Elliott Vichinsky

All articles by Elliott Vichinsky

Sickle cell syndromes

Sickle cell syndromes What every physician needs to know: Sickle cell disease (SCD) is an inherited, chronic, hemolytic anemia characterized by acute episodes of vaso-occlusion and progressive organ dysfunction. The disease results from mutation in the beta globin chain, leading to production of sickle hemoglobin. Sickle hemoglobin polymerizes and results in fragile, deformed red cells…

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