Ron Goldberg

Can the unique characteristics of a particular patient with severe asthma predict whether that patient will respond to biologic treatment with mepolizumab?

Investigators compared COPD clinical and cost outcomes in patients using fixed-dose LAMA/LABA dual therapy vs FF+UMEC+VI triple therapy.

Researchers determined predictors of depression in those with asthma and analyzed the trajectory of their depressive symptoms from adolescence through adulthood.

A clinical trial assessed cardiovascular and pulmonary responses in those who vaped or smoked cigarettes vs those who did not via a 15-minute product-use challenge.

A meta-analysis of patients with multi-drug-resistant TB identified the pooled proportion of patients with extensively drug-resistant TB and pre-XDR-TB.

Investigators examined how lifestyle factors affected an individual’s risk for developing IPF and how genetic susceptibility to IPF modified lifestyle risk factors.

Researchers investigated whether positive airway pressure therapy improved glycemic variability in patients with type 2 diabetes and moderate-to-severe OSA.

Investigators assessed the association between vaping in adolescents and subsequent smoking of cigarettes on an ongoing basis several years after starting to vape.

The DENALI trial assessed whether each component drug of the albuterol-budesonide pMDI were safe and contributed to the therapy’s efficacy, as required by the FDA.

Investigators detailed a balloon pulmonary angioplasty program for patients with CTEPH unwilling or unable to undergo pulmonary thromboendarterectomy.

Researchers assessed whether influenza vaccine effectiveness was affected by statin use, and whether statin use was associated with influenza infection.

Investigators assessed the prevalence of drug hypersensitivity reactions that affect health-related quality of life and mental health, as well as associated risk factors.

A phase 3 trial assessed ravulizumab, a terminal complement C5 inhibitor and an add-on COVID-19 therapy, for treating patients with severe COVID-19 needing ventilation.

Climate change concerns prompted researchers to examine associations between lung function in newborns and prenatal/postnatal heat or cold exposure.

A clinical trial of ELX/TEZ/IVA in children with CF aged 2 to 5 years assessed the CFTR modulator’s pharmacokinetics, pharmacodynamics, efficacy, and safety.

A meta-analysis examined outcomes of patients with lung cancer at high risk for acute exacerbations and in-hospital mortality due to underlying IPF and UIP.

Investigators assessed whether adults with asthma and obesity were more likely to have airway inflammation, systemic inflammation, and adipokines.

Researchers examined demographic and other factors influencing the incidence rate of asthma with recurrent exacerbations among US children and adolescents.

Researchers assessed the correlation between pulmonary function and bone mineral density in healthy US adults, also assessing correlations by age, sex, and race.

A study was conducted to determine the relationship between changes in NT-proBNP levels and risk for heart failure and death.

Researchers assessed how mid-childhood dietary patterns — eg, a health-conscious vs a processed food diet — affected lung function and incident asthma in adolescence.

Researchers assessed whether early treatment with hydrocortisone reduced 28-day mortality in patients in the ICU with severe community-acquired pneumonia.

Researchers compared the effects of low-calorie, low-protein feeding vs standard-calorie, standard-protein feeding during the acute phase of critical illness.

Researchers sought to describe adverse event tolerability regarding acne, headache, and gastrointestinal events for baricitinib in patients with moderate-to-severe atopic dermatitis.

Investigators assessed whether use of montelukast in adults with asthma is associated with onset of neuropsychiatric adverse events.

Investigators assessed the effect of long-term oral N-acetylcysteine (NAC) therapy on the rate of acute exacerbations in patients with COPD.

Investigators assessed the clinical impact of testing hospitalized patients with rapid sample-to-answer multiplex PCR testing for respiratory viruses.

A post hoc clinical trial analysis assessed the efficacy of once-daily, fixed-dose MF/IND/GLY in patients with asthma, with and without persistent airflow limitation.

Investigators in Sweden assessed whether the interaction of patients’ smoking and socioeconomic statuses could predict their risk for respiratory diseases.

Researchers conducted a prospective study of RSV incidence and severity in adults during 2 seasons from 2019 to 2021— during the start and middle of the pandemic.