Perinatal Risks Associated With Maternal Asthma Diagnosis

Various Perinatal Risks Associated With Maternal Asthma Diagnosis

Women with a diagnosis of asthma may have a higher risk for preterm birth, and their infants may have an increased risk for perinatal mortality, low birth weight, fetal growth restriction, and asphyxia.

Omalizumab Inhibits Respiratory Reactions During Aspirin Desensitization

Omalizumab Inhibits Respiratory Reactions During Aspirin Desensitization

In patients with aspirin exacerbated respiratory disease, treatment with omalizumab resulted in "clinically silent" aspirin desensitization.

Asthma Exacerbation Risk With As-Needed Budesonide-Formoterol vs Maintenance Budesonide

Asthma Exacerbation Risk With As-Needed Budesonide-Formoterol vs Maintenance Budesonide

Budesonide-formoterol as needed was not inferior compared with budesonide maintenance therapy in terms of severe asthma exacerbation rates, but may be inferior for controlling symptoms.

Greater Use of Tobacco Products Among Youth With Asthma

Greater Use of Tobacco Products Among Youth With Asthma

E-cigarettes are the most commonly used product in middle and high school students with or without asthma.

Effectiveness of Budesonide-Formoterol vs Terbutaline in Asthma Symptom Control

Effectiveness of Budesonide-Formoterol vs Terbutaline in Asthma Symptom Control

There was a 60% lower rate of severe asthma exacerbations in individuals treated with budesonide-formoterol compared with individuals treated with terbutaline as needed.

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

C-Reactive Protein as a Biomarker for CAP in Bronchiectasis

Although clinical presentation was similar in both community-acquired pneumonia and non-pneumonia exacerbations, CRP, glucose, and leukocytes were higher in the former vs the latter.

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

A definition of a pulmonary vascular phenotype of chronic obstructive pulmonary disease has been proposed.

Asthma-Associated Chemicals in Hair Products for Black Women Raise Concerns

Asthma-Associated Chemicals in Hair Products for Black Women Raise Concerns

Chemicals linked with endocrine disruption and asthma identified in hair products used by black women and children.

Budesonide Improved Epithelial Barrier Function in Asthma

Budesonide Improved Epithelial Barrier Function in Asthma

Researchers evaluated barrier dysfunction by exposing viral models to budesonide, montelukast, formoterol, or a combination.

Inhaled Interferon-Beta 1a Does Not Reduce Severe Asthma Exacerbations

Inhaled Interferon-Beta 1a Does Not Reduce Severe Asthma Exacerbations

Inhaled interferon-beta 1 a did not significantly reduce acute asthma exacerbations during respiratory viral infections.

E-Cigarette Use Associated With Increased Risk for COPD

E-Cigarette Use Associated With Increased Risk for COPD

Using e-cigarettes every day or some days increased the likelihood of developing chronic obstructive pulmonary disease.

Longer Hospital Stay, Higher Costs With Unwarranted Antibiotics in Asthma Exacerbations

Longer Hospital Stay, Higher Costs With Unwarranted Antibiotics in Asthma Exacerbations

Longer stay and higher costs were associated with antibiotic administration in adults hospitalized for an asthma exacerbation without documented evidence of a lung infection.

COPD Frequently Misdiagnosed, Undiagnosed in Individuals With or Without HIV

COPD Frequently Misdiagnosed, Undiagnosed in Individuals With or Without HIV

In this study, researchers examined the appropriateness of diagnosis and treatment of chronic obstructive pulmonary disease in individuals with and without HIV.

Morning vs Evening ICS Dosing in Asthma: Efficacies Compared

Morning vs Evening ICS Dosing in Asthma: Efficacies Compared

Inhaled corticosteroids for asthma dosed once daily in the evening appeared to offer some benefit in trough FEV1 and morning peak expiratory flow.

Anxiety, Depression Associated With Poor Self-Perceived Asthma Control

Anxiety, Depression Associated With Poor Self-Perceived Asthma Control

Investigators conducted a prospective survey to examine the association between asthma symptom severity and symptoms of depression and anxiety.

Overweight, Obesity Linked to Asthma Development in Children and Adolescents

Overweight, Obesity Linked to Asthma Development in Children and Adolescents

Overweight or obese children are more likely to develop new onset asthma compared with normal weight controls.

Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma

Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma

Researchers examined the association of timing, frequency, and class of antibiotic use during pregnancy on the development of childhood asthma.

Mortality Rates in Extrafine ICS-Containing vs ICS-Free Medications in COPD

Mortality Rates in Extrafine ICS-Containing vs ICS-Free Medications in COPD

The pooled safety analysis included data from the TRILOGY, TRINITY, and TRIBUTE studies.

Sertraline Not Beneficial for Symptomatic Chronic Breathlessness

Sertraline Not Beneficial for Symptomatic Chronic Breathlessness

Sertraline does not prove to be beneficial for relief of chronic breathlessness.

Incident Diuretic Use May Increase Adverse Events in COPD

Incident Diuretic Use May Increase Adverse Events in COPD

Incident diuretic use was associated with increased rates of respiratory-related morbidity and mortality in older adults with chronic obstructive pulmonary disease.

Efficacy, Safety of Dupilumab in Corticosteroid-Dependent Severe Asthma

Efficacy, Safety of Dupilumab in Corticosteroid-Dependent Severe Asthma

Subcutaneous dupilumab significantly reduced the use of oral corticosteroids in patients with corticosteroid-dependent severe asthma.

Lung Function in Severe Asthma Improved With Benralizumab

Lung Function in Severe Asthma Improved With Benralizumab

Peak expiratory flow increases were greater with benralizumab than placebo in patients with severe eosinophilic asthma.

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Oral contraceptive use in women of reproductive age may increase the risk for lifetime asthma.

Vitamin D Supplementation Improves Asthma Control

Vitamin D Supplementation Improves Asthma Control

In individuals with asthma and vitamin D deficiency, vitamin D supplementation improved asthma control.

Macrolides for Asthma Management: An Updated Review

Macrolides for Asthma Management: An Updated Review

While macrolides had no direct effect on lung function, their use significantly improved asthma control and quality of life in patients with asthma.

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

The study authors examined data obtained from the 2007-2008 National Survey of Children's Health (NSCH) to determine the prevalence, risk factors, as well as the severity of asthma phenotypes.

Most Concerning Med Issues Explored Among Youth With Asthma

Most Concerning Med Issues Explored Among Youth With Asthma

The study authors reported, "The most commonly reported problems by youth were: (a) hard to remember when to take the asthma medication (54%) and (b) hard to use asthma medication at school (34%)."

Feasibility of At-Home Use Injectable Tx for Severe Asthma Assessed

Feasibility of At-Home Use Injectable Tx for Severe Asthma Assessed

Of the total 573 APFS dispensed, 1 malfunctioned and 1 was considered nonfunctional because it was not returned. The study authors also reported that patient-use error only led to 2 unsuccessful at-home administrations.

ICS Therapy May Not Be Enough for Asthma Patients With Elevated Eosinophils

ICS Therapy May Not Be Enough for Asthma Patients With Elevated Eosinophils

The study aimed to determine the association between ICS therapy adherence and the occurrence of asthma exacerbations in patients with high blood eosinophil levels.

Type 2 Biomarkers May Predict Exacerbations in Severe Refractory Asthma

Type 2 Biomarkers May Predict Exacerbations in Severe Refractory Asthma

The positive association between type 2 biomarkers and severe exacerbations in severe refractory asthma may not extend to mild to moderate asthma.

Assessing Depression Following Inpatient COPD Rehabilitation

Assessing Depression Following Inpatient COPD Rehabilitation

PHQ-9 and PHQ-2 show factorial validity, invariance, and reliability for measuring depression in patients with chronic obstructive pulmonary disease.

Low Neighborhood Walkability Increases Risk of Asthma in Kids

Low Neighborhood Walkability Increases Risk of Asthma in Kids

Children living in neighborhoods with low walkability are at increased risk of asthma.

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative care consultation was linked to a reduction in hospital costs for hospitalized adults with serious illness, such as COPD.

Pediatric Asthma Outcomes With Physician Cultural Communication Training

Pediatric Asthma Outcomes With Physician Cultural Communication Training

Physician asthma care education Plus training resulted in improvements in provider confidence, perceived skill in communicating cross culturally, and short-term asthma-specific outcomes.

Asthma Care Program Improves Provider Documentation, Clinical Measures

Asthma Care Program Improves Provider Documentation, Clinical Measures

An asthma care program improved implementation of guidelines as well as provider documentation in 65 community centers in 4 states that serve patients with asthma.

Survival Predictors When Life Support Is Withheld in ICU

Survival Predictors When Life Support Is Withheld in ICU

Survival at 6 months was significantly associated with acute respiratory failure and history of COPD.

Current Smokers With Severe Asthma Distinguished by Sputum Proteomics

Current Smokers With Severe Asthma Distinguished by Sputum Proteomics

Patients with severe asthma who were current smokers were distinguishable from ex-smokers based on their sputum proteomic level of colony stimulating factor 2.

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

A higher proportion of patients with COPD and a blood eosinophil count of ≥0.34×109/L had elevated markers of low-grade systemic inflammation regardless of forced expiratory volume in 1 second.

Children With Status Asthmaticus Do Not Benefit From Magnesium Sulfate

Children With Status Asthmaticus Do Not Benefit From Magnesium Sulfate

Children with status asthmaticus who received magnesium sulfate therapy were on continuous albuterol for a longer duration.

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

Readmission rates were highest during the first 72 hours after admission for an acute exacerbation of chronic obstructive pulmonary disease.

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

Adding olodaterol to tiotropium did not significantly reduce exacerbations in patients with chronic obstructive pulmonary disease as much as researchers had anticipated.

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD overlap linked to higher prevalence of sleep-related symptoms, including difficulty falling asleep and maintaining sleep, early-morning awakening, and excessive daytime sleepiness.

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

The drug consists of fluticasone furoate, an inhaled corticosteroid (ICS), umeclidinium, a long-acting muscarinic antagonist, and vilanterol, a long-acting beta2-adrenergic agonist (LABA), delivered via an Ellipta dry powder inhaler.

Early Child Care Attendance and Asthma, Wheeze Risk: What's the Link?

Early Child Care Attendance and Asthma, Wheeze Risk: What's the Link?

Early child care attendance increased the risk for wheeze in children ≤2 years of age but decreased the risk for asthma in children 3 to 5 years of age.

Transcatheter vs Surgical Aortic Valve Replacement in COPD

Transcatheter vs Surgical Aortic Valve Replacement in COPD

In patients with COPD, transcatheter aortic valve replacement was associated with fewer respiratory-related complications than surgical aortic valve replacement.

Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple therapy with fluticasone furoate, umeclidinium, and vilanterol was associated with a lower rate of exacerbations in chronic obstructive pulmonary disease.

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

A childhood measles infection may increase the risk for post-bronchodilator airflow obstruction in middle-age adults via its interaction with asthma and smoking.

Cardiovascular Complications of COPD

Cardiovascular Complications of COPD

A 55-year-old man with chronic obstructive pulmonary disease reports having some mild chest pain.

Early Asthma Symptoms Linked to Lung Function in Adolescents Born Preterm

Early Asthma Symptoms Linked to Lung Function in Adolescents Born Preterm

Preterm-born children had significantly more frequent preschool wheeze compared with children born at term.

No significant benefit of long-acting muscarinic antagonists over long-acting beta-agonists in reducing exacerbation risk in uncontrolled, persistent asthma

Adjunct long-acting muscarinic antagonist (LAMA) use with corticosteroids was associated with reduced exacerbation risk compared with placebo in patients with uncontrolled, persistent asthma. However, LAMA, long-acting beta-agonist (LABA), and inhaled corticosteroids (triple therapy) were not associated with lower risk for exacerbations compared with LABA and inhaled corticosteroids alone.

Perioperative Risk Assessment in a Patient With COPD

Perioperative Risk Assessment in a Patient With COPD

A 64-year-old man with chronic obstructive pulmonary disease, diabetes, chronic kidney disease, and morbid obesity seeks preoperative approval for femoral popliteal bypass surgery.

Fixed-Dosed Dual Bronchodilators for COPD: Overview and Clinician Interview

Fixed-Dosed Dual Bronchodilators for COPD: Overview and Clinician Interview

Treating chronic obstructive pulmonary disease remains challenging, particularly in terms of choosing the appropriate fixed-dose combination bronchodilator.

COPD Risk Predicted by Large Airway Dimensions on Computed Tomography

COPD Risk Predicted by Large Airway Dimensions on Computed Tomography

Greater Pi10 was associated with incident spirometry-defined chronic obstructive pulmonary disease in a general population-based sample without clinical lung disease.

Lung Function in Cystic Fibrosis Affected by Sputum Viscoelasticity and Poor Clearance

Lung Function in Cystic Fibrosis Affected by Sputum Viscoelasticity and Poor Clearance

Sputum viscoelastic properties were associated with lung function and disease status in patients with cystic fibrosis.

Asthma Exacerbation Risk Lower With SMART Therapy

Asthma Exacerbation Risk Lower With SMART Therapy

In patients with persistent asthma, single maintenance and reliever therapy was associated with a lower risk for exacerbations compared with inhaled corticosteroids as controller therapy and short-acting beta-agonists as relief therapy.

Tai Chi Helps Improve Respiratory Function in COPD

Tai Chi Helps Improve Respiratory Function in COPD

Tai chi found to be as effective as pulmonary rehabilitation for patients with chronic obstructive pulmonary disease.

Debating Noninvasive vs Invasive Ventilation in Acute Exacerbations of COPD

Debating Noninvasive vs Invasive Ventilation in Acute Exacerbations of COPD

It is still not known whether differences in mortality rates between patients who receive noninvasive vs invasive ventilation for acute exacerbations of COPD can be attributed to less severe disease or other factors.

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

Regardless of blood eosinophil count, omalizumab was an effective treatment in adult and pediatric patients with severe allergic asthma.

Distinct Lung Function Trajectories Associated With COPD Risk

Distinct Lung Function Trajectories Associated With COPD Risk

Researchers identified 6 distinct FEV1 lung function trajectories, 3 of which were responsible for 75% of the COPD burden.

Novel Cystic Fibrosis Treatment Granted Fast Track Status

Novel Cystic Fibrosis Treatment Granted Fast Track Status

Proteostasis Therapeutics is developing the combination treatment which includes a novel transmembrane conductance regulator (CFTR) amplifier (PTI-428), a third generation corrector (PTI-801) and a potentiator (PTI-808).

Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

Findings for subsequent allergic disease following infant exposure in the first six months of life.

Lonhala Magnair Now Available for Long-Term COPD Maintenance

Lonhala Magnair Now Available for Long-Term COPD Maintenance

Lonhala Magnair is available as a 25mcg strength inhalation solution per 1mL vial.

Simple Lung Function Tests in Primary Care Help ID Early COPD

Simple Lung Function Tests in Primary Care Help ID Early COPD

Peak flow meter, microspirometry are optimal, with full spirometry for positive results.

Sleep Quality in COPD May Predict Overall Quality of Life

Sleep Quality in COPD May Predict Overall Quality of Life

Sleep quality in patients with chronic obstructive pulmonary disease may be a significant predictor of multiple metrics of quality of life.

Two Inhalers Go Head-to-Head in COPD Exacerbation Study

Two Inhalers Go Head-to-Head in COPD Exacerbation Study

Study authors concluded, "Combining tiotropium and olodaterol did not reduce exacerbation rate as much as expected compared with tiotropium alone."

COPD: Disease Management Care vs Recommended Care Alone

COPD: Disease Management Care vs Recommended Care Alone

Disease management added to recommended care in chronic obstructive pulmonary disease was not superior to recommended care alone.

Efficacy of Different Doses of Glycopyrronium Via a Metered Dose Inhaler in COPD

Efficacy of Different Doses of Glycopyrronium Via a Metered Dose Inhaler in COPD

Four different doses of glycopyrronium delivered via metered dose inhaler were compared for safety and efficacy in the treatment of chronic obstructive pulmonary disease.

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Patients with asthma or chronic obstructive pulmonary disease have especially high rates of nonadherence, even in comparison with other chronic diseases.

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

In children with allergic asthma, SCIT may reduce long-term asthma medication use.

Smartinhaler Sensor for Symbicort Will Be Available Over-the-Counter

Smartinhaler Sensor for Symbicort Will Be Available Over-the-Counter

The Smartinhaler sensor is a device installed onto a patient's inhaler to monitor and promote asthma and COPD medication adherence.

Asthma Exacerbation Risk Reduced With Inhaled Corticosteroids Plus LABAs or LAMAs

Asthma Exacerbation Risk Reduced With Inhaled Corticosteroids Plus LABAs or LAMAs

Long-acting muscarinic antagonists or long-acting β-agonists plus inhaled corticosteroids lowered the risk for asthma exacerbations vs adjuvant placebo.

Asthma Development in Early Childhood May Hinge on Early Life Stress

Asthma Development in Early Childhood May Hinge on Early Life Stress

Prenatal and early life stress, including societal stress, have been implicated in the development of asthma and other allergic diseases in children.

Increased inhaled glucocorticoids do not prevent asthma exacerbations in children: The STICS trial

In children aged 5 to 11 years with mild to moderate persistent asthma who were treated with daily inhaled glucocorticoids, quintupling the dose during the initial signs of worsening asthma control did not reduce the rate of severe exacerbations.

Specific COPD Questionnaire Cutoff Threshold May Identify More Symptomatic Patients

Specific COPD Questionnaire Cutoff Threshold May Identify More Symptomatic Patients

The Clinical COPD Questionnaire cutoff point of 1.4 demonstrated a better agreement with other COPD measures in patients with more symptomatic disease.

Emphysema Threshold on CT Imaging May Have Predictive Value for COPD

Emphysema Threshold on CT Imaging May Have Predictive Value for COPD

Patients with chronic obstructive pulmonary disease with 5% emphysema based on thoracic computed tomography (CT) imaging may be at a greater risk for poor outcomes.

Effect of Tobacco Smoke Exposure in Children With or Without Asthma

Effect of Tobacco Smoke Exposure in Children With or Without Asthma

Current tobacco smoke exposure is not associated with airflow obstruction in school-aged children, but prenatal smoking is associated with airflow obstruction in children with asthma.

Severe Asthmatic Cough May Be Improved With Bronchial Thermoplasty

Severe Asthmatic Cough May Be Improved With Bronchial Thermoplasty

Bronchial thermoplasty can treat severe asthmatic cough that is unresponsive to conventional therapies.

Cystic Fibrosis-Related Pathogen Risk With Chronic Azithromycin Use

Cystic Fibrosis-Related Pathogen Risk With Chronic Azithromycin Use

Patients with cystic fibrosis who took azithromycin had a significantly lower risk for detection of new nontuberculous mycobacteria, methicillin-resistant Staphylococcus aureus, and Burkholderia cepacia complex.

COPD Combination Therapy May Improve Lung Hyperinflation

COPD Combination Therapy May Improve Lung Hyperinflation

Combination treatment with indacaterol-glycopyrronium may improve cardiac function in patients with chronic obstructive pulmonary disease.

Glucocorticoids Do Not Increase Fracture Risk in COPD

Glucocorticoids Do Not Increase Fracture Risk in COPD

Intermittent use of high-dose glucocorticoids did not increase the risk for fracture in patients with COPD.

Lung Cancer Risk May Be Predicted by Frequency of COPD Exacerbations

Lung Cancer Risk May Be Predicted by Frequency of COPD Exacerbations

Independent predictive factors of lung cancer in chronic obstructive pulmonary disease may include frequency of exacerbations, in addition to airflow obstruction and visual emphysema.

Asthma Symptoms, Risks, and Comorbidities According to Smoking Status

Asthma Symptoms, Risks, and Comorbidities According to Smoking Status

Smokers and nonsmokers had similar symptoms and risk factors present for asthma, but differed in comorbidities.

COPD, Respiratory Symptoms Associated With "Western" Diet

COPD, Respiratory Symptoms Associated With "Western" Diet

Researchers used data from the Atherosclerosis Risk in Communities Study to assess associations between dietary pattern and pulmonary assessments.

Severe COPD Exacerbations, Hospitalizations Reduced With Azithromycin

Severe COPD Exacerbations, Hospitalizations Reduced With Azithromycin

Long-term continuous cyclic azithromycin therapy for severe chronic obstructive pulmonary disease was associated with reductions in exacerbations and hospitalizations.

Effect of Allergen Exposure Reduction Efforts on Asthma Outcomes

Effect of Allergen Exposure Reduction Efforts on Asthma Outcomes

According to a systematic literature review, there was inconclusive evidence that single indoor allergen interventions were effective at improving asthma outcomes.

Asthma Medications May Negatively Affect Fertility in Women

Asthma Medications May Negatively Affect Fertility in Women

Short-acting beta-agonists for asthma management may reduce fertility rates in women with asthma.

Meeting Patients' Expectations for Asthma, Allergy Testing Improves Satisfaction

Meeting Patients' Expectations for Asthma, Allergy Testing Improves Satisfaction

When patients visiting an allergy/immunology outpatient clinic had expectations met regarding diagnosis and testing, they were more likely to be satisfied with their visit.

Asthma in Primary Care: Spirometry Underused in Diagnosis

Asthma in Primary Care: Spirometry Underused in Diagnosis

Spirometry may be underused for the diagnosis and monitoring of asthma in the primary care setting.

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