Chronic Obstructive Pulmonary Disease (COPD)

Incident Diuretic Use May Increase Adverse Events in COPD

Incident Diuretic Use May Increase Adverse Events in COPD

Incident diuretic use was associated with increased rates of respiratory-related morbidity and mortality in older adults with chronic obstructive pulmonary disease.

Mortality Rates Compared Between Extrafine ICS-Containing vs ICS-Free Medications

Mortality Rates Compared Between Extrafine ICS-Containing vs ICS-Free Medications

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The pooled safety analysis included data from the TRILOGY, TRINITY, and TRIBUTE studies.

Assessing Depression Following Inpatient COPD Rehabilitation

Assessing Depression Following Inpatient COPD Rehabilitation

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PHQ-9 and PHQ-2 show factorial validity, invariance, and reliability for measuring depression in patients with chronic obstructive pulmonary disease.

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

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Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative care consultation was linked to a reduction in hospital costs for hospitalized adults with serious illness, such as COPD.

Survival Predictors When Life Support Is Withheld in ICU

Survival Predictors When Life Support Is Withheld in ICU

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Survival at 6 months was significantly associated with acute respiratory failure and history of COPD.

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

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A higher proportion of patients with COPD and a blood eosinophil count of ≥0.34×109/L had elevated markers of low-grade systemic inflammation regardless of forced expiratory volume in 1 second.

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

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Readmission rates were highest during the first 72 hours after admission for an acute exacerbation of chronic obstructive pulmonary disease.

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

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Adding olodaterol to tiotropium did not significantly reduce exacerbations in patients with chronic obstructive pulmonary disease as much as researchers had anticipated.

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

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Asthma and COPD overlap linked to higher prevalence of sleep-related symptoms, including difficulty falling asleep and maintaining sleep, early-morning awakening, and excessive daytime sleepiness.

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

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The drug consists of fluticasone furoate, an inhaled corticosteroid (ICS), umeclidinium, a long-acting muscarinic antagonist, and vilanterol, a long-acting beta2-adrenergic agonist (LABA), delivered via an Ellipta dry powder inhaler.

Transcatheter vs Surgical Aortic Valve Replacement in COPD

Transcatheter vs Surgical Aortic Valve Replacement in COPD

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In patients with COPD, transcatheter aortic valve replacement was associated with fewer respiratory-related complications than surgical aortic valve replacement.

Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

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Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple therapy with fluticasone furoate, umeclidinium, and vilanterol was associated with a lower rate of exacerbations in chronic obstructive pulmonary disease.

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

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A childhood measles infection may increase the risk for post-bronchodilator airflow obstruction in middle-age adults via its interaction with asthma and smoking.

Cardiovascular Complications of COPD

Cardiovascular Complications of COPD

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A 55-year-old man with chronic obstructive pulmonary disease reports having some mild chest pain.

Perioperative Risk Assessment in a Patient With COPD

Perioperative Risk Assessment in a Patient With COPD

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A 64-year-old man with chronic obstructive pulmonary disease, diabetes, chronic kidney disease, and morbid obesity seeks preoperative approval for femoral popliteal bypass surgery.

Fixed-Dosed Dual Bronchodilators for COPD: Overview and Clinician Interview

Fixed-Dosed Dual Bronchodilators for COPD: Overview and Clinician Interview

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Treating chronic obstructive pulmonary disease remains challenging, particularly in terms of choosing the appropriate fixed-dose combination bronchodilator.

COPD Risk Predicted by Large Airway Dimensions on Computed Tomography

COPD Risk Predicted by Large Airway Dimensions on Computed Tomography

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Greater Pi10 was associated with incident spirometry-defined chronic obstructive pulmonary disease in a general population-based sample without clinical lung disease.

Tai Chi Helps Improve Respiratory Function in COPD

Tai Chi Helps Improve Respiratory Function in COPD

Tai chi found to be as effective as pulmonary rehabilitation for patients with chronic obstructive pulmonary disease.

Debating Noninvasive vs Invasive Ventilation in Acute Exacerbations of COPD

Debating Noninvasive vs Invasive Ventilation in Acute Exacerbations of COPD

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It is still not known whether differences in mortality rates between patients who receive noninvasive vs invasive ventilation for acute exacerbations of COPD can be attributed to less severe disease or other factors.

Distinct Lung Function Trajectories Associated With COPD Risk

Distinct Lung Function Trajectories Associated With COPD Risk

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Researchers identified 6 distinct FEV1 lung function trajectories, 3 of which were responsible for 75% of the COPD burden.

Lonhala Magnair Now Available for Long-Term COPD Maintenance

Lonhala Magnair Now Available for Long-Term COPD Maintenance

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Lonhala Magnair is available as a 25mcg strength inhalation solution per 1mL vial.

Simple Lung Function Tests in Primary Care Help ID Early COPD

Simple Lung Function Tests in Primary Care Help ID Early COPD

Peak flow meter, microspirometry are optimal, with full spirometry for positive results.

Sleep Quality in COPD May Predict Overall Quality of Life

Sleep Quality in COPD May Predict Overall Quality of Life

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Sleep quality in patients with chronic obstructive pulmonary disease may be a significant predictor of multiple metrics of quality of life.

Two Inhalers Go Head-to-Head in COPD Exacerbation Study

Two Inhalers Go Head-to-Head in COPD Exacerbation Study

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Study authors concluded, "Combining tiotropium and olodaterol did not reduce exacerbation rate as much as expected compared with tiotropium alone."

COPD: Disease Management Care vs Recommended Care Alone

COPD: Disease Management Care vs Recommended Care Alone

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Disease management added to recommended care in chronic obstructive pulmonary disease was not superior to recommended care alone.

Efficacy of Different Doses of Glycopyrronium Via a Metered Dose Inhaler in COPD

Efficacy of Different Doses of Glycopyrronium Via a Metered Dose Inhaler in COPD

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Four different doses of glycopyrronium delivered via metered dose inhaler were compared for safety and efficacy in the treatment of chronic obstructive pulmonary disease.

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

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Patients with asthma or chronic obstructive pulmonary disease have especially high rates of nonadherence, even in comparison with other chronic diseases.

Specific COPD Questionnaire Cutoff Threshold May Identify More Symptomatic Patients

Specific COPD Questionnaire Cutoff Threshold May Identify More Symptomatic Patients

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The Clinical COPD Questionnaire cutoff point of 1.4 demonstrated a better agreement with other COPD measures in patients with more symptomatic disease.

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