In May, the Food and Drug Administration posted a drug shortage alert, adding Mylan's EpiPen (epinephrine injection) to the drug shortage list.
Unlike other generic approvals, epinephrine auto-injectors are considered "combination products" because they consist of both a drug and a device, making the approval process more challenging.
The FDA designation was supported by data from 7 studies evaluating the safety and efficacy of Xolair against various food allergens (eg, peanut, milk, egg, others).
The recalled nasal decongestant has a Lot number of 173089J and an expiration date of 09/19; it is packaged in 0.5 fluid ounce bottles.
The Company is currently conducting a Phase 3 trial (APeX-2) and a long-term safety study (APeX-S) evaluating 2 doses of the treatment.
Patients with aspirin-exacerbated respiratory disease had significantly lower levels of depression symptoms and higher quality of life compared with patients with asthma only.
Physicians can help children and teens adhere to eczema treatment plants by simplifying treatment, creating reminders, and sharing success stories.
Oral administration of BCX7353 at dose of 125 mg resulted in lower rate of hereditary angioedema attacks vs placebo.
Grass, other weeds, and unclassified pollen were significantly associated with increased risk for asthma hospitalization in young children.
Sensitization to Aspergillus fumigatus increased the risk for severe asthma.
An increase in atheroma burden and plaques with less stable features demonstrated an association with immunoglobulin E to α-Gal.
Cytokines produced by mitogen-stimulated immune cells from pregnant women without asthma were shown to be associated with the development of asthma in their children.
Respiratory symptoms were more common in older children compared with infants who presented with food-induced anaphylaxis.
In addition to respiratory sensitivity to aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs), patients with AERD oftentimes experience an additional allergic reaction when drinking alcohol.
Clinically meaningful benefits were seen in patients with chronic rhinosinusitis, but the treatment effect was imprecise.
Lone star tick is most common in the South, but may be spreading to new areas.
The eFlow® nebulizer delivered CDP7766 without evidence of degradation, loss of potency, aggregation, or formation of particulates in a model of asthma in cynomolgus macaques.
Many patients with moderate to severe atopic dermatitis have inadequate disease control.
Bronchiectasis-associated genera included Aspergillus, Cryptococcus, Clavispora, Botrytis, and Alternaria.
Children with the early-onset persistent bronchial hyperresponsiveness phenotype had the highest blood eosinophil count and total serum IgE levels as well as sensitization rates.
The approval was based on data from a randomized, single-blind, multicenter, dose-ranging, crossover study which evaluated the safety and efficacy of Cinryze in 12 pediatric patients (7 to 11 years old).
The mean rate of exacerbations declined significantly after 1 year of subcutaneous immunotherapy in children with moderate to severe allergic asthma exacerbations.
Allergic rhinitis also had a negative effect on daily functioning, sleep, school productivity, and academic performance.
Most adults (52%) reported that an EAI was not used during their most severe reaction, even though it would have been beneficial, 45% said they didn't have it with them at the time.
Because determining an appropriate treatment plan for a patient depends on the subtype of the disease, it is imperative for providers to know and understand the underlying mechanisms of CRS as well as the components included in a medical evaluation of a patient.
A nasal immune-response pattern characterized by lower non-interferon antiviral immune response mediators and higher type 2 and type 17 cytokines was significantly associated with recurrent wheeze at 1 year.
The pharmacokinetics trial, which included 60 participants with seasonal allergies, also demonstrated rapid drug absorption with the intranasal spray.
Adenoidectomy and tonsillectomy in children by age 9 were associated with higher long-term risks for respiratory, infectious, and allergic diseases.
Vitamin D supplementation appears to reduce the recurrent wheezing by 12 months of age in black infants born prematurely.
Fluticasone Propionate Nasal Spray is a corticosteroid indicated for the management of the nasal symptoms of perennial nonallergic rhinitis in adults and pediatric patients aged 4 years and older.