Allergies

Increased Medication Burden for Patients With Both Asthma and Allergies

Increased Medication Burden for Patients With Both Asthma and Allergies

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Patients with both asthma and allergies had a significant increase in the number of prescriptions dispensed for controller medications.

Olopatadine/Mometasone Nasal Spray Reduces Seasonal Allergy Symptoms

Olopatadine/Mometasone Nasal Spray Reduces Seasonal Allergy Symptoms

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Patients who received olopatadine/mometasone either once or twice daily experienced significant improvements in their instantaneous Total Nasal Symptom Scores compared with placebo.

Short Interruption of House Dust Mite Immunotherapy Well Tolerated

Short Interruption of House Dust Mite Immunotherapy Well Tolerated

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Treatment reinitiation after a short interruption was well tolerated in patients taking standardized quality house mite sublingual immunotherapy tablets.

Eosinophilic Esophagitis Symptoms Reduced With Anti-Interleukin 13 Antibody

Eosinophilic Esophagitis Symptoms Reduced With Anti-Interleukin 13 Antibody

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Significantly greater reductions in the mean esophageal eosinophil counts occurred in patients who received the humanized anti-interleukin 13 antibody, RPC4046.

Increased Risk of Depression, Suicide in Atopic Dermatitis

Increased Risk of Depression, Suicide in Atopic Dermatitis

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The prevalence of depression in patients with atopic dermatitis was higher than in those without atopic dermatitis.

Upadacitinib Improves Pruritus in Moderate to Severe Atopic Dermatitis

Upadacitinib Improves Pruritus in Moderate to Severe Atopic Dermatitis

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Upadacitinib, a selective janus kinase-1 inhibitor, was associated with early improvements in pruritus in patients with moderate to severe atopic dermatitis.

Olopatadine/Mometasone Nasal Spray Effective for Perennial Allergic Rhinitis

Olopatadine/Mometasone Nasal Spray Effective for Perennial Allergic Rhinitis

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GSP301 treatment was associated with a significant improvement in reflective and instantaneous Total Nasal Symptom Scores compared with placebo.

GSP301 Nasal Spray Improves QoL Seasonal Allergic Rhinitis

GSP301 Nasal Spray Improves QoL Seasonal Allergic Rhinitis

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Patients who received a fixed-dose combination nasal spray showed significantly improved Physician-assessed Nasal Symptom Scores compared with those who received placebo.

Lanadelumab Well-Tolerated in Hereditary Angioedema

Lanadelumab Well-Tolerated in Hereditary Angioedema

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Patients with hereditary angioedema who received lanadelumab exhibited few cases of hypersensitivity and had low immunogenicity.

Grass Pollen Tablet AEs Spontaneously Resolve in Pediatric Allergic Rhinitis

Grass Pollen Tablet AEs Spontaneously Resolve in Pediatric Allergic Rhinitis

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Adverse drug reactions from the 300IR 5-grass pollen tablet occurred in approximately half of patients but typically resolved within a week of treatment.

Grass Pollen Tablet Approved for Younger Patients With Grass Pollen Allergy

Grass Pollen Tablet Approved for Younger Patients With Grass Pollen Allergy

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The FDA has approved the use of Oralair for the treatment of grass pollen-induced allergic rhinitis in pediatric patients aged 5-9.

Cetirizine Provides More Benefits for Acute Urticaria Than Diphenhydramine

Cetirizine Provides More Benefits for Acute Urticaria Than Diphenhydramine

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The change from baseline in 2-hour pruritus score was shown to be statistically noninferior from IV cetirizine to IV diphenhydramine, in favor of IV cetirizine.

Does Prearrival Epinephrine Adversely Affect Pediatric Anaphylaxis Patients?

Does Prearrival Epinephrine Adversely Affect Pediatric Anaphylaxis Patients?

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Despite many pediatric patients receiving higher than recommended doses of epinephrine for their weight, they did not present with epinephrine-related symptoms.

Several Asthma, Allergy Groups Express "Deep Concern" Over Primatene MIST Approval

Several Asthma, Allergy Groups Express "Deep Concern" Over Primatene MIST Approval

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Several asthma and allergy groups expressed "deep concern" over the recent FDA approval of Primatene MIST.

Atopic Dermatitis Prevalence 7.3% in US Adults

Atopic Dermatitis Prevalence 7.3% in US Adults

Patients with atopic dermatitis and more severe disease have higher scores on dermatology life quality index.

FDA: Lifted Label Defect May Delay Emergency Treatment With Epinephrine

FDA: Lifted Label Defect May Delay Emergency Treatment With Epinephrine

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The FDA has issued a safety communication alerting patients and healthcare providers that for some EpiPen and EpiPen Jr auto-injectors, and their authorized generics, the device label may become stuck to the inside of the carrier tube and potentially delay administration.

Expiration Dates Extended for Certain Lots of Generic Epinephrine Injection

Expiration Dates Extended for Certain Lots of Generic Epinephrine Injection

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The expiration dates for certain lots of epinephrine injection, USP auto-injector 0.15mg and 0.3mg have been extended by 2 month.

Wheezing Exacerbations Predicted by Allergen Sensitization and Exposure

Wheezing Exacerbations Predicted by Allergen Sensitization and Exposure

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Class 1 was defined as minimal sensitization, class 2 was defined as sensitization with indoor pet exposure, class 3 was defined as sensitization with tobacco smoke exposure, and class 4 was defined as multiple sensitization and eczema.

Rhinitis Nearly Ubiquitous in Urban Adolescents With Asthma

Rhinitis Nearly Ubiquitous in Urban Adolescents With Asthma

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The majority of study participants had rhinitis at baseline, including perennial allergic rhinitis with seasonal exacerbations, which is the most severe phenotype.

Childhood Non-Atopic Rhinitis Increases Adult Asthma Risk

Childhood Non-Atopic Rhinitis Increases Adult Asthma Risk

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Childhood non-atopic rhinitis is associated with an increased risk for adult asthma.

Dupilumab Studies Show Benefit in Chronic Rhinosinusitis With Nasal Polyps

Dupilumab Studies Show Benefit in Chronic Rhinosinusitis With Nasal Polyps

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In both studies, at 24 weeks, patients treated with dupilumab plus corticosteroid nasal spray experienced a 51% and 57% improvement in nasal congestion/obstruction severity vs 15% and 19% improvement with nasal spray alone.

Reduced Perinatal Proteobacteria Exposure Linked to Childhood Wheezing

Reduced Perinatal Proteobacteria Exposure Linked to Childhood Wheezing

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Lower exposure to Proteobacteria in umbilical cord serum was associated with an increased risk for childhood wheezing.

Delabeling Patients as Beta-Lactam Allergic Requires Record Updates

Delabeling Patients as Beta-Lactam Allergic Requires Record Updates

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Changes in allergy records were suggested by the allergy service consult for 62% of the patients.

Additional Symjepi Dosage Strength Approved for Anaphylaxis Treatment

Additional Symjepi Dosage Strength Approved for Anaphylaxis Treatment

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Both doses will be supplied in single-dose, prefilled syringes for manual injection.

Pest Allergies in Urban Adolescents Exacerbate Poorly Controlled Asthma

Pest Allergies in Urban Adolescents Exacerbate Poorly Controlled Asthma

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Cockroach and mouse allergies were most often associated with poorly controlled asthma and exacerbations in urban adolescents.

Allergy, But Not Asthma, Risk Increased in Children of East Asian Descent

Allergy, But Not Asthma, Risk Increased in Children of East Asian Descent

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Children of East Asian-born parents had an increased risk for allergic rhinitis and aeroallergen sensitization compared with children of Caucasian ancestry.

PUFAs Inversely Associated With Asthma in Preschool Children

PUFAs Inversely Associated With Asthma in Preschool Children

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Total omega-3 and omega-6 plasma polyunsaturated fatty acids relative abundances were significantly inversely correlated with asthma/recurrent wheeze and allergic sensitization.

Relationship Between Atopic Disorders May Be Age Dependent

Relationship Between Atopic Disorders May Be Age Dependent

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Although allergic sensitization and hay fever rates increased as children grew older, the rates of asthma dropped.

Addition of High-Dose Guaifenesin Benefits Patient With Chronic Respiratory Conditions

Addition of High-Dose Guaifenesin Benefits Patient With Chronic Respiratory Conditions

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According to the report, the patient complained of a non-productive cough, accumulation of mucus, and post-nasal drip and requested a thorough assessment of her medical conditions.

Asthma Control Not Improved With School-Supervised Inhaled Corticosteroid Use

Asthma Control Not Improved With School-Supervised Inhaled Corticosteroid Use

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In a population of primarily Latino children from low-income households, a program of school-supervised use of once-daily inhaled corticosteroids failed to improve asthma control.

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