Chronic Obstructive Pulmonary Disease

Inflammatory Markers in COPD Linked to Increased Symptom Burden in Smokers

Inflammatory Markers in COPD Linked to Increased Symptom Burden in Smokers

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Inflammatory markers associated with COPD were linked to increased symptom burden, a greater number of exacerbations, and decreased 6-minute walk distance in smokers with preserved spirometry.

Advair Diskus Generic Now Available for COPD and Asthma

Advair Diskus Generic Now Available for COPD and Asthma

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Wixela Inhub has been made available by Mylan for the treatment of asthma and COPD.

COPD False Positive Diagnosis Found in the Majority of Study Cases

COPD False Positive Diagnosis Found in the Majority of Study Cases

COPD is prone to false positive diagnoses.

Comprehensive Research Bronchoscopy Procedure Safe, Tolerable in COPD

Comprehensive Research Bronchoscopy Procedure Safe, Tolerable in COPD

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A comprehensive research bronchoscopy procedure, including oral sampling, bronchoalveolar lavage, endobronchial biopsy, and brushing can be safely performed in COPD.

Triple Therapy Reduces COPD Exacerbation Risk Compared With Dual Therapy

Triple Therapy Reduces COPD Exacerbation Risk Compared With Dual Therapy

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Compared with dual therapy, triple therapy was associated with reduced risk for severe exacerbation of COPD and better FEV1.

First Generic Version of Advair Diskus Gets FDA Approval

First Generic Version of Advair Diskus Gets FDA Approval

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Mylan plans to make Wixela Inhub available in 3 strengths: 100mcg/50mcg, 250mcg/50mcg, and 500mcg/50mcg.

COPD Common Condition in Frequent Users of Emergency Department

COPD Common Condition in Frequent Users of Emergency Department

Nearly 6% of older adults account for more than 20% of emergency department visits.

Indacaterol/Glycopyrronium Improves Regional Ventilation in COPD

Indacaterol/Glycopyrronium Improves Regional Ventilation in COPD

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In patients with moderate to severe COPD, indacaterol/glycopyrronium treatment is associated with improvements in regional ventilation and pulmonary microvascular blood flow.

DASS-21 Demonstrates Validity, Responsiveness in COPD

DASS-21 Demonstrates Validity, Responsiveness in COPD

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The Depression, Anxiety, and Stress Scale (DASS-21) demonstrated validity in individuals with COPD underwent an 8-week pulmonary rehabilitation program.

COPD Exacerbations May Be Reduced With Vitamin D

COPD Exacerbations May Be Reduced With Vitamin D

The review showed supplementation was only effective for baseline vitamin D levels <25 nmol/L.

Cardiovascular Comorbidity Screening Should Be Conducted in COPD With Obesity

Cardiovascular Comorbidity Screening Should Be Conducted in COPD With Obesity

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Hypertension and diabetes are especially prevalent comorbidities in obese patients with chronic obstructive pulmonary disease.

Influenza Vaccine Cuts Flu-Related Hospitalization in COPD

Influenza Vaccine Cuts Flu-Related Hospitalization in COPD

Influenza-positive patients have higher rates of crude mortality and critical illness vs influenza-negative patients.

Hypercapnic COPD Survival, Clinical Outcomes With High-Intensity NIV

Hypercapnic COPD Survival, Clinical Outcomes With High-Intensity NIV

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Patients with comorbid stable COPD and chronic hypercapnic respiratory failure have improved symptoms and survival rates with high-intensity noninvasive ventilation.

Keeping Up-to-Date on COPD Controversies: A Clinician Interview

Keeping Up-to-Date on COPD Controversies: A Clinician Interview

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The GOLD scientific committee published a report on current controversies in COPD, including the role of cigarette smoking vs biomass exposure, the role of thoracic imaging, and different treatment strategies.

Overlap Syndrome in COPD and OSA Is Up 4-Fold in Medicare Beneficiaries

Overlap Syndrome in COPD and OSA Is Up 4-Fold in Medicare Beneficiaries

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The prevalence of overlap syndrome in obstructive sleep apnea and COPD in Medicare beneficiaries increased 4-fold from 2004 to 2013.

COPD Assessment Test May Help Determine Severity of Bronchiectasis

COPD Assessment Test May Help Determine Severity of Bronchiectasis

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The COPD assessment test proved to be valid and reproducible in assessing the impact effect and severity of bronchiectasis symptoms in patients with COPD.

COPD and Obesity: Is There a Dose-Response Relationship in Nonsmokers?

COPD and Obesity: Is There a Dose-Response Relationship in Nonsmokers?

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The odds of developing COPD were considerably higher in both men and women with class III obesity compared with normal weight individuals.

Anxiety in COPD Benefits From Cognitive Behavioral Therapy vs Self-Help

Anxiety in COPD Benefits From Cognitive Behavioral Therapy vs Self-Help

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Cognitive behavioral therapy interventions were statistically and clinically superior to self-help leaflets in the treatment of anxiety in patients with COPD.

Frailty Linked to Poor Health Outcomes in COPD

Frailty Linked to Poor Health Outcomes in COPD

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Patients with COPD who were considered frail were more likely to have lower quality of life, increased rate and length of hospitalization, and a higher rate of mortality.

Self-Management Support Improves Quality of Life in COPD

Self-Management Support Improves Quality of Life in COPD

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Compared with usual care, a comprehensive 3-month program combining transition and long-term self-management support for patients with COPD led to significantly fewer COPD-related hospitalizations and greater quality of life.

COPD Tied to Obesity in Never-Smokers

COPD Tied to Obesity in Never-Smokers

A strong dose-response relationship was seen in never-smokers aged 50 and older.

COPD Short-Term Outcomes Predicted by Risk Scale

COPD Short-Term Outcomes Predicted by Risk Scale

Ottawa COPD Risk Scale is valid for predicting short-term serious outcomes for patients in the emergency department.

Blood Eosinophilia-Targeted COPD Treatment: LABA-ICS vs LAMAs

Blood Eosinophilia-Targeted COPD Treatment: LABA-ICS vs LAMAs

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Blood eosinophil concentrations could be used to target patients with chronic obstructive pulmonary disease who are likely to respond to initial long-acting bronchodilator therapy.

COPD Prevalence Higher in Poor and Rural Communities

COPD Prevalence Higher in Poor and Rural Communities

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Living in a rural community was a predictor for COPD prevalence, whether the individual had a history of smoking or was a current smoker.

COPD May Predict Mortality in Ventricular Tachyarrhythmias, Sudden Cardiac Arrest

COPD May Predict Mortality in Ventricular Tachyarrhythmias, Sudden Cardiac Arrest

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The presence of COPD is linked to higher all-cause mortality and cardiac death at 24 hours in high-risk patients who present with ventricular tachyarrhythmias and sudden cardiac arrest.

Sputum Microbiome May Predict Prognosis After COPD Hospitalization

Sputum Microbiome May Predict Prognosis After COPD Hospitalization

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Decreasing alpha diversity in the microbiome profile of sputum samples of patients hospitalized with COPD acute exacerbations was associated with increased 1-year mortality.

COPD, Nocturnal Hypoxemia May Increase CV Events in Women With Suspected OSA

COPD, Nocturnal Hypoxemia May Increase CV Events in Women With Suspected OSA

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Nocturnal hypoxemia, along with COPD, increased the risk for cardiovascular events and mortality in female patients with suspected obstructive sleep apnea.

Traveling by Airplane With COPD: Expert Advice

Traveling by Airplane With COPD: Expert Advice

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Healthcare providers should educate all patients with COPD about their flight-related risks and the need to seek medical advice before flying.

Endobronchial Valve Therapy: A Nonsurgical Option for Advanced Emphysema

Endobronchial Valve Therapy: A Nonsurgical Option for Advanced Emphysema

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Bronchoscopic lung volume reduction with valve replacement shows the most promise for improving lung function, exercise tolerance, and quality of life in patients with advanced emphysema.

Which Drug Combination Works Best to Reduce Acute COPD Exacerbations?

Which Drug Combination Works Best to Reduce Acute COPD Exacerbations?

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Compared with a combination treatment of LABA/LAMA, ICS/LABA/LAMA combination therapy was associated with a significantly greater pooled risk reduction in COPD exacerbation.

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