M. Freer James

All articles by M. Freer James


Ascites I. Problem/Condition. Ascites is the accumulation of fluid in the peritoneal cavity, usually resulting from cirrhosis. Only cirrhotic patients with portal hypertension (HTN) develop ascites, and portal HTN can also lead to the development of ascites in patients with conditions other than cirrhosis. Portal HTN results in activation of the renin-angiotensin-aldosterone system, sympathetic nervous…

Spontaneous bacterial peritonitis

Spontaneous bacterial peritonitis I. What every physician needs to know. Spontaneous bacterial peritonitis (SBP) is an infection of ascites that occurs in the absence of an identified intra-abdominal source of infection, such as intestinal perforation or abscess. Bacteria are felt to translocate across the bowel wall, seeding lymph nodes and ultimately ascites, and host factors…

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