Anna K Fuzery, William Clarke

All articles by Anna K Fuzery, William Clarke

At a Glance Organophosphate poisoning is the result of acute or chronic exposure to one of more than forty organophosphate insecticides currently in use. Organophosphates inhibit cholinesterase enzymes, including red blood cell (RBC) cholinesterase and plasma cholinesterase, thereby preventing the breakdown of acetylcholine. Excessive acetylcholine accumulation initially produces stimulatory and subsequently inhibitory effects on neurotransmission.…