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Early Oseltamivir Use Linked to Clinical Benefits in Influenza Complicating ARDS

Early Oseltamivir Use Linked to Clinical Benefits in Influenza Complicating ARDS

Patients with acute respiratory distress syndrome and confirmed influenza diagnosis treated ≤6 hours with oseltamivir had reduced length of hospital stay and a lower rate of mortality.

Trends in Sarcoidosis-Related Hospitalizations in the United States

Trends in Sarcoidosis-Related Hospitalizations in the United States

Blacks experience a significantly higher rate of sarcoidosis-associated hospitalizations compared with whites.

COPD, ILD Do Not Benefit More From Bilateral Transplantation Only Listing

COPD, ILD Do Not Benefit More From Bilateral Transplantation Only Listing

No meaningful associations were detected in procedural listing preferences and survival outcomes in patients with COPD or interstitial lung disease awaiting lung transplant.

Ambulatory Oxygen Improves Interstitial Lung Disease Quality of Life

Ambulatory Oxygen Improves Interstitial Lung Disease Quality of Life

Health-related quality of life and isolated exertional hypoxia in patients with interstitial lung disease may be improved by the use of ambulatory oxygen.

Ofev Shown to Slow Idiopathic Pulmonary Fibrosis Progression Long-Term

Ofev Shown to Slow Idiopathic Pulmonary Fibrosis Progression Long-Term

The primary objective was to characterize the long-term safety and tolerability of Ofev in patients with IPF; efficacy endpoints included annual rate of decline in forced vital capacity (FVC) calculated over 192 weeks.

No Benefit From Nintedanib Plus Sildenafil in Idiopathic Pulmonary Fibrosis

No Benefit From Nintedanib Plus Sildenafil in Idiopathic Pulmonary Fibrosis

Nintedanib plus sildenafil did not improve St. George's Respiratory Questionnaire scores in patients with idiopathic pulmonary fibrosis.

Factors Predictive of Escalated Care in Infant Bronchiolitis

Factors Predictive of Escalated Care in Infant Bronchiolitis

Factors predictive of escalated care in infant bronchiolitis include oxygen saturation <90%, nasal flaring/grunting, apnea, retractions, and age 2 months or younger.

Idiopathic Pulmonary Fibrosis and GERD: An Unclear Connection

Idiopathic Pulmonary Fibrosis and GERD: An Unclear Connection

Although gastroesophageal reflux disease and idiopathic pulmonary fibrosis may be related, the association between the 2 disorders is most likely confounded by smoking.

FDA Fast-Tracks Pamrevlumab for Idiopathic Pulmonary Fibrosis

FDA Fast-Tracks Pamrevlumab for Idiopathic Pulmonary Fibrosis

The FDA's designation was based on data from a Phase 2 placebo-controlled trial that demonstrated pamrevlumab could potentially address an unmet medical need for this condition.

Laparoscopic Antireflux Surgery for Treating Idiopathic Pulmonary Fibrosis

Laparoscopic Antireflux Surgery for Treating Idiopathic Pulmonary Fibrosis

Laparoscopic antireflux surgery was safe and well tolerated in patients with idiopathic pulmonary fibrosis and abnormal acid gastroesophageal reflux.

Interstitial Lung Disease Diagnosis Improved Using Rheumatologic Assessment

Interstitial Lung Disease Diagnosis Improved Using Rheumatologic Assessment

Adding routine rheumatologic assessments to interstitial lung disease diagnosis could reduce the need for invasive procedures and improve diagnostic accuracy.

ARDS Exacerbated by Low to Moderate Air Pollution in Severe Trauma

ARDS Exacerbated by Low to Moderate Air Pollution in Severe Trauma

Exposure to ozone, nitrogen dioxide, sulfur dioxide, carbon monoxide, and particulate matter <2.5 μm demonstrated strong associations with acute respiratory distress syndrome.

Rituximab Safe and Efficacious Alternative Treatment for Scleroderma

Rituximab Safe and Efficacious Alternative Treatment for Scleroderma

Rituximab is a safe and effective alternative to cyclophosphamide in managing the progression of scleroderma and subsequent development of interstitial lung disease.

Treatment for Bronchiolitis Obliterans Gains Orphan Drug Status

Treatment for Bronchiolitis Obliterans Gains Orphan Drug Status

Bronchiolitis obliterans is the leading cause of morbidity and mortality in the pulmonary transplant population with ≥50% of patients who receive a lung transplant developing the condition within 5 years.

Anti-Fibrotic Drug Gets Orphan Drug Status for Idiopathic Pulmonary Fibrosis

Anti-Fibrotic Drug Gets Orphan Drug Status for Idiopathic Pulmonary Fibrosis

Targeting TGF-β signaling in a tissue-specific manner allows the drug to modulate the fibrotic cascade with maximum clinical effects while avoiding adverse events.

Chronic Cough in Interstitial Lung Disease: More Clinical Trials Needed

Chronic Cough in Interstitial Lung Disease: More Clinical Trials Needed

An expert panel developed suggestions for chronic cough management in interstitial lung disease, but more clinical trials are needed to establish recommendations.

FDA: Cancer Relapse Linked to Azithromycin Use to Prevent Serious Lung Condition

FDA: Cancer Relapse Linked to Azithromycin Use to Prevent Serious Lung Condition

Pfizer has terminated the ALLOZITHRO trial (N=480) due to this increased risk.

Nintedanib and Pirfenidone Tolerated in Idiopathic Pulmonary Fibrosis

Nintedanib and Pirfenidone Tolerated in Idiopathic Pulmonary Fibrosis

Many patients with idiopathic pulmonary fibrosis in an international phase 4 study tolerated combination therapy with pirfenidone and nintedanib.

Lung Transplant Survival Lower During Acute Exacerbations of IPF

Lung Transplant Survival Lower During Acute Exacerbations of IPF

Compared with individuals who had stable idiopathic pulmonary fibrosis, those with an acute exacerbation had a significantly shorter survival, especially at the 3 year follow-up.

Low Nailfold Capillary Density Associated With Lung Involvement in Juvenile Dermatomyositis

Low Nailfold Capillary Density Associated With Lung Involvement in Juvenile Dermatomyositis

Low nailfold capillary density is associated with impaired pulmonary function tests and more frequent high-resolution computed tomography abnormalities in patients with juvenile dermatomyositis.

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