Multiple Myeloma
Multiple Myeloma I. What every physician needs to know. Multiple myeloma is a hematologic malignancy characterized by clonal bone marrow plasma cells and monoclonal protein in the serum or urine. Symptomatic myeloma is associated with hypercalcemia, renal insufficiency, anemia, and bone disease manifested as bony pain (classically back pain) or atraumatic fractures. The symptoms and…