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ZOVIRAX TABLETS
Viral infections

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Drug Name:

ZOVIRAX TABLETS Rx

Generic Name and Formulations:
Acyclovir 400mg, 800mg.

Company:
Mylan Inc.

Therapeutic Use:

Infectious Diseases Resource Center »

Indications for ZOVIRAX TABLETS:

Genital herpes. Herpes zoster. Varicella.

Adult:

May give with food. Genital herpes: Initially 200mg every 4hrs (5 times daily) for 10 days. Chronic: 400mg 2 times daily or 200mg 3–5 times daily for up to 12 months, then reevaluate. Intermittent: (at 1^st sign of recurrence) 200mg every 4hrs (5 times daily) for 5 days. Herpes zoster: 800mg every 4hrs (5 times daily) for 7–10 days. Varicella (start at earliest sign/symptom): 800mg 4 times daily for 5 days. Renal impairment: reduce dose (see full labeling); give another dose after hemodialysis.

Children:

<2yrs: not recommended. ≥2yrs: Varicella (start at earliest sign/symptom): 20mg/kg 4 times daily for 5 days; max 800mg/dose. >40kg: as adult. Others: see full labeling.

Contraindications:

Valacyclovir hypersensitivity.

Warnings/Precautions:

Renal impairment: see full labeling. Maintain adequate hydration. Pregnancy (Cat.B). Nursing mothers.

Interactions:

Avoid nephrotoxic drugs. Potentiated by probenecid.

Pharmacological Class:

Nucleoside analogue.

Adverse Reactions:

Nausea, vomiting, headache, CNS disturbances (esp. elderly), diarrhea, vertigo, myalgia, rash, malaise, viral resistance, renal failure, thrombotic thrombocytopenic purpura/hemolytic uremic syndrome in immunocompromised patients.

How Supplied:

Caps, tabs—100; Susp—473mL