Naveed Saleh

In recent decades, a sea change in our understanding of pulmonary arterial hypertension has affected treatment approaches, prognosis, and the patient journey.

What kinds of pulmonary sequelae do patients experience a year after hospitalization with COVID-19 pneumonia — and does the level of ventilatory support matter?

The SHIP + CT clinical trial compared the effect of isotonic vs inhaled hypertonic saline on lung structure in children with cystic fibrosis over 48 weeks.

A systematic review identified risk factors for COPD among those who have never smoked.

How effective are the 3 most commonly used pulmonary arterial hypertension risk assessment tools — REVEAL, COMPERA, and FPHR — in predicting mortality risk?

What is the recovery potential of patients with COVID-19-associated respiratory failure who receive mechanical ventilation?

What effect does BMI have on treatment response in patients with pulmonary arterial hypertension?

Can nonsevere childhood community-acquired pneumonia be effectively treated by a short-course of antibiotics?

Researchers identified tuberculosis endotypes and their associated, distinctive clinical outcomes and patterns of gene expression.

Is pulmonary hypertension more prevalent and/or severe in individuals with COPD who live at high altitudes?

Investigators examined the relationship between low-dose aspirin and incidence of lung cancer in patients with COPD.

A recent survey of patients with aspirin-exacerbated respiratory disease identified trends in patients’ medication use and treatment experience.

Is the inflammatory response of COVID-19 related to cellular senescence and its associated proinflammatory phenotype?

What is the optimal timing of tracheostomy in overburdened health care systems during viral epidemics?

In COPD, how early in the disease process should clinician assess patients for balance impairment issues?

Chinese researchers assessed VTE and bleeding risk among patients with COVID-19 who were critically ill, as well as associated risk factors.

Is a peer-led asthma self-management program more effective than an adult-led program in improving asthma outcomes in adolescents in urban areas?

Is preserved ratio impaired spirometry (PRISm) associated with adverse clinical outcomes relative to normal spirometry?

A proposed algorithm for discontinuing biologics looks at asthma symptoms, exacerbations, OCS use, spirometry results, T2 inflammation, and comorbidies.

What are the characteristics of those hospitalized for COVID-19 who have asthma, and how does use of inhaled corticosteroids affect their outcomes?

Can peak oxygen uptake, as measured via cardiopulmonary exercise testing, predict mortality in patients with COPD?

Can proteomics identify biomarkers of infection, disease severity, and treatment
response in patients with non-tuberculous mycobacterial lung infection?

Swiss researchers studied pediatric patients with cystic fibrosis to determine their functional response to nebulized inhalation with salbutamol.

Can blockade of the interleukin-1 or IL-6 pathways shorten the time to clinical improvement in patients with COVID-19 or hypoxic respiratory failure?

Researchers investigated the relationship between inflammation and OSA severity, as measured by oxygen saturation and the apnea–hypopnea index.

In patients with severe COPD who are hypoxemic, which is better for walking endurance, an automatically titrating O2 system or a constant flow system?

A UK study examined the effect of socioeconomic disparities on adults with asthma.

An exploratory study assessed use of high flow nasal therapy to reduce moderate to severe COPD exacerbations in patients recently hospitalized for AECOPD.

Are CURB-65 and PSI effective predictors of inpatient COVID-19 mortality, and would added measures for d-dimer and procalcitonin improve their predictive value?

Investigators evaluated a hospital protocol change allowing administration of nasal high flow therapy outside the ICU in COPD with acute hypoxic respiratory failure.