Severe congenital neutropenia
Severe congenital neutropenia What every physician needs to know: Severe congenital neutropenia (SCN) is a rare heterogenous disorder characterized by chronic severe neutropenia (absolute neutrophil count [ANC] less than 500/uL) and arrest of neutrophil maturation at the promyelocyte/myelocyte stage, due to a constitutional genetic defect. Patients with SCN are usually diagnosed in the first year…