Asthma Archives

Pest Allergies in Urban Adolescents Exacerbate Poorly Controlled Asthma

Pest Allergies in Urban Adolescents Exacerbate Poorly Controlled Asthma

Cockroach and mouse allergies were most often associated with poorly controlled asthma and exacerbations in urban adolescents.

Allergy, But Not Asthma, Risk Increased in Children of East Asian Descent

Allergy, But Not Asthma, Risk Increased in Children of East Asian Descent

Children of East Asian-born parents had an increased risk for allergic rhinitis and aeroallergen sensitization compared with children of Caucasian ancestry.

PUFAs Inversely Associated With Asthma in Preschool Children

PUFAs Inversely Associated With Asthma in Preschool Children

Total omega-3 and omega-6 plasma polyunsaturated fatty acids relative abundances were significantly inversely correlated with asthma/recurrent wheeze and allergic sensitization.

Relationship Between Atopic Disorders May Be Age Dependent

Relationship Between Atopic Disorders May Be Age Dependent

Although allergic sensitization and hay fever rates increased as children grew older, the rates of asthma dropped.

Benralizumab Efficacy Maintained in Long-Term Severe Eosinophilic Asthma Study

Benralizumab Efficacy Maintained in Long-Term Severe Eosinophilic Asthma Study

Results from the extension trial showed a similar safety and tolerability profile for Fasenra as that seen in SIROCCO and CALIMA.

Ambient Particulate Matter Linked to Emergency Asthma Care

Ambient Particulate Matter Linked to Emergency Asthma Care

An increase was seen in asthma hospital visits with increasing ambient particulate matter in San Luis Valley.

Budesonide/Formoterol for the Prevention of Serious Asthma Exacerbations

Budesonide/Formoterol for the Prevention of Serious Asthma Exacerbations

The SYGMA trials assessed the use of an as-needed combined corticosteroid/beta-agonist inhaler in patients with mild asthma.

Anti-IL5 Treatments Compared in Patients With Severe Eosinophilic Asthma

Anti-IL5 Treatments Compared in Patients With Severe Eosinophilic Asthma

Currently, 3 anti-interleukin (IL)5 pathway-directed treatments (benralizumab, mepolizumab, reslizumab) have been approved by the Food and Drug Administration for the treatment of severe asthma with an eosinophilic phenotype.

Asthma Control Not Improved With School-Supervised Inhaled Corticosteroid Use

Asthma Control Not Improved With School-Supervised Inhaled Corticosteroid Use

In a population of primarily Latino children from low-income households, a program of school-supervised use of once-daily inhaled corticosteroids failed to improve asthma control.

Childhood Asthma Risk Assessed Using Respiratory Phenotypes

Childhood Asthma Risk Assessed Using Respiratory Phenotypes

Overall, 5 phenotypes were identified and differentiated mainly by patterns of wheezing and aeroallergen sensitization: low wheeze-low atopy, low wheeze-high atopy, transient wheeze-low atopy, high wheeze-low atopy, and high wheeze-high atopy.

IL-24 Shows Correlation Between Lower, Upper Airways in Allergic Asthma

IL-24 Shows Correlation Between Lower, Upper Airways in Allergic Asthma

Nasal expression of interleukin-10 showed an association with perceived stress burden, while perceived stress burden was strongly associated with asthma control score.

Tezepelumab Gets Breakthrough Therapy Designation for Severe Asthma

Tezepelumab Gets Breakthrough Therapy Designation for Severe Asthma

The designation was based on data from the Phase 2b PATHWAY trial that evaluated 3 doses of tezepelumab as add-on therapy in patients with a history of asthma exacerbations and uncontrolled asthma receiving inhaled corticosteroids/long-acting β-agonist with or without oral corticosteroids and additional asthma controllers vs placebo.

Asthma Affected Differently by Subcutaneous and Visceral Abdominal Fat

Asthma Affected Differently by Subcutaneous and Visceral Abdominal Fat

Significant negative correlations were seen between visceral fat area and bronchial lumen diameter and lumen area, and significant positive correlations were seen between subcutaneous fat area and bronchial wall area and total area.

Prevalence of Asthma Exacerbations That Also Meet Anaphylaxis Criteria

Prevalence of Asthma Exacerbations That Also Meet Anaphylaxis Criteria

A total of 8% of patients with asthma exacerbations met the criteria for diagnosing anaphylaxis, with 3.4% having likely experienced anaphylaxis.

Low Ozone Levels Negatively Affect Subsets of Adolescents With Asthma

Low Ozone Levels Negatively Affect Subsets of Adolescents With Asthma

African-American adolescents with asthma who took appropriate therapies had both decreased lung function and elevated blood lipid levels when exposed to short-term low ozone levels.

Asthma Medicine Recalled Due to Tablet Mix-Up That May Pose Safety Risk

Asthma Medicine Recalled Due to Tablet Mix-Up That May Pose Safety Risk

The risk of a mixing-up the treatments is especially high for pregnant women, says the Food and Drug Administration (FDA), as losartan is indicated to treat high blood pressure and could harm or kill a fetus.

Asthma, COPD Readmissions Independently Predicted by Chronic Rhinitis

Asthma, COPD Readmissions Independently Predicted by Chronic Rhinitis

Comorbid chronic rhinitis is significantly associated with 30-day hospital readmissions related to asthma and chronic obstructive pulmonary disease.

Asthma and ADHD: What's the Link?

Asthma and ADHD: What's the Link?

There is a significant relationship between attention deficit hyperactivity disorder and asthma.

Many Children With Asthma Do Not Have Medications Ready

Many Children With Asthma Do Not Have Medications Ready

Low-income urban preschoolers with asthma may not meet home medication readiness criteria.

Small Airway Function in Children With Mild to Moderate Asthma

Small Airway Function in Children With Mild to Moderate Asthma

In children who were symptomatic, small conducting airways ventilation inhomogeneity and alveolar nitric oxide concentration were both significantly associated with asthma exacerbations.

Asthma and Allergic Rhinitis May Be Risk Factors for Migraine in Adolescents

Asthma and Allergic Rhinitis May Be Risk Factors for Migraine in Adolescents

Adolescents who have asthma or allergic rhinitis may be at higher risk for developing migraine.

Does Early Life Vitamin D Status Affect Asthma, Wheeze in Later Life?

Does Early Life Vitamin D Status Affect Asthma, Wheeze in Later Life?

Pooled estimates from cohort studies suggested there was no association between antenatal blood vitamin D levels or vitamin D intake and asthma in offspring.

Telemedicine Interventions Can Improve Asthma Control, Quality of Life

Telemedicine Interventions Can Improve Asthma Control, Quality of Life

Combined tele-case management and tele-consultation was the most effective form of telemedicine for improving asthma control.

Labetalol Use Higher in Patients With Asthma and Preeclampsia

Labetalol Use Higher in Patients With Asthma and Preeclampsia

Use of labetalol vs other antihypertensives is linked to increased risk of status asthmaticus.

High Blood Eosinophil Count Linked to Asthma-Related Hospital Readmission

High Blood Eosinophil Count Linked to Asthma-Related Hospital Readmission

A high blood eosinophil count may increase the risk for a second asthma-related hospitalization within 1 year following an initial hospitalization.

Hailie Solution Now Available for Tracking Asthma, COPD Medication Use

Hailie Solution Now Available for Tracking Asthma, COPD Medication Use

Through Bluetooth technology, clinicians and patients will be able to share and monitor inhaler usage.

Biologic Therapy Selection for Severe Asthma: Factors to Consider

Biologic Therapy Selection for Severe Asthma: Factors to Consider

The authors write that once severe asthma is diagnosed, clinicians should determine asthma endotype (Type2-high or Type2-low) to help choose the best therapy for the patient.

Dupilumab reduces systemic glucocorticoid use in severe asthmatics

Patients with severe asthma who are glucocorticoid dependent and treated with dupilumab for 24 weeks used significantly lower doses of glucocorticoids while maintaining asthmatic control compared with patients treated with placebo.

Basophil Levels in Childhood Asthma May Indicate Risk for Future Exacerbations

Basophil Levels in Childhood Asthma May Indicate Risk for Future Exacerbations

Children with asthma and/or wheeze who have a basophil level above 0.18% of the circulating peripheral blood mononuclear cell population have a higher risk for future exacerbations.

COPD and Asthma Overlap: Individual vs Environmental Risk Factors in Women

COPD and Asthma Overlap: Individual vs Environmental Risk Factors in Women

Socioeconomic and lifestyle risk factors had a more significant role in the development of COPD and asthma overlap syndrome in women than air pollution.

Comorbid Asthma Not Associated With Need for Surgery in Crohn Disease

Comorbid Asthma Not Associated With Need for Surgery in Crohn Disease

Asthma was not associated with a risk for intestinal resection surgery in patients with Crohn disease.

Electronic Asthma Action Plans Help Reduce Exacerbations

Electronic Asthma Action Plans Help Reduce Exacerbations

Electronic asthma action plans supported by text messaging services may improve control and reduce exacerbations.

Quality of Life in Aspirin-Exacerbated Respiratory Disease vs Asthma Only

Quality of Life in Aspirin-Exacerbated Respiratory Disease vs Asthma Only

Patients with aspirin-exacerbated respiratory disease had significantly lower levels of depression symptoms and higher quality of life compared with patients with asthma only.

Asthma and Poorly Controlled Asthma May Increase Atrial Fibrillation Risk

Asthma and Poorly Controlled Asthma May Increase Atrial Fibrillation Risk

Individuals with clinician-diagnosed asthma were at an estimated 38% higher risk for atrial fibrillation.

Hailie Sensor Gets FDA Clearance for Additional Asthma Inhalers

Hailie Sensor Gets FDA Clearance for Additional Asthma Inhalers

The Hailie sensor attaches to the asthma or chronic obstructive pulmonary disease (COPD) inhaler to monitor and help patient adherence.

Asthma Hospitalization Risk in Children From Grass, Weed, and Other Pollens

Asthma Hospitalization Risk in Children From Grass, Weed, and Other Pollens

Grass, other weeds, and unclassified pollen were significantly associated with increased risk for asthma hospitalization in young children.

Illicit Drug Use in Asthma: Heroin, Cocaine, and Marijuana Worsen Symptoms

Illicit Drug Use in Asthma: Heroin, Cocaine, and Marijuana Worsen Symptoms

Inhaling and smoking heroin and cocaine increase the risk for asthma exacerbations and decreased pulmonary function; marijuana is associated with wheezing, cough, and sputum production.

Severe Asthma Risk Increased From Aspergillus fumigatus Sensitization

Severe Asthma Risk Increased From Aspergillus fumigatus Sensitization

Sensitization to Aspergillus fumigatus increased the risk for severe asthma.

Fewer Asthma Exacerbations With LABA Plus Inhaled Glucocorticoid

Fewer Asthma Exacerbations With LABA Plus Inhaled Glucocorticoid

Combination therapy with a long-acting β2-agonist plus an inhaled glucocorticoid for asthma was not associated with a significantly higher risk for serious asthma-related events compared with an inhaled glucocorticoid alone.

Childhood Respiratory Risk Factor Profiles Predict Lung Function, COPD

Childhood Respiratory Risk Factor Profiles Predict Lung Function, COPD

Frequent asthma, bronchitis, allergy demonstrated the strongest association with , lower FEV1, lower FEV1/forced vital capacity, and increased risk for COPD.

Cytokine Profiles of Pregnant Women Predict Asthma in Children

Cytokine Profiles of Pregnant Women Predict Asthma in Children

Cytokines produced by mitogen-stimulated immune cells from pregnant women without asthma were shown to be associated with the development of asthma in their children.

CDC: Wildfire Smoke Poses Health Risks

CDC: Wildfire Smoke Poses Health Risks

The US Centers for Disease Control offers steps to minimize exposure to wildfire smoke, particularly for those with chronic conditions.

Free Vitamin D3 Inferior to Total Concentrations in Predicting Asthma Response

Free Vitamin D3 Inferior to Total Concentrations in Predicting Asthma Response

No associations were found between free concentration vitamin D3 levels and treatment failure or exacerbation rates in adults with asthma

Inhaled IL-13 Monoclonal Antibody Inhibits IL-13 in Animal Asthma Model

Inhaled IL-13 Monoclonal Antibody Inhibits IL-13 in Animal Asthma Model

The eFlow® nebulizer delivered CDP7766 without evidence of degradation, loss of potency, aggregation, or formation of particulates in a model of asthma in cynomolgus macaques.

Anti-IL-5 Therapy Eligibility Characteristics Examined in Adult-Onset Asthma

Anti-IL-5 Therapy Eligibility Characteristics Examined in Adult-Onset Asthma

Patients with severe asthma were more often current smokers at diagnosis and had higher body mass index at follow-up compared with patients with nonsevere asthma and anti-IL-5 therapy-eligible asthma.

Patient Engagement in Asthma Treatment Plans May Improve Quality of Life

Patient Engagement in Asthma Treatment Plans May Improve Quality of Life

Older adults with asthma and a greater desire for involvement in decision making have higher asthma-related quality of life.

Obstructive Sleep Apnea in Asthma: Gaining Control by Losing Weight

Obstructive Sleep Apnea in Asthma: Gaining Control by Losing Weight

Poor control of asthma and obstructive sleep apnea can feed off one another, according to Michelle Zeidler, MD, pulmonologist at the University of California, Los Angeles, and director of the UCLA Sleep Fellowship Program.

Asthma Risk Increased With Early-Onset Persistent Bronchial Hyperresponsiveness

Asthma Risk Increased With Early-Onset Persistent Bronchial Hyperresponsiveness

Children with the early-onset persistent bronchial hyperresponsiveness phenotype had the highest blood eosinophil count and total serum IgE levels as well as sensitization rates.

Subcutaneous Immunotherapy Shows Promise for Allergic Asthma Exacerbations

Subcutaneous Immunotherapy Shows Promise for Allergic Asthma Exacerbations

The mean rate of exacerbations declined significantly after 1 year of subcutaneous immunotherapy in children with moderate to severe allergic asthma exacerbations.

Asthma Exacerbation, Treatment Failure Prevention During Step-Down Therapy

Asthma Exacerbation, Treatment Failure Prevention During Step-Down Therapy

A hospital emergency department visit in the prior year was associated with subsequent asthma treatment failure.

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory Viruses Linked to Treatment Failure in Asthma Exacerbations

Respiratory pathogens were associated with an increased risk for treatment failure in children with asthma exacerbations.

Tralokinumab Ineffective for Eosinophilic Airway Inflammation in Asthma

Tralokinumab Ineffective for Eosinophilic Airway Inflammation in Asthma

Tralokinumab did not have a significant effect on eosinophilic airway inflammation in moderate to severe asthma that was inadequately controlled on inhaled corticosteroids.

Viruses not linked to asthma exacerbation severity

Identified viral pathogens were not associated with asthma exacerbation severity, but were linked to increased treatment failure.

Immune-Response Cluster in Infant Respiratory Syncytial Virus Linked With Recurrent Wheeze

Immune-Response Cluster in Infant Respiratory Syncytial Virus Linked With Recurrent Wheeze

A nasal immune-response pattern characterized by lower non-interferon antiviral immune response mediators and higher type 2 and type 17 cytokines was significantly associated with recurrent wheeze at 1 year.

Budesonide-formoterol as needed superior to terbutaline in mild asthma: The SYGMA trial

In patients with mild asthma, use of the inhaled combined corticosteroid and beta agonist budesonide-formoterol as needed was superior to terbutaline as needed with respect to electronically recorded weeks of well-controlled asthma.

Various Perinatal Risks Associated With Maternal Asthma Diagnosis

Various Perinatal Risks Associated With Maternal Asthma Diagnosis

Women with a diagnosis of asthma may have a higher risk for preterm birth, and their infants may have an increased risk for perinatal mortality, low birth weight, fetal growth restriction, and asphyxia.

Omalizumab Inhibits Respiratory Reactions During Aspirin Desensitization

Omalizumab Inhibits Respiratory Reactions During Aspirin Desensitization

In patients with aspirin exacerbated respiratory disease, treatment with omalizumab resulted in "clinically silent" aspirin desensitization.

Asthma Exacerbation Risk With As-Needed Budesonide-Formoterol vs Maintenance Budesonide

Asthma Exacerbation Risk With As-Needed Budesonide-Formoterol vs Maintenance Budesonide

Budesonide-formoterol as needed was not inferior compared with budesonide maintenance therapy in terms of severe asthma exacerbation rates, but may be inferior for controlling symptoms.

Greater Use of Tobacco Products Among Youth With Asthma

Greater Use of Tobacco Products Among Youth With Asthma

E-cigarettes are the most commonly used product in middle and high school students with or without asthma.

Effectiveness of Budesonide-Formoterol vs Terbutaline in Asthma Symptom Control

Effectiveness of Budesonide-Formoterol vs Terbutaline in Asthma Symptom Control

There was a 60% lower rate of severe asthma exacerbations in individuals treated with budesonide-formoterol compared with individuals treated with terbutaline as needed.

Asthma-Associated Chemicals in Hair Products for Black Women Raise Concerns

Asthma-Associated Chemicals in Hair Products for Black Women Raise Concerns

Chemicals linked with endocrine disruption and asthma identified in hair products used by black women and children.

Budesonide Improved Epithelial Barrier Function in Asthma

Budesonide Improved Epithelial Barrier Function in Asthma

Researchers evaluated barrier dysfunction by exposing viral models to budesonide, montelukast, formoterol, or a combination.

Inhaled Interferon-Beta 1a Does Not Reduce Severe Asthma Exacerbations

Inhaled Interferon-Beta 1a Does Not Reduce Severe Asthma Exacerbations

Inhaled interferon-beta 1 a did not significantly reduce acute asthma exacerbations during respiratory viral infections.

Longer Hospital Stay, Higher Costs With Unwarranted Antibiotics in Asthma Exacerbations

Longer Hospital Stay, Higher Costs With Unwarranted Antibiotics in Asthma Exacerbations

Longer stay and higher costs were associated with antibiotic administration in adults hospitalized for an asthma exacerbation without documented evidence of a lung infection.

Morning vs Evening ICS Dosing in Asthma: Efficacies Compared

Morning vs Evening ICS Dosing in Asthma: Efficacies Compared

Inhaled corticosteroids for asthma dosed once daily in the evening appeared to offer some benefit in trough FEV1 and morning peak expiratory flow.

Anxiety, Depression Associated With Poor Self-Perceived Asthma Control

Anxiety, Depression Associated With Poor Self-Perceived Asthma Control

Investigators conducted a prospective survey to examine the association between asthma symptom severity and symptoms of depression and anxiety.

Overweight, Obesity Linked to Asthma Development in Children and Adolescents

Overweight, Obesity Linked to Asthma Development in Children and Adolescents

Overweight or obese children are more likely to develop new onset asthma compared with normal weight controls.

Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma

Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma

Researchers examined the association of timing, frequency, and class of antibiotic use during pregnancy on the development of childhood asthma.

Sertraline Not Beneficial for Symptomatic Chronic Breathlessness

Sertraline Not Beneficial for Symptomatic Chronic Breathlessness

Sertraline does not prove to be beneficial for relief of chronic breathlessness.

Efficacy, Safety of Dupilumab in Corticosteroid-Dependent Severe Asthma

Efficacy, Safety of Dupilumab in Corticosteroid-Dependent Severe Asthma

Subcutaneous dupilumab significantly reduced the use of oral corticosteroids in patients with corticosteroid-dependent severe asthma.

Lung Function in Severe Asthma Improved With Benralizumab

Lung Function in Severe Asthma Improved With Benralizumab

Peak expiratory flow increases were greater with benralizumab than placebo in patients with severe eosinophilic asthma.

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Oral contraceptive use in women of reproductive age may increase the risk for lifetime asthma.

Vitamin D Supplementation Improves Asthma Control

Vitamin D Supplementation Improves Asthma Control

In individuals with asthma and vitamin D deficiency, vitamin D supplementation improved asthma control.

Macrolides for Asthma Management: An Updated Review

Macrolides for Asthma Management: An Updated Review

While macrolides had no direct effect on lung function, their use significantly improved asthma control and quality of life in patients with asthma.

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

The study authors examined data obtained from the 2007-2008 National Survey of Children's Health (NSCH) to determine the prevalence, risk factors, as well as the severity of asthma phenotypes.

Most Concerning Med Issues Explored Among Youth With Asthma

Most Concerning Med Issues Explored Among Youth With Asthma

The study authors reported, "The most commonly reported problems by youth were: (a) hard to remember when to take the asthma medication (54%) and (b) hard to use asthma medication at school (34%)."

Feasibility of At-Home Use Injectable Tx for Severe Asthma Assessed

Feasibility of At-Home Use Injectable Tx for Severe Asthma Assessed

Of the total 573 APFS dispensed, 1 malfunctioned and 1 was considered nonfunctional because it was not returned. The study authors also reported that patient-use error only led to 2 unsuccessful at-home administrations.

ICS Therapy May Not Be Enough for Asthma Patients With Elevated Eosinophils

ICS Therapy May Not Be Enough for Asthma Patients With Elevated Eosinophils

The study aimed to determine the association between ICS therapy adherence and the occurrence of asthma exacerbations in patients with high blood eosinophil levels.

Type 2 Biomarkers May Predict Exacerbations in Severe Refractory Asthma

Type 2 Biomarkers May Predict Exacerbations in Severe Refractory Asthma

The positive association between type 2 biomarkers and severe exacerbations in severe refractory asthma may not extend to mild to moderate asthma.

Low Neighborhood Walkability Increases Risk of Asthma in Kids

Low Neighborhood Walkability Increases Risk of Asthma in Kids

Children living in neighborhoods with low walkability are at increased risk of asthma.

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

Pediatric Asthma Outcomes With Physician Cultural Communication Training

Pediatric Asthma Outcomes With Physician Cultural Communication Training

Physician asthma care education Plus training resulted in improvements in provider confidence, perceived skill in communicating cross culturally, and short-term asthma-specific outcomes.

Asthma Care Program Improves Provider Documentation, Clinical Measures

Asthma Care Program Improves Provider Documentation, Clinical Measures

An asthma care program improved implementation of guidelines as well as provider documentation in 65 community centers in 4 states that serve patients with asthma.

Current Smokers With Severe Asthma Distinguished by Sputum Proteomics

Current Smokers With Severe Asthma Distinguished by Sputum Proteomics

Patients with severe asthma who were current smokers were distinguishable from ex-smokers based on their sputum proteomic level of colony stimulating factor 2.

Children With Status Asthmaticus Do Not Benefit From Magnesium Sulfate

Children With Status Asthmaticus Do Not Benefit From Magnesium Sulfate

Children with status asthmaticus who received magnesium sulfate therapy were on continuous albuterol for a longer duration.

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD overlap linked to higher prevalence of sleep-related symptoms, including difficulty falling asleep and maintaining sleep, early-morning awakening, and excessive daytime sleepiness.

Early Child Care Attendance and Asthma, Wheeze Risk: What's the Link?

Early Child Care Attendance and Asthma, Wheeze Risk: What's the Link?

Early child care attendance increased the risk for wheeze in children ≤2 years of age but decreased the risk for asthma in children 3 to 5 years of age.

Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

A childhood measles infection may increase the risk for post-bronchodilator airflow obstruction in middle-age adults via its interaction with asthma and smoking.

Early Asthma Symptoms Linked to Lung Function in Adolescents Born Preterm

Early Asthma Symptoms Linked to Lung Function in Adolescents Born Preterm

Preterm-born children had significantly more frequent preschool wheeze compared with children born at term.

No significant benefit of long-acting muscarinic antagonists over long-acting beta-agonists in reducing exacerbation risk in uncontrolled, persistent asthma

Adjunct long-acting muscarinic antagonist (LAMA) use with corticosteroids was associated with reduced exacerbation risk compared with placebo in patients with uncontrolled, persistent asthma. However, LAMA, long-acting beta-agonist (LABA), and inhaled corticosteroids (triple therapy) were not associated with lower risk for exacerbations compared with LABA and inhaled corticosteroids alone.

Asthma Exacerbation Risk Lower With SMART Therapy

Asthma Exacerbation Risk Lower With SMART Therapy

In patients with persistent asthma, single maintenance and reliever therapy was associated with a lower risk for exacerbations compared with inhaled corticosteroids as controller therapy and short-acting beta-agonists as relief therapy.

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

Regardless of blood eosinophil count, omalizumab was an effective treatment in adult and pediatric patients with severe allergic asthma.

Distinct Lung Function Trajectories Associated With COPD Risk

Distinct Lung Function Trajectories Associated With COPD Risk

Researchers identified 6 distinct FEV1 lung function trajectories, 3 of which were responsible for 75% of the COPD burden.

Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

Findings for subsequent allergic disease following infant exposure in the first six months of life.

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Patients with asthma or chronic obstructive pulmonary disease have especially high rates of nonadherence, even in comparison with other chronic diseases.

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

In children with allergic asthma, SCIT may reduce long-term asthma medication use.

Smartinhaler Sensor for Symbicort Will Be Available Over-the-Counter

Smartinhaler Sensor for Symbicort Will Be Available Over-the-Counter

The Smartinhaler sensor is a device installed onto a patient's inhaler to monitor and promote asthma and COPD medication adherence.

Asthma Exacerbation Risk Reduced With Inhaled Corticosteroids Plus LABAs or LAMAs

Asthma Exacerbation Risk Reduced With Inhaled Corticosteroids Plus LABAs or LAMAs

Long-acting muscarinic antagonists or long-acting β-agonists plus inhaled corticosteroids lowered the risk for asthma exacerbations vs adjuvant placebo.

Asthma Development in Early Childhood May Hinge on Early Life Stress

Asthma Development in Early Childhood May Hinge on Early Life Stress

Prenatal and early life stress, including societal stress, have been implicated in the development of asthma and other allergic diseases in children.

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