Composite Echo Score Predicts PH in Interstitial Lung Disease

Composite Echo Score Predicts PH in Interstitial Lung Disease

The variables for the stepwise echocardiographic score included right ventricular systolic pressure, early pulmonary regurgitation gradient, right atrial area size, tricuspid regurgitation velocity, left ventricle eccentricity index, and right ventricle fractional area change.

60-Day Mortality Not Significantly Lower With ECMO in ARDS

60-Day Mortality Not Significantly Lower With ECMO in ARDS

In patients with very severe acute respiratory distress syndrome, 60-day mortality was not significantly lower with venovenous extracorporeal membrane oxygenation than with conventional treatment.

Initiative Cuts Overuse of Tests, Treatments for Bronchiolitis

Initiative Cuts Overuse of Tests, Treatments for Bronchiolitis

The initiative helped reduce the ordering of chest radiographs, respiratory viral testing, and bronchodilators.

Migraine a Common Comorbidity in Individuals With Sarcoidosis

Migraine a Common Comorbidity in Individuals With Sarcoidosis

The frequency of migraine and sarcoidosis comorbidity was examined in a cohort study.

Expert Consensus on Chronic Hypersensitivity Pneumonitis Diagnostic Criteria

Expert Consensus on Chronic Hypersensitivity Pneumonitis Diagnostic Criteria

Experts in interstitial lung disease identified 18 items of importance for diagnosing chronic hypersensitivity pneumonitis.

Idiopathic Pulmonary Fibrosis Outcomes Improved by Gastroesophageal Reflux Treatment

Idiopathic Pulmonary Fibrosis Outcomes Improved by Gastroesophageal Reflux Treatment

Treatment for gastroesophageal reflux significantly reduced mortality in idiopathic pulmonary fibrosis and improved transplant-free survival.

Predictors Identified for Myositis-Related Interstitial Lung Disease Mortality

Predictors Identified for Myositis-Related Interstitial Lung Disease Mortality

Researchers identified independent predictors of short-term dermatomyositis- or polymyositis-related interstitial lung disease mortality.

Treatment for Idiopathic Pulmonary Fibrosis Gets Orphan Drug Designation

Treatment for Idiopathic Pulmonary Fibrosis Gets Orphan Drug Designation

RP5063 is a new chemical entity with a novel mechanism of multimodal modulation of serotonin and dopamine signaling pathways.

Mortality in Mechanically Ventilated Community-Acquired Pneumonia With or Without ARDS

Mortality in Mechanically Ventilated Community-Acquired Pneumonia With or Without ARDS

The risk for death in patients with community-acquired pneumonia who were given mechanical ventilation does not seem to be affected by the presence of acute respiratory distress syndrome.

High-Flow vs Standard Oxygen Therapy in Infants With Bronchiolitis

High-Flow vs Standard Oxygen Therapy in Infants With Bronchiolitis

High-flow oxygen therapy may be more effective in preventing care escalation in infants with bronchiolitis compared with standard oxygen therapy.

Idiopathic Pulmonary Fibrosis in Dentists May Be Linked to Occupational Exposure

Idiopathic Pulmonary Fibrosis in Dentists May Be Linked to Occupational Exposure

Several patients were treated for idiopathic pulmonary fibrosis were identified as dental personnel.

Nebulized Hypertonic Saline vs Normal Saline in Infants With Acute Bronchiolitis

Nebulized Hypertonic Saline vs Normal Saline in Infants With Acute Bronchiolitis

Nebulized hypertonic saline may decrease length of hospital stay and improve clinical severity scores in infants with acute bronchiolitis.

Thyroid hormone supplementation may be a promising treatment for idiopathic pulmonary fibrosis [PreClinical]

An enzyme involved in thyroid hormone activation was found to be elevated in patients with pulmonary fibrosis.

Improving Prognosis in Idiopathic Pulmonary Fibrosis-Associated Pulmonary Hypertension

Improving Prognosis in Idiopathic Pulmonary Fibrosis-Associated Pulmonary Hypertension

Bosentan may benefit a subset of patients with idiopathic pulmonary fibrosis-associated pulmonary hypertension.

A 67-Year-Old Woman With Hypertension, Diabetes Presents With Shortness of Breath

A 67-Year-Old Woman With Hypertension, Diabetes Presents With Shortness of Breath

After being treated for pyelonephritis and discharged to a nursing facility, a 67-year-old woman presents to the emergency department with shortness of breath.

Comparing Treatments for Acute Respiratory Distress Syndrome

Comparing Treatments for Acute Respiratory Distress Syndrome

In patients with acute respiratory distress syndrome, cisatracurium does not improve mortality when compared with vecuronium, but is associated with improvements in other outcomes.

Chronic Lung Disease Research in the Pipeline: An Interview With Augustine M.K. Choi, MD

Chronic Lung Disease Research in the Pipeline: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD, Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

Examining the Efficacy of Carbon Monoxide Therapy in Idiopathic Pulmonary Fibrosis: An Interview With Augustine M.K. Choi, MD

Examining the Efficacy of Carbon Monoxide Therapy in Idiopathic Pulmonary Fibrosis: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD, Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

Identifying New Therapeutics for Pulmonary Diseases: An Interview With Augustine M.K. Choi, MD

Identifying New Therapeutics for Pulmonary Diseases: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD of Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

Overview of Autophagy Research in COPD: An Interview With Augustine M.K. Choi, MD

Overview of Autophagy Research in COPD: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD, Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

Bronchiolitis Treatment in Infants Varies by Hospital

Bronchiolitis Treatment in Infants Varies by Hospital

The use of evidence-based supportive therapies varies by hospital site for infants with bronchiolitis,

Smoking Affects Lung Microbiota, ARDS Risk in Trauma Patients

Smoking Affects Lung Microbiota, ARDS Risk in Trauma Patients

A significant enrichment of potential pathogens occurred in patients who smoked and who were admitted to the hospital for severe trauma.

Ventilator-Induced Lung Injury in Acute Respiratory Distress Syndrome

Ventilator-Induced Lung Injury in Acute Respiratory Distress Syndrome

Translational research has increased the understanding of the mechanisms of ventilator-induced lung injury.

Lung Recruitment Maneuver With Titrated PEEP Increases Mortality in Moderate to Severe ARDS

Lung Recruitment Maneuver With Titrated PEEP Increases Mortality in Moderate to Severe ARDS

A randomized trial sought to determine whether the use of titrated positive end-expiratory pressure influenced the 28-day mortality risk in patients with acute respiratory distress syndrome.

Bronchoalveolar Lavage for Diagnosis of Idiopathic Pulmonary Fibrosis: Point/Counterpoint

Bronchoalveolar Lavage for Diagnosis of Idiopathic Pulmonary Fibrosis: Point/Counterpoint

Lung disease experts Athol Wells, MD, and Joshua Mooney, MD, MS, debate the diagnostic value of bronchoalveolar lavage in idiopathic pulmonary fibrosis.

Acute Respiratory Distress Syndrome and Refractory Hypoxemia: Selecting Evidence-Based Treatments

Acute Respiratory Distress Syndrome and Refractory Hypoxemia: Selecting Evidence-Based Treatments

Treatments for acute respiratory distress syndrome that have less evidence to support their use have been overused by clinicians.

Distinct Clinical Phenotypes in Interstitial Lung Disease May Better Predict Outcomes

Distinct Clinical Phenotypes in Interstitial Lung Disease May Better Predict Outcomes

Clustering patients with interstitial lung disease independently predicted progression-free and transplant-free survival.

Chronic Respiratory Disease Mortality Rates Increase From 1980 to 2014

Chronic Respiratory Disease Mortality Rates Increase From 1980 to 2014

Mortality rates and changes in mortality rates for chronic respiratory diseases in the United States varied by county, sex, and particular disease type.

Depression and Anxiety Affect QoL in Idiopathic Pulmonary Fibrosis

Depression and Anxiety Affect QoL in Idiopathic Pulmonary Fibrosis

Depression and anxiety may affect quality of life for patients with idiopathic pulmonary fibrosis.

Low Tidal Volume Strategy in Acute Respiratory Distress Syndrome

Low Tidal Volume Strategy in Acute Respiratory Distress Syndrome

A low tidal volume ventilation strategy in patients with acute respiratory distress syndrome demonstrated a trend toward improved mortality.

Effect of Conservative Fluid Management on Mortality in ARDS Patients

Effect of Conservative Fluid Management on Mortality in ARDS Patients

Researchers examined the efficacy of conservative vs liberal fluid management in ARDS on disease mortality.

Pulmonary Sarcoidosis: Independent Predictors of Mortality

Pulmonary Sarcoidosis: Independent Predictors of Mortality

Most patients with sarcoidosis have a good prognosis, but age, extensive fibrosis, and pulmonary hypertension are associated with an increase in mortality.

Azithromycin Improves Survival in Idiopathic Pulmonary Fibrosis

Azithromycin Improves Survival in Idiopathic Pulmonary Fibrosis

Azithromycin may be an effective treatment option for acute exacerbation of idiopathic pulmonary fibrosis.

Mechanical Ventilation Increases Costs and Mortality in IPF

Mechanical Ventilation Increases Costs and Mortality in IPF

Mechanical ventilation does not improve outcomes in IPF patients, lengthens hospital stays, and increases costs.

Examining Pulmonary Function Measures in Pediatric SLE

Examining Pulmonary Function Measures in Pediatric SLE

Fractional exhaled nitric oxide levels directly correlated to subclinical pulmonary disease activity in children with systemic lupus erythematosus.

Does ICU Volume Impact Mortality and Length of Stay in ARDS?

Does ICU Volume Impact Mortality and Length of Stay in ARDS?

More than 300,000 individual ICU stays were examined to determine the benefit of ICU volume related to ARDS outcomes.

Joblessness High Following Respiratory Distress Syndrome

Joblessness High Following Respiratory Distress Syndrome

One year after hospital discharge, high rates of acute respiratory distress survivors are jobless.

Case Study: A Patient Presents With Recurring Influenza Symptoms

Right-sided abdominal pain, vomitting, fever, and mild diarrhea were all present in a 66-year-old woman with a history of sarcoidosis and hypertension.

Chest Radiographic Screening in Active Uveitis to Diagnose Sarcoidosis

Chest Radiographic Screening in Active Uveitis to Diagnose Sarcoidosis

Abnormal chest radiographs were noted in patients with active uveitis of unknown origin.

Diagnostic Performance of Idiopathic Pulmonary Fibrosis Algorithm

Diagnostic Performance of Idiopathic Pulmonary Fibrosis Algorithm

The idiopathic pulmonary fibrosis algorithm has a sensitivity of 55.6% and positive predictive value of 42.2%.

Predicting Reduced 6-Minute Walk Distance in Sarcoidosis-Associated PH

Predicting Reduced 6-Minute Walk Distance in Sarcoidosis-Associated PH

Data from 150 patients suggested that lung diffusion capacity is the most relevant predictive factor for reduced 6-minute walk distance in SAPH.

Predicting Survival in IPF With CT-Measured Pulmonary Artery: Aorta Ratio

Predicting Survival in IPF With CT-Measured Pulmonary Artery: Aorta Ratio

Computed tomography-derived pulmonary artery-to-aorta ratio can predict pulmonary artery pressure and survival in patients with idiopathic pulmonary fibrosis.

Restrictive Spirometry Pattern Predictive of Arterial Stiffness

Restrictive Spirometry Pattern Predictive of Arterial Stiffness

Researchers examined nearly 3000 men and women to determine the relationship between restrictive spirometry pattern, reduced FVC, and arterial stiffness.

Predicting Survival Trajectories in IPF Using 2 T-Cell Biomarkers

Predicting Survival Trajectories in IPF Using 2 T-Cell Biomarkers

Researchers found a significant association with declining forced vital capacity and diffusing capacity of the lung for carbon monoxide with ICOS and CD28.

Increased Mortality Related to Interstitial Lung Abnormalities

Increased Mortality Related to Interstitial Lung Abnormalities

Researchers examined data from 4 cohort studies to assess the risk of all-cause mortality associated with interstitial lung abnormalities.

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