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Investigational Cream Promising for Atopic Dermatitis

Investigational Cream Promising for Atopic Dermatitis

In a phase 2b trial, success rates were higher with TRPV1 antagonist than with vehicle cream.

Nearly 11% of US Adults Have Food Allergy

Nearly 11% of US Adults Have Food Allergy

Nearly 20% of US adults think they are food-allergic; shellfish, milk, peanut are the most common allergies.

First-in-Class OTC Bioelectronic Device for Sinus Pain Gets FDA-Cleared

First-in-Class OTC Bioelectronic Device for Sinus Pain Gets FDA-Cleared

Tivic Health Systems announced that ClearUP Sinus Pain Relief has been cleared by the Food and Drug Administration (FDA) for the treatment of sinus pain due to allergic rhinitis, or hay fever, in adults aged ≥18 years.

Exposure to Heat in Car May Decrease Epinephrine Concentration in Autoinjectors

Exposure to Heat in Car May Decrease Epinephrine Concentration in Autoinjectors

In order to determine the effect of heat exposure on the concentration of adrenaline in EAIs, the study authors placed nine 0.3mg EpiPen Senior EAIs inside a parked car from 8:30 AM until 8:30 PM on a summer day.

Dapsone Efficacy Examined in Patients With Chronic Spontaneous Urticaria

Dapsone Efficacy Examined in Patients With Chronic Spontaneous Urticaria

In order to assess the safety and efficacy of dapsone, a sulfone antibiotic, in the treatment of CSU, the study authors reviewed the medical records of 79 CSU patients treated with dapsone.

Common Ragweed Projected to Expand in Northeastern United States

Common Ragweed Projected to Expand in Northeastern United States

Based on global climate models, ragweed distribution may expand in the northeastern United States.

Eczema Mean Cumulative Lifetime Prevalence Is 9.9%

Eczema Mean Cumulative Lifetime Prevalence Is 9.9%

The highest rates of active disease were seen for children aged 0 to 17 years and older adults aged 75 to 99 years.

Limited Doses of FDA-Approved Epinephrine Generic Now Available

Limited Doses of FDA-Approved Epinephrine Generic Now Available

The generic version of the EpiPen Jr (epinephrine injection, USP) 0.15mg as well as additional supply of the generic version of the EpiPen Auto-Injector 0.3mg will be made available in 2019.

Lanadelumab Reduces Attack Rate in Hereditary Angioedema

Lanadelumab Reduces Attack Rate in Hereditary Angioedema

Significant reduction in attack rate compared with placebo seen for 3 dose regimens of lanadelumab.

Telling Time by Asthma, Allergy Symptom Severity

Telling Time by Asthma, Allergy Symptom Severity

Clinicians are gaining a better understanding of how asthma and allergies are regulated by the circadian clock, which will help patients better alleviate their symptoms.

Childhood Asthma, Wheezing Linked to Maternal Blood Pressure in Pregnancy

Childhood Asthma, Wheezing Linked to Maternal Blood Pressure in Pregnancy

Consistent associations were observed per 5 mm Hg higher maternal blood pressures in early pregnancy with lower FEV1/FVC.

Food Allergy Prevalence Is 7.6% in US Children

Food Allergy Prevalence Is 7.6% in US Children

The most prevalent allergens are peanut, milk, shellfish, and tree nut.

Epinephrine Personal Autoinjectors Cost-Effective at $24

Epinephrine Personal Autoinjectors Cost-Effective at $24

The epinephrine autoinjector incremental cost-effectiveness ratio was $2,742,697 per quality-adjusted life-year at a market cost of $715 per twin pack.

Almost 2% of Children Have Milk Allergy

Almost 2% of Children Have Milk Allergy

Of the children with food allergy, 53% of infants have milk allergy vs 15% of teenagers.

AR101 May Protect Against Accidental Peanut Exposure

AR101 May Protect Against Accidental Peanut Exposure

More than 67% of patients who received AR101 were able to ingest a dose of 600 mg or more of peanut protein at the exit food challenge, without dose-limiting symptoms

Increased Medication Burden for Patients With Both Asthma and Allergies

Increased Medication Burden for Patients With Both Asthma and Allergies

Patients with both asthma and allergies had a significant increase in the number of prescriptions dispensed for controller medications.

Olopatadine/Mometasone Nasal Spray Reduces Seasonal Allergy Symptoms

Olopatadine/Mometasone Nasal Spray Reduces Seasonal Allergy Symptoms

Patients who received olopatadine/mometasone either once or twice daily experienced significant improvements in their instantaneous Total Nasal Symptom Scores compared with placebo.

Short Interruption of House Dust Mite Immunotherapy Well Tolerated

Short Interruption of House Dust Mite Immunotherapy Well Tolerated

Treatment reinitiation after a short interruption was well tolerated in patients taking standardized quality house mite sublingual immunotherapy tablets.

Eosinophilic Esophagitis Symptoms Reduced With Anti-Interleukin 13 Antibody

Eosinophilic Esophagitis Symptoms Reduced With Anti-Interleukin 13 Antibody

Significantly greater reductions in the mean esophageal eosinophil counts occurred in patients who received the humanized anti-interleukin 13 antibody, RPC4046.

Increased Risk of Depression, Suicide in Atopic Dermatitis

Increased Risk of Depression, Suicide in Atopic Dermatitis

The prevalence of depression in patients with atopic dermatitis was higher than in those without atopic dermatitis.

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