Bradley van Paridon

A new sepsis screening tool developed using machine learning was timelier and more discriminating than several benchmark screening tools.

New data demonstrate the potential of the Accelerate Pheno™ system to improve antimicrobial use and stewardship.

A double-blind trial found omadacycline to be noninferior to moxifloxacin for the treatment of community-acquired bacterial pneumonia.

The incidence of pneumococcal sepsis in children remained substantial after the introduction of the pneumococcal conjugate vaccine in Switzerland.

A deep-learning algorithm performed better than radiologists at detecting active pulmonary tuberculosis on chest radiographs.

Procalcitonin-guided antibiotic management resulted in lower antibiotic exposure while maintaining similar mortality rates in patients with bacteremia.

Pediatric histoplasmosis most frequently manifests as pulmonary disease, and the highest diagnostic yields were achieved when multiple diagnostic modalities were used.

An investigation into an outbreak of NDM-producing Klebsiella pneumoniae across 2 Belgian hospitals identified an outpatient clinic as the likely common site of transfer and highlights the importance of infection control measures in outpatient settings.

The incidence of lung cancer remains increased 5 years after smoking cessation.

The real-world effectiveness of PCV13 vaccine in preventing hospitalization for vaccine-type community-acquired pneumonia was assessed.

Adult caretaker influenza vaccination cocooning programs can prove beneficial and financially successful in private practice models where external funding is limited or not available.

Among children there was an increased risk for acute respiratory illness caused by noninfluenza respiratory pathogens following influenza vaccination compared to unvaccinated children during the same period.

Researchers assessed the relationship between prevention of RSV in preterm infants and the frequency of subsequent wheeze in childhood.

Further research on rapid tests is warranted, as industry-sponsored research tends to favor the industry’s product and affects how physicians practice medicine.

Use of prophylactic antimicrobial therapy was not associated with a reduction in mortality or transfer to critical care compared with patients managed with supportive care only.

Shorter treatment regimens for tuberculosis were associated with increased completion rates and fewer adverse events compared with traditional regimens.

Overprescription for uncomplicated acute bronchitis is common despite guidelines recommending against it.