Asthma

Several Asthma, Allergy Groups Express "Deep Concern" Over Epinephrine Inhalation Approval

Several Asthma, Allergy Groups Express "Deep Concern" Over Epinephrine Inhalation Approval

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Several asthma and allergy groups expressed "deep concern" over the recent FDA approval of Primatene MIST.

Epinephrine Inhalation Aerosol Returning to Market as OTC Asthma Inhaler

Epinephrine Inhalation Aerosol Returning to Market as OTC Asthma Inhaler

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The new inhalation delivery system no longer includes CFC. It contains hydrofluroalkane (HFA) propellants and also features a built-in spray indicator and metal canister, replacing the glass container seen with the original Primatene Mist.

Self-Reporting Tool May Be Valid for Asthma Control Assessment in Adolescents

Self-Reporting Tool May Be Valid for Asthma Control Assessment in Adolescents

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The ACCI includes questions about changes in asthma status, perceptions of disease burden, emergency room visits and hospitalizations, steroid use, adherence to prescribed medications, and symptom frequency.

Obesity Linked to Respiratory Infection Risk in Asthma

Obesity Linked to Respiratory Infection Risk in Asthma

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Higher BMI in adults was related to an increase in moderate to severe upper respiratory infections.

Paradoxical Bronchospasm With SABA Therapy: An Underrecognized Adverse Effect

Paradoxical Bronchospasm With SABA Therapy: An Underrecognized Adverse Effect

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Paradoxical bronchoconstriction is an underrecognized adverse event that can occur with administration of β2-agonist-containing inhaler formulations.

Asthma-COPD Overlap Prevalence, Severity in Low- and Middle-Income Countries

Asthma-COPD Overlap Prevalence, Severity in Low- and Middle-Income Countries

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The overall rate of asthma-COPD overlap was 3.8%, with a maximum prevalence of 7.8% in Matlab, Bangladesh.

Chest Radiographs Infrequently Yield Positive Findings in Children With Asthma and Chest Pain

Chest Radiographs Infrequently Yield Positive Findings in Children With Asthma and Chest Pain

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The use of chest radiographs in children with asthma who complain of chest pain should be limited, according to a new study.

Childhood Asthma Risk May Increase With Prenatal Animal Exposure

Childhood Asthma Risk May Increase With Prenatal Animal Exposure

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Children exposed to cats, dogs, goats, cockroaches, and rats while in utero were more likely to develop asthma.

Are Asthma Hospitalizations Predictive of Influenza Hospitalizations in NYC Adults?

Are Asthma Hospitalizations Predictive of Influenza Hospitalizations in NYC Adults?

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Time-series analysis based on geographic location revealed positive significant associations between asthma and influenza hospitalizations in Brooklyn and Manhattan.

Rhinitis Nearly Ubiquitous in Urban Adolescents With Asthma

Rhinitis Nearly Ubiquitous in Urban Adolescents With Asthma

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The majority of study participants had rhinitis at baseline, including perennial allergic rhinitis with seasonal exacerbations, which is the most severe phenotype.

Metered Dose Inhalers in Asthma Lower Hospitalization Rates

Metered Dose Inhalers in Asthma Lower Hospitalization Rates

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Changing to bronchodilator treatment with a metered dose inhaler in patients with mild to moderate asthma resulted in lower hospitalization rates, shorter hospital stays, and a decrease in continuous use of albuterol.

Dupilumab Approved as Add-On Maintenance Tx for Moderate-to-Severe Asthma

Dupilumab Approved as Add-On Maintenance Tx for Moderate-to-Severe Asthma

The FDA has approved Dupixent as an add-on maintenance treatment in patients with moderate-to-severe asthma aged 12 years and older with an eosinophilic phenotype or with oral corticosteroid-dependent asthma.

Asthma Risk in Infants Predicted by Total Serum Bilirubin

Asthma Risk in Infants Predicted by Total Serum Bilirubin

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Total serum bilirubin levels of 9 to 11.9 mg/dL, 12 to 14.9 mg/dL, and 15 to 17.9 mg/dL were associated with significantly greater risks for asthma in infants.

Childhood Non-Atopic Rhinitis Increases Adult Asthma Risk

Childhood Non-Atopic Rhinitis Increases Adult Asthma Risk

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Childhood non-atopic rhinitis is associated with an increased risk for adult asthma.

Early-Onset Asthma/Wheezing Associated With Later Childhood Obesity

Early-Onset Asthma/Wheezing Associated With Later Childhood Obesity

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Children with asthma had a 66% higher risk for incident obesity compared with children without asthma.

Gas Trapping Improved With Bronchial Thermoplasty in Severe Asthma

Gas Trapping Improved With Bronchial Thermoplasty in Severe Asthma

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Bronchial thermoplasty reduced gas trapping in individuals with asthma, particularly in patients with severe disease.

Pulmonary Symptoms With GERD in Infants May Increase Asthma Risk

Pulmonary Symptoms With GERD in Infants May Increase Asthma Risk

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Infants who presented with pulmonary symptoms when diagnosed with gastroesophageal reflux disease had a higher incidence of early onset asthma compared with infants who did not have pulmonary symptoms.

Lung Function Improved With Dupilumab in Adolescents With Asthma

Lung Function Improved With Dupilumab in Adolescents With Asthma

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Adolescents with asthma treated with dupilumab experienced significant improvements in FEV1 compared with placebo.

Omalizumab Improves Lung Function in Persistent Allergic Asthma

Omalizumab Improves Lung Function in Persistent Allergic Asthma

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Patients with moderate to severe persistent allergic asthma who were treated with omalizumab experienced greater improvements in lung function after 16 weeks compared with those treated with placebo.

Montelukast Plus Levocetirizine vs Monotherapy in Asthma, Allergic Rhinitis

Montelukast Plus Levocetirizine vs Monotherapy in Asthma, Allergic Rhinitis

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Montelukast plus levocetirizine demonstrated a significant reduction in mean daytime nasal symptom scores compared with montelukast monotherapy.

Severe Eosinophilic Asthma Effectively Managed With Benralizumab

Severe Eosinophilic Asthma Effectively Managed With Benralizumab

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Benralizumab was associated with a significant reduction in annual asthma exacerbation rates.

Complementary Alternative Medicine in Asthma Use Varies Among Racial/Ethnic Groups

Complementary Alternative Medicine in Asthma Use Varies Among Racial/Ethnic Groups

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Black and Hispanic respondents with asthma were less likely to use complementary alternative medicine than their white counterparts.

Inhaled Corticosteroid Therapy Refill Disruption Leads to Exacerbations

Inhaled Corticosteroid Therapy Refill Disruption Leads to Exacerbations

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Disrupting regular combination inhaled corticosteroid therapy refills increased hospitalizations and exacerbations.

Asthma Severity Does Not Affect Overall Asthma Control in Children

Asthma Severity Does Not Affect Overall Asthma Control in Children

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Regardless of severity, when children's asthma was appropriately managed according to guidelines, they experienced significant improvements.

Higher Childhood Asthma Risk From Recurring Acute Respiratory Infections

Higher Childhood Asthma Risk From Recurring Acute Respiratory Infections

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A higher number of acute respiratory infections before the age of 2 may increase the risk for asthma by age 7.

Reduced Perinatal Proteobacteria Exposure Linked to Childhood Wheezing

Reduced Perinatal Proteobacteria Exposure Linked to Childhood Wheezing

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Lower exposure to Proteobacteria in umbilical cord serum was associated with an increased risk for childhood wheezing.

Asthma Improved in African American Adolescents Using Comprehensive Treatment Plan

Asthma Improved in African American Adolescents Using Comprehensive Treatment Plan

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African-American adolescents with asthma had improved outcomes when they received a comprehensive treatment plan.

Metered Dose Inhaler Errors Affect Many With COPD and Asthma

Metered Dose Inhaler Errors Affect Many With COPD and Asthma

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The most common error related to the use of metered dose inhalers was the failure to attach the inhaler to a spacer.

Xolair Prefilled Syringe Formulation Gets FDA Approval

Xolair Prefilled Syringe Formulation Gets FDA Approval

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The PFS formulation eliminates the need to reconstitute the solution before administration.

Paraben Exposure and Childhood Asthma-Related Outcomes

Paraben Exposure and Childhood Asthma-Related Outcomes

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For every 10-fold rise in methyl and propyl concentrations, there was a 2.61 and a 2.18 increased prevalence odds ratio, respectively, of reporting an emergency department visit in the last 12 months in boys with asthma.

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