Generic Name and Formulations:
Orlistat 60mg; caps.
Indications for ALLI:
Adjunct to reduced-calorie, low-fat diet for weight loss in overweight adults.
≥18yrs: 1 cap with each fat-containing meal. Max: 180mg/day. Also, take a multivitamin once daily at bedtime.
<18yrs: not recommended.
Organ transplant. Chronic malabsorption syndrome. Cholestasis.
Gallbladder disorder. Pancreatitis. Kidney stones. Seizures. Pregnancy, nursing mothers: not recommended.
Concomitant cyclosporine: not recommended. May decrease absorption of fat-soluble vitamins; supplement diet with a multivitamin (separate dosing by at least 2 hours). Variable effects when concomitant anticoagulants (eg, warfarin), amiodarone, antidiabetics, antiepileptics, antiretrovirals, thyroid drugs, or other weight loss products; monitor and dose adjustments may be needed.
GI effects (oily spotting, flatus with discharge, fecal urgency, fatty/oily stools, oily evacuation, increased defecation, fecal incontinence); rare: hepatic injury.
Caps—60, 90, 120, 170