Early Bactericidal Activity of High-Dose Isoniazid for Drug Resistant TB
Daily doses of 10 to 15 mg/kg isoniazid demonstrated similar activity against tuberculosis (TB) strains with inhA mutations as 5 mg/kg doses against drug-sensitive strains.
All articles by Bradley van Paridon
Association Between GI and Respiratory Illness, Income, and School Absenteeism
During the period from 2010 to 2016, parents of children from low-income households were more likely to report recent childhood GI and respiratory illnesses than parents with a higher income.
Vitamin C, Hydrocortisone, Thiamine Not Superior to Hydrocortisone Alone for Septic Shock
For patients with septic shock, treatment with intravenous vitamin C, hydrocortisone, and thiamine did not significantly improve the duration of survival and free of vasopressor administration over 7 days.
Microbiologic Failure in the Setting of Clinical Cure of Bacterial Pneumonia
Microbiologic treatment failure was found to be independently associated with recurrent pneumonia or death among patients with bacterial pneumonia after clinical cure.
Updated Recommendations on the Use of Anthrax Vaccine in the United States
The CDC’s Prevention’s Advisory Committee on Immunization Practices updated recommendations regarding the use of anthrax vaccine in the US.
Diversity of Mycobacterium abscessus Subclones in Pediatric Cystic Fibrosis
Sputum isolates of Mycobacterium abscessus may not reflect a patient’s full bacterial diversity.
Surveillance Definitions for Nonventilator Hospital-Acquired Pneumonia
The objective surveillance for nonventilator hospital-acquired pneumonia (HAP) via electronically computable definitions generates incidence, mortality, and adjusted odds ratios [OR] for hospital mortality similar to those generated by manual surveillance.
Early-Onset Pneumonia in Recipients of Liver Transplant
Early-onset pneumonia with multidrug-resistant organisms is a major concern for patients who have received a liver transplant, and pre- and intra-operative risk factors influence its development, according to study data presented at The American Association for the Study of Liver Diseases’ The Liver Meeting, held November 8 to 12, 2019 in Boston, Massachusetts. In an…
Infant Respiratory Syncytial Virus Bronchiolitis, Pneumonia Risks
The development of respiratory syncytial virus bronchiolitis in infants within the first 6 months of life was associated with increased odds of pneumonia, otitis media, and filling of antibiotic prescriptions in the second 6 months of life.
Treatment-Decision Score for Children With HIV and Suspected Tuberculosis
A new treatment-decision score for the diagnosis of TB in children with HIV performed well, and when used in an algorithm may facilitate prompt treatment decision making for children at a high risk for mortality.
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