Pulmonary Vascular Disorders

Clinical Challenge: 40-Year-Old Woman With Worsening Dyspnea on Exertion

Clinical Challenge: 40-Year-Old Woman With Worsening Dyspnea on Exertion

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A 40-year-old woman presents with worsening shortness of breath after being treated with long-acting nifedipine for 2 years.

Pulmonary Arterial Hypertension: Using Biomarkers to Assess Treatment Response

Pulmonary Arterial Hypertension: Using Biomarkers to Assess Treatment Response

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Using biomarkers in pulmonary arterial hypertension may be a less invasive strategy for assessing response to treatment.

Thoracic and Pulmonary Conditions Associated With Connective Tissue Disease

Thoracic and Pulmonary Conditions Associated With Connective Tissue Disease

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Pulmonary and thoracic symptoms often coincide with initial presentation of connective tissue disease.

Idiopathic PAH vs Scleroderma-Associated PAH: Pulmonary Function and Hemodynamic Differences

Idiopathic PAH vs Scleroderma-Associated PAH: Pulmonary Function and Hemodynamic Differences

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Results show statistically significant differences between SSc-PAH groups and iPAH groups for variables including age, sex, FVC capacity, total lung capacity, and FEV1, among others.

Impaired Cerebral Pressure-Flow Relationship in PAH

Impaired Cerebral Pressure-Flow Relationship in PAH

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Patients with pulmonary arterial hypertension have reduced cerebrovascular reactivity to CO2.

Pulmonary Arterial Hypertension: Mechanisms of Exercise Intolerance

Pulmonary Arterial Hypertension: Mechanisms of Exercise Intolerance

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Respiratory muscle dysfunction, iron deficiency, and skeletal muscle dysfunction have been implicated as mechanisms for exercise intolerance in pulmonary arterial hypertension.

Extent of Right Ventricular Epicardial Vascularization in Pulmonary Arterial Hypertension

Extent of Right Ventricular Epicardial Vascularization in Pulmonary Arterial Hypertension

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Right ventricular epicardial vasculature is more extensive in patients with pulmonary arterial hypertension compared with individuals without disease.

Association Between Pulmonary Hypertension and Hereditary Hemorrhagic Telangiectasia

Association Between Pulmonary Hypertension and Hereditary Hemorrhagic Telangiectasia

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A study sought to describe the occurrence of different types of pulmonary hypertension in hereditary hemorrhagic telangiectasia.

Examining Anxiety, Depression Rates in CTEPH, PAH

Examining Anxiety, Depression Rates in CTEPH, PAH

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Depression, anxiety, and reduced healthcare-related quality of life are common in patients with either pulmonary arterial hypertension or chronic thromboembolic pulmonary hypertension.

Clinical Case: Patient With COPD and Worsening Dyspnea on Exertion

Clinical Case: Patient With COPD and Worsening Dyspnea on Exertion

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A 65-year-old man with COPD presents with worsening exertional dyspnea.

Pulmonary Veno-Occlusive Disease Affects Survival in PAH/Systemic Sclerosis

Pulmonary Veno-Occlusive Disease Affects Survival in PAH/Systemic Sclerosis

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Having at least 2 features of pulmonary veno-occlusive disease demonstrated a trend toward worse survival in patients with pulmonary arterial hypertension and systemic sclerosis.

Guidelines Needed for 6-Minute Walk Test in Idiopathic Pulmonary Fibrosis

Guidelines Needed for 6-Minute Walk Test in Idiopathic Pulmonary Fibrosis

Specific guidelines should be developed for the use of the 6-minute walk test in idiopathic pulmonary fibrosis.

Pulmonary Arterial Hypertension: Future Treatment May Depend on Race and Ethnicity

Pulmonary Arterial Hypertension: Future Treatment May Depend on Race and Ethnicity

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Pulmonary arterial hypertension tends to vary in presentation in patients of different races and ethnicities.

Right Ventricular Morphology Predictive of Pulmonary Hypertension Type

Right Ventricular Morphology Predictive of Pulmonary Hypertension Type

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Differences in right ventricular morphology may predict the hemodynamic nature of pulmonary hypertension.

Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension

Pulmonary Endarterectomy in Chronic Thromboembolic Pulmonary Hypertension

Pulmonary endarterectomy is an effective and durable treatment for chronic thromboembolic pulmonary hypertension.

Managing Pulmonary Hypertension in Preterm Neonates: Updates in an Emerging Field

Managing Pulmonary Hypertension in Preterm Neonates: Updates in an Emerging Field

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Prenatal factors such as intrauterine growth retardation, infection, and placental inflammation can affect lung development in neonates.

Anatomic Location of Thrombus Not Affected Outcomes of Surgical Pulmonary Embolectomy

Anatomic Location of Thrombus Not Affected Outcomes of Surgical Pulmonary Embolectomy

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Patients with either central or peripheral pulmonary embolism had positive outcomes with surgical pulmonary embolectomy for peripheral distribution of thrombus.

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