Lack of Uniform Asthma-COPD Overlap Definition Creates Treatment Challenges
The prevalence of asthma-COPD overlap is highly variable, depending on the definition used at the time of diagnosis.
All articles by Sheila Jacobs
Latent TB Detection: QuantiFERON-TB Gold Plus vs QuantiFERON-TB Gold In-Tube
Positive results with respect to the presence of latent tuberculosis infection in patients with renal failure were more consistent with the use of QuantiFERON-TB Gold Plus testing compared with the use of QuantiFERON-TB Gold In-Tube testing.
Dry Powder Formulation of Treprostinil Appears Safe, Tolerable in PAH
Use of the dry powder formulation of treprostinil, known as LIQ861, has demonstrated safety and tolerability in patients with pulmonary arterial hypertension beyond 2 weeks.
Novel Pediatric-Automated Respiratory Score Feasible in Children With Asthma
The creation of a novel pediatric-automated respiratory score is a feasible option to standardize pediatric intensive care unit management of patients with acute asthma exacerbations.
High Concentration Oxygen Therapy in Pediatric Asthma Leads to Higher CO2 Levels
In pediatric patients with moderate to severe asthma exacerbations, a titrated oxygen regimen that only administers oxygen therapy to patients with proven hypoxemia should be considered.
Can Quantitative CT Measure Disease Severity in Postinfectious Bronchiolitis?
Effective quantitative airway measurements and air-trapping evaluations based on chest computed tomography scans are technically feasible in pediatric patients with postinfectious bronchiolitis obliterans.
Is CPAP or Noninvasive Ventilation Preferred in Obesity Hypoventilation Syndrome?
Although both noninvasive ventilation and CPAP appear to exhibit similar long-term effectiveness in obesity hypoventilation syndrome, CPAP is thought to be the preferred first-line treatment modality because of its lower complexity and cost.
Progressive Skin Fibrosis in SSc Associated With Lung Function Decline
In patients with diffuse cutaneous systemic sclerosis, developing progressive skin fibrosis within 1 year is associated with a decline in lung function and worse survival.
Circulating Mast Cell Progenitors in Allergic Asthma Linked to Reduced Lung Function
In young adults with allergic asthma, elevated levels of circulating mast cell progenitors are linked to reduced lung function and high levels of fibroblast growth factor-21.
Could Spectral Detector CT Offer Accurate Diagnosis of CTEPH?
The use of spectral-detector computed tomography offers a highly accurate method to diagnose chronic thromboembolic pulmonary hypertension.
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