Asthma

Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma

Antibiotic Use During Pregnancy May Increase Risk for Childhood Asthma

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Researchers examined the association of timing, frequency, and class of antibiotic use during pregnancy on the development of childhood asthma.

Sertraline Not Beneficial for Symptomatic Chronic Breathlessness

Sertraline Not Beneficial for Symptomatic Chronic Breathlessness

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Sertraline does not prove to be beneficial for relief of chronic breathlessness.

Efficacy, Safety of Dupilumab in Corticosteroid-Dependent Severe Asthma

Efficacy, Safety of Dupilumab in Corticosteroid-Dependent Severe Asthma

Subcutaneous dupilumab significantly reduced the use of oral corticosteroids in patients with corticosteroid-dependent severe asthma.

Lung Function in Severe Asthma Improved With Benralizumab

Lung Function in Severe Asthma Improved With Benralizumab

Peak expiratory flow increases were greater with benralizumab than placebo in patients with severe eosinophilic asthma.

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

Asthma Risk Increased for Premenopausal Women Using Oral Contraceptives

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Oral contraceptive use in women of reproductive age may increase the risk for lifetime asthma.

Vitamin D Supplementation Improves Asthma Control

Vitamin D Supplementation Improves Asthma Control

In individuals with asthma and vitamin D deficiency, vitamin D supplementation improved asthma control.

Macrolides for Asthma Management: An Updated Review

Macrolides for Asthma Management: An Updated Review

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While macrolides had no direct effect on lung function, their use significantly improved asthma control and quality of life in patients with asthma.

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

Prevalence of Obese, Allergic Asthma Phenotypes Examined in US Children

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The study authors examined data obtained from the 2007-2008 National Survey of Children's Health (NSCH) to determine the prevalence, risk factors, as well as the severity of asthma phenotypes.

Most Concerning Med Issues Explored Among Youth With Asthma

Most Concerning Med Issues Explored Among Youth With Asthma

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The study authors reported, "The most commonly reported problems by youth were: (a) hard to remember when to take the asthma medication (54%) and (b) hard to use asthma medication at school (34%)."

ICS Therapy May Not Be Enough for Asthma Patients With Elevated Eosinophils

ICS Therapy May Not Be Enough for Asthma Patients With Elevated Eosinophils

The study aimed to determine the association between ICS therapy adherence and the occurrence of asthma exacerbations in patients with high blood eosinophil levels.

Feasibility of At-Home Use Injectable Tx for Severe Asthma Assessed

Feasibility of At-Home Use Injectable Tx for Severe Asthma Assessed

Of the total 573 APFS dispensed, 1 malfunctioned and 1 was considered nonfunctional because it was not returned. The study authors also reported that patient-use error only led to 2 unsuccessful at-home administrations.

Type 2 Biomarkers May Predict Exacerbations in Severe Refractory Asthma

Type 2 Biomarkers May Predict Exacerbations in Severe Refractory Asthma

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The positive association between type 2 biomarkers and severe exacerbations in severe refractory asthma may not extend to mild to moderate asthma.

Low Neighborhood Walkability Increases Risk of Asthma in Kids

Low Neighborhood Walkability Increases Risk of Asthma in Kids

Children living in neighborhoods with low walkability are at increased risk of asthma.

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

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Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

Asthma Care Program Improves Provider Documentation, Clinical Measures

Asthma Care Program Improves Provider Documentation, Clinical Measures

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An asthma care program improved implementation of guidelines as well as provider documentation in 65 community centers in 4 states that serve patients with asthma.

Pediatric Asthma Outcomes With Physician Cultural Communication Training

Pediatric Asthma Outcomes With Physician Cultural Communication Training

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Physician asthma care education Plus training resulted in improvements in provider confidence, perceived skill in communicating cross culturally, and short-term asthma-specific outcomes.

Current Smokers With Severe Asthma Distinguished by Sputum Proteomics

Current Smokers With Severe Asthma Distinguished by Sputum Proteomics

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Patients with severe asthma who were current smokers were distinguishable from ex-smokers based on their sputum proteomic level of colony stimulating factor 2.

Children With Status Asthmaticus Do Not Benefit From Magnesium Sulfate

Children With Status Asthmaticus Do Not Benefit From Magnesium Sulfate

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Children with status asthmaticus who received magnesium sulfate therapy were on continuous albuterol for a longer duration.

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

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Asthma and COPD overlap linked to higher prevalence of sleep-related symptoms, including difficulty falling asleep and maintaining sleep, early-morning awakening, and excessive daytime sleepiness.

Early Child Care Attendance and Asthma, Wheeze Risk: What's the Link?

Early Child Care Attendance and Asthma, Wheeze Risk: What's the Link?

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Early child care attendance increased the risk for wheeze in children ≤2 years of age but decreased the risk for asthma in children 3 to 5 years of age.

Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

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Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

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A childhood measles infection may increase the risk for post-bronchodilator airflow obstruction in middle-age adults via its interaction with asthma and smoking.

Early Asthma Symptoms Linked to Lung Function in Adolescents Born Preterm

Early Asthma Symptoms Linked to Lung Function in Adolescents Born Preterm

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Preterm-born children had significantly more frequent preschool wheeze compared with children born at term.

No significant benefit of long-acting muscarinic antagonists over long-acting beta-agonists in reducing exacerbation risk in uncontrolled, persistent asthma

Adjunct long-acting muscarinic antagonist (LAMA) use with corticosteroids was associated with reduced exacerbation risk compared with placebo in patients with uncontrolled, persistent asthma. However, LAMA, long-acting beta-agonist (LABA), and inhaled corticosteroids (triple therapy) were not associated with lower risk for exacerbations compared with LABA and inhaled corticosteroids alone.

Asthma Exacerbation Risk Lower With SMART Therapy

Asthma Exacerbation Risk Lower With SMART Therapy

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In patients with persistent asthma, single maintenance and reliever therapy was associated with a lower risk for exacerbations compared with inhaled corticosteroids as controller therapy and short-acting beta-agonists as relief therapy.

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

Omalizumab Effective in Severe Allergic Asthma, Regardless of Eosinophil Level

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Regardless of blood eosinophil count, omalizumab was an effective treatment in adult and pediatric patients with severe allergic asthma.

Distinct Lung Function Trajectories Associated With COPD Risk

Distinct Lung Function Trajectories Associated With COPD Risk

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Researchers identified 6 distinct FEV1 lung function trajectories, 3 of which were responsible for 75% of the COPD burden.

Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

Antibiotics, Acid-Suppressive Meds Tied to Allergic Disease

Findings for subsequent allergic disease following infant exposure in the first six months of life.

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

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Patients with asthma or chronic obstructive pulmonary disease have especially high rates of nonadherence, even in comparison with other chronic diseases.

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

SCIT May Cut Long-Term Asthma Med Use in Pediatric Allergic Asthma

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In children with allergic asthma, SCIT may reduce long-term asthma medication use.

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