COPD Archive

Umeclidinium/Vilanterol Efficacy Assessed in Elderly COPD Patients

Umeclidinium/Vilanterol Efficacy Assessed in Elderly COPD Patients

Study authors performed a post hoc pooled analysis of data from 10 trials to assess the safety and efficacy of umeclidinium/vilanterol in elderly symptomatic patients with COPD.

GERD and Nasal Symptoms Affect Bronchitis Symptom Severity in COPD

GERD and Nasal Symptoms Affect Bronchitis Symptom Severity in COPD

Gastroesophageal reflux disease is associated with an increase in bronchitis symptoms in patients with COPD.

Prolonged Leisure-Time Sitting Tied to Increased COPD Mortality Risk

Prolonged Leisure-Time Sitting Tied to Increased COPD Mortality Risk

Increase in all-cause, cardiovascular disease, cancer, diabetes, kidney disease, suicide, and COPD mortality.

FDA Approves Zephyr Endobronchial Valve for Treating Severe Emphysema

FDA Approves Zephyr Endobronchial Valve for Treating Severe Emphysema

The approval was based on results from a multicenter study (LIBERATE) of 190 patients with severe emphysema.

Use of Palliative Care, Oxygen Therapy Increasing for COPD

Use of Palliative Care, Oxygen Therapy Increasing for COPD

For patients with advanced COPD, the use of formal palliative care services and long-term oxygen therapy has increased but remains low.

Clinical Effect of Emphysema in Individuals With HIV

Clinical Effect of Emphysema in Individuals With HIV

The clinical significance of emphysema was greater in people living with HIV vs those without HIV.

COPD End-of-Life Management Strategies: Use Could Be Expanded

COPD End-of-Life Management Strategies: Use Could Be Expanded

The use of formal palliative care services among patients with chronic obstructive pulmonary disease increased by 1% per year, going from 5.3% in 2004 to 14.3% in 2014.

Patient With COPD, Smoking History Presents to ED With Sensory Loss

Patient With COPD, Smoking History Presents to ED With Sensory Loss

A 72-year-old man with a 50 pack-year smoking history and multiple comorbidities, including COPD, presents to the emergency department with left-sided hemiparesis and sensory loss.

COPD Education Program Improved Patient Knowledge of Disease

COPD Education Program Improved Patient Knowledge of Disease

There was as significant change in Bristol COPD Knowledge Questionnaire scores in patients who received a brief education program at the time of an acute exacerbation of COPD.

Stroke, MI Risk Increased After Severe COPD Exacerbations

Stroke, MI Risk Increased After Severe COPD Exacerbations

Acute COPD exacerbations were associated with an increased risk for myocardial infarction and ischemic stroke.

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Zephyr® Endobronchial Valve EBV® treatment improved FEV1 in patients with heterogeneous emphysema.

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

The inclusion of residual volume-to-total lung capacity ratio may add another dimension to COPD not routinely captured by standard airflow indices that could be predictive of lower maximum exercise capacity.

COPD Triple Therapy Switch to LABA/LAMA May Be Appropriate in Some Patients

COPD Triple Therapy Switch to LABA/LAMA May Be Appropriate in Some Patients

A direct de-escalation from triple therapy to indacaterol/glycopyrronium may be appropriate in patients with infrequent COPD exacerbations.

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

A definition of a pulmonary vascular phenotype of chronic obstructive pulmonary disease has been proposed.

COPD and the "Obesity Paradox:" Is a Higher BMI Protective?

COPD and the "Obesity Paradox:" Is a Higher BMI Protective?

Recent research suggests that increasing obesity class is independently associated with worse respiratory-specific and general quality of life outcomes in COPD.

E-Cigarette Use Associated With Increased Risk for COPD

E-Cigarette Use Associated With Increased Risk for COPD

Using e-cigarettes every day or some days increased the likelihood of developing chronic obstructive pulmonary disease.

COPD Frequently Misdiagnosed, Undiagnosed in Individuals With or Without HIV

COPD Frequently Misdiagnosed, Undiagnosed in Individuals With or Without HIV

In this study, researchers examined the appropriateness of diagnosis and treatment of chronic obstructive pulmonary disease in individuals with and without HIV.

Mortality Rates in Extrafine ICS-Containing vs ICS-Free Medications in COPD

Mortality Rates in Extrafine ICS-Containing vs ICS-Free Medications in COPD

The pooled safety analysis included data from the TRILOGY, TRINITY, and TRIBUTE studies.

Incident Diuretic Use May Increase Adverse Events in COPD

Incident Diuretic Use May Increase Adverse Events in COPD

Incident diuretic use was associated with increased rates of respiratory-related morbidity and mortality in older adults with chronic obstructive pulmonary disease.

Assessing Depression Following Inpatient COPD Rehabilitation

Assessing Depression Following Inpatient COPD Rehabilitation

PHQ-9 and PHQ-2 show factorial validity, invariance, and reliability for measuring depression in patients with chronic obstructive pulmonary disease.

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative care consultation was linked to a reduction in hospital costs for hospitalized adults with serious illness, such as COPD.

Survival Predictors When Life Support Is Withheld in ICU

Survival Predictors When Life Support Is Withheld in ICU

Survival at 6 months was significantly associated with acute respiratory failure and history of COPD.

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

A higher proportion of patients with COPD and a blood eosinophil count of ≥0.34×109/L had elevated markers of low-grade systemic inflammation regardless of forced expiratory volume in 1 second.

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

Readmission rates were highest during the first 72 hours after admission for an acute exacerbation of chronic obstructive pulmonary disease.

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

Adding olodaterol to tiotropium did not significantly reduce exacerbations in patients with chronic obstructive pulmonary disease as much as researchers had anticipated.

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD overlap linked to higher prevalence of sleep-related symptoms, including difficulty falling asleep and maintaining sleep, early-morning awakening, and excessive daytime sleepiness.

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

The drug consists of fluticasone furoate, an inhaled corticosteroid (ICS), umeclidinium, a long-acting muscarinic antagonist, and vilanterol, a long-acting beta2-adrenergic agonist (LABA), delivered via an Ellipta dry powder inhaler.

Transcatheter vs Surgical Aortic Valve Replacement in COPD

Transcatheter vs Surgical Aortic Valve Replacement in COPD

In patients with COPD, transcatheter aortic valve replacement was associated with fewer respiratory-related complications than surgical aortic valve replacement.

Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple Therapy Tied to Reduced Rate of COPD Exacerbations

Triple therapy with fluticasone furoate, umeclidinium, and vilanterol was associated with a lower rate of exacerbations in chronic obstructive pulmonary disease.

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

COPD Risk in Middle-Age: The 3-Way Interaction of Asthma, Smoking, and Measles

A childhood measles infection may increase the risk for post-bronchodilator airflow obstruction in middle-age adults via its interaction with asthma and smoking.

Cardiovascular Complications of COPD

Cardiovascular Complications of COPD

A 55-year-old man with chronic obstructive pulmonary disease reports having some mild chest pain.

Perioperative Risk Assessment in a Patient With COPD

Perioperative Risk Assessment in a Patient With COPD

A 64-year-old man with chronic obstructive pulmonary disease, diabetes, chronic kidney disease, and morbid obesity seeks preoperative approval for femoral popliteal bypass surgery.

Fixed-Dosed Dual Bronchodilators for COPD: Overview and Clinician Interview

Fixed-Dosed Dual Bronchodilators for COPD: Overview and Clinician Interview

Treating chronic obstructive pulmonary disease remains challenging, particularly in terms of choosing the appropriate fixed-dose combination bronchodilator.

COPD Risk Predicted by Large Airway Dimensions on Computed Tomography

COPD Risk Predicted by Large Airway Dimensions on Computed Tomography

Greater Pi10 was associated with incident spirometry-defined chronic obstructive pulmonary disease in a general population-based sample without clinical lung disease.

Tai Chi Helps Improve Respiratory Function in COPD

Tai Chi Helps Improve Respiratory Function in COPD

Tai chi found to be as effective as pulmonary rehabilitation for patients with chronic obstructive pulmonary disease.

Debating Noninvasive vs Invasive Ventilation in Acute Exacerbations of COPD

Debating Noninvasive vs Invasive Ventilation in Acute Exacerbations of COPD

It is still not known whether differences in mortality rates between patients who receive noninvasive vs invasive ventilation for acute exacerbations of COPD can be attributed to less severe disease or other factors.

Distinct Lung Function Trajectories Associated With COPD Risk

Distinct Lung Function Trajectories Associated With COPD Risk

Researchers identified 6 distinct FEV1 lung function trajectories, 3 of which were responsible for 75% of the COPD burden.

Lonhala Magnair Now Available for Long-Term COPD Maintenance

Lonhala Magnair Now Available for Long-Term COPD Maintenance

Lonhala Magnair is available as a 25mcg strength inhalation solution per 1mL vial.

Simple Lung Function Tests in Primary Care Help ID Early COPD

Simple Lung Function Tests in Primary Care Help ID Early COPD

Peak flow meter, microspirometry are optimal, with full spirometry for positive results.

Sleep Quality in COPD May Predict Overall Quality of Life

Sleep Quality in COPD May Predict Overall Quality of Life

Sleep quality in patients with chronic obstructive pulmonary disease may be a significant predictor of multiple metrics of quality of life.

Two Inhalers Go Head-to-Head in COPD Exacerbation Study

Two Inhalers Go Head-to-Head in COPD Exacerbation Study

Study authors concluded, "Combining tiotropium and olodaterol did not reduce exacerbation rate as much as expected compared with tiotropium alone."

COPD: Disease Management Care vs Recommended Care Alone

COPD: Disease Management Care vs Recommended Care Alone

Disease management added to recommended care in chronic obstructive pulmonary disease was not superior to recommended care alone.

Efficacy of Different Doses of Glycopyrronium Via a Metered Dose Inhaler in COPD

Efficacy of Different Doses of Glycopyrronium Via a Metered Dose Inhaler in COPD

Four different doses of glycopyrronium delivered via metered dose inhaler were compared for safety and efficacy in the treatment of chronic obstructive pulmonary disease.

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Prevent Treatment Nonadherence in Asthma, COPD: Build Strong Patient Relationships

Patients with asthma or chronic obstructive pulmonary disease have especially high rates of nonadherence, even in comparison with other chronic diseases.

Specific COPD Questionnaire Cutoff Threshold May Identify More Symptomatic Patients

Specific COPD Questionnaire Cutoff Threshold May Identify More Symptomatic Patients

The Clinical COPD Questionnaire cutoff point of 1.4 demonstrated a better agreement with other COPD measures in patients with more symptomatic disease.

Emphysema Threshold on CT Imaging May Have Predictive Value for COPD

Emphysema Threshold on CT Imaging May Have Predictive Value for COPD

Patients with chronic obstructive pulmonary disease with 5% emphysema based on thoracic computed tomography (CT) imaging may be at a greater risk for poor outcomes.

COPD Combination Therapy May Improve Lung Hyperinflation

COPD Combination Therapy May Improve Lung Hyperinflation

Combination treatment with indacaterol-glycopyrronium may improve cardiac function in patients with chronic obstructive pulmonary disease.

COPD Mortality Risk and Physical Activity Have Dose-Response Relationship

COPD Mortality Risk and Physical Activity Have Dose-Response Relationship

Individuals with chronic obstructive pulmonary disease who met physical activity guidelines experienced the greatest reductions in all-cause, CVD, and respiratory mortality risk.

Glucocorticoids Do Not Increase Fracture Risk in COPD

Glucocorticoids Do Not Increase Fracture Risk in COPD

Intermittent use of high-dose glucocorticoids did not increase the risk for fracture in patients with COPD.

Lung Cancer Risk May Be Predicted by Frequency of COPD Exacerbations

Lung Cancer Risk May Be Predicted by Frequency of COPD Exacerbations

Independent predictive factors of lung cancer in chronic obstructive pulmonary disease may include frequency of exacerbations, in addition to airflow obstruction and visual emphysema.

COPD, Respiratory Symptoms Associated With "Western" Diet

COPD, Respiratory Symptoms Associated With "Western" Diet

Researchers used data from the Atherosclerosis Risk in Communities Study to assess associations between dietary pattern and pulmonary assessments.

Severe COPD Exacerbations, Hospitalizations Reduced With Azithromycin

Severe COPD Exacerbations, Hospitalizations Reduced With Azithromycin

Long-term continuous cyclic azithromycin therapy for severe chronic obstructive pulmonary disease was associated with reductions in exacerbations and hospitalizations.

COPD Prevalence, Hospitalizations, and Deaths in Rural Areas

COPD Prevalence, Hospitalizations, and Deaths in Rural Areas

Rural areas have a significantly higher prevalence of chronic obstructive pulmonary disease.

Extrafine Inhaled Triple Therapy vs Dual Bronchodilator Therapy for COPD

Extrafine Inhaled Triple Therapy vs Dual Bronchodilator Therapy for COPD

The TRIBUTE study was the first long-term trial that specifically compared the effects of the extrafine inhaled corticosteroid-containing triple therapy regimen of beclomethasone dipropionate, formoterol fumarate, and glycopyrronium with the dual bronchodilator combination of indacaterol plus glycopyrronium for COPD.

Concomitant Use of Beta-Blockers, Beta-Agonists in COPD With CV Risk

Concomitant Use of Beta-Blockers, Beta-Agonists in COPD With CV Risk

Patients with COPD and heightened cardiovascular risk received respiratory benefits from long-acting beta-agonist therapy without increasing their cardiovascular risk, regardless of beta-blocker therapy.

Predictors of Mortality After Hospitalization for COPD Exacerbation

Predictors of Mortality After Hospitalization for COPD Exacerbation

One-year mortality after the initial hospitalization for chronic obstructive pulmonary disease exacerbation was related to clinical characteristics of the patient and of the index event.

Long-Term Inhaled Corticosteroid Use in COPD May Increase Fracture Risk

Long-Term Inhaled Corticosteroid Use in COPD May Increase Fracture Risk

Patients with chronic obstructive pulmonary disease had a modest increased risk for hip and upper extremity fractures when taking long-term, high-dose inhaled corticosteroids.

COPD-Related Lung Transplantation: How Can We Improve Survival Rates?

COPD-Related Lung Transplantation: How Can We Improve Survival Rates?

Lung transplantation can improve survival in patients with chronic obstructive pulmonary disease, but several variables can affect the surgery's success.

Palliative Care for COPD: Physicians' Views and Treatment Patterns

Palliative Care for COPD: Physicians' Views and Treatment Patterns

Researchers conducted an anonymous survey of medical trainees with a case vignette to determine attitudes regarding palliative care for chronic obstructive pulmonary disease.

Antibiotics for Acute Exacerbations in COPD: Comparison of Effectiveness and Tolerability

Antibiotics for Acute Exacerbations in COPD: Comparison of Effectiveness and Tolerability

Researchers compared the clinical cure and adverse effect rates of multiple antibiotics in the treatment of acute exacerbations in chronic obstructive pulmonary disease.

Blood Biomarkers Add Value to COPD Mortality Predictive Model

Blood Biomarkers Add Value to COPD Mortality Predictive Model

High levels of C-reactive protein and neutrophils as well as low eosinophil count predicted a poor prognosis in COPD.

Respiratory Symptoms in Young Adults: Prognostic Value for Later Lung Function?

Respiratory Symptoms in Young Adults: Prognostic Value for Later Lung Function?

Respiratory symptoms that develop between the ages of 18 and 30 may hold prognostic value for later decline in lung function.

Guiding COPD Management Using Airway Branch Variation

Guiding COPD Management Using Airway Branch Variation

Researchers examined variation in airway branches to determine whether they have an effect on the course of chronic obstructive pulmonary disease.

COPD Exercise Capacity With Long-Acting Bronchodilators

COPD Exercise Capacity With Long-Acting Bronchodilators

Patients with COPD experienced a weighted mean increase in exercise endurance time following treatment with long-acting bronchodilators.

COPD Study Supports Concomitant Beta-Blocker Use in Moderate to Severe Disease

COPD Study Supports Concomitant Beta-Blocker Use in Moderate to Severe Disease

Lung function may not differ between individuals who take beta-blockers vs those who do not for moderate to severe chronic obstructive pulmonary disease.

Clinical Challenge: Elderly Man Presents With Dyspnea at Rest and Chronic Cough

Clinical Challenge: Elderly Man Presents With Dyspnea at Rest and Chronic Cough

An 80-year-old man with a history of smoking, hypertension, diabetes, and COPD presents to the emergency department with dyspnea at rest and chest tightness.

Predicting COPD Exacerbations, Treatment Responses via Eosinophil Counts

Predicting COPD Exacerbations, Treatment Responses via Eosinophil Counts

COPD exacerbation risk and treatment response may be predicted using blood eosinophil counts.

Procalcitonin-Guided Pneumonia Treatment Associated With Improved Outcomes

Procalcitonin-Guided Pneumonia Treatment Associated With Improved Outcomes

Procalcitonin may decrease mortality rates in patients with acute respiratory infections, including pneumonia.

COPD Mortality Predictions by GOLD 2017 vs Previous Versions

COPD Mortality Predictions by GOLD 2017 vs Previous Versions

Although the 2017 GOLD classification did not better predict mortality in patients with chronic obstructive pulmonary disease overall, it did so when patients were extensively categorized by severity.

COPD Continues to Present Screening Challenges, Research Barriers

COPD Continues to Present Screening Challenges, Research Barriers

No data have demonstrated improved mortality, morbidity, or quality of life as a result of screening for COPD in asymptomatic individuals.

Postoperative Pulmonary Complications With Asthma or COPD

Postoperative Pulmonary Complications With Asthma or COPD

Researchers found various risk factors for postoperative pulmonary complications in patients with either asthma or COPD.

Preventing COPD Exacerbations in Upper Respiratory Tract Infections

Preventing COPD Exacerbations in Upper Respiratory Tract Infections

A significant reduction in severe COPD exacerbations was seen with intensified combination therapy at the onset of upper respiratory tract infections.

COPD Home-Based Coaching Intervention: Effects on Physical Activity, Healthcare Utilization

COPD Home-Based Coaching Intervention: Effects on Physical Activity, Healthcare Utilization

Patients with COPD may increase their physical activity levels using a home-based coaching intervention.

Stable Hypercapnic COPD May Benefit From At-Home High-Flow Nasal Cannula Oxygen Therapy

Stable Hypercapnic COPD May Benefit From At-Home High-Flow Nasal Cannula Oxygen Therapy

Patients with stable hypercapnic COPD reported improved health-related quality of life after 6 weeks of at-home high-flow nasal cannula oxygen therapy.

Inhaled Long-Acting Bronchodilators for COPD: Potential Cardiovascular Risk

Inhaled Long-Acting Bronchodilators for COPD: Potential Cardiovascular Risk

Within the first 30 days of therapy, patients with COPD who began using long-acting bronchodilators had a 1.5-fold increased risk for cardiovascular events.

COPD and Asthma Risk in Women With Rheumatoid Arthritis

COPD and Asthma Risk in Women With Rheumatoid Arthritis

Women with rheumatoid arthritis had an increased risk for chronic obstructive pulmonary disease, but did not have an increased risk for asthma compared with women without RA.

Effect of Beta-Blockers on Hospitalization in COPD and Concurrent Heart Failure

Effect of Beta-Blockers on Hospitalization in COPD and Concurrent Heart Failure

Carvedilol may increase the risk for hospitalization in patients with concurrent heart failure and COPD compared with metoprolol/bisoprolol/nebivolol.

A Middle-Aged Man With Worsening COPD

A Middle-Aged Man With Worsening COPD

A middle-aged man diagnosed with COPD presents with shortness of breath at rest with no improvement with nebulizer treatments.

Progression of Emphysema With Regular Aspirin Use

Progression of Emphysema With Regular Aspirin Use

Regular use of aspirin may slow the progression of emphysema.

Nasal High-Flow Oxygen Corrects Hypoxemia, Reduces Hypercapnia in COPD

Nasal High-Flow Oxygen Corrects Hypoxemia, Reduces Hypercapnia in COPD

Nasal high-flow oxygen therapy may be a safe and effective therapy for patients with normocapnic and hypercapnic COPD.

Chronic Lung Disease Research in the Pipeline: An Interview With Augustine M.K. Choi, MD

Chronic Lung Disease Research in the Pipeline: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD, Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

Examining the Efficacy of Carbon Monoxide Therapy in Idiopathic Pulmonary Fibrosis: An Interview With Augustine M.K. Choi, MD

Examining the Efficacy of Carbon Monoxide Therapy in Idiopathic Pulmonary Fibrosis: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD, Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

Identifying New Therapeutics for Pulmonary Diseases: An Interview With Augustine M.K. Choi, MD

Identifying New Therapeutics for Pulmonary Diseases: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD of Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

Overview of Autophagy Research in COPD: An Interview With Augustine M.K. Choi, MD

Overview of Autophagy Research in COPD: An Interview With Augustine M.K. Choi, MD

Pulmonology Advisor sits down with Augustine M.K. Choi, MD, Stephen and Suzanne Weiss Dean of Weill Cornell Medicine to discuss the latest topics in pulmonary medicine.

FDA Approves First Nebulized Long-Acting Muscarinic Antagonist for COPD

FDA Approves First Nebulized Long-Acting Muscarinic Antagonist for COPD

Adults treated with Lonhala Magnair showed statistically significant and clinically important changes in FEV1 at week 12 vs placebo.

Walking in Polluted Area Blunts Cardiorespiratory Benefits

Walking in Polluted Area Blunts Cardiorespiratory Benefits

Concentrations of black carbon, nitrogen dioxide, and particulate matter were higher in traffic-polluted areas, and linked to more instances of cough, sputum, and shortness of breath.

Predicting COPD Exacerbations Using Sputum vs Blood Eosinophils

Predicting COPD Exacerbations Using Sputum vs Blood Eosinophils

Sputum eosinophil counts may be a better predictor of COPD exacerbations compared with serum blood eosinophil counts.

COPD Adverse Outcomes May Increase With Loop Diuretic Use

COPD Adverse Outcomes May Increase With Loop Diuretic Use

Older patients with COPD who use loop diuretics may be at an increased risk for respiratory-related morbidity and mortality.

Noninvasive Ventilation for Acute Hypercapnic Respiratory Failure Related to COPD

Noninvasive Ventilation for Acute Hypercapnic Respiratory Failure Related to COPD

Noninvasive ventilation may reduce mortality in patients with acute hypercapnic respiratory failure related to COPD.

COPD Hospitalization Outcomes Affected by Obesity

COPD Hospitalization Outcomes Affected by Obesity

Patients with obesity who are hospitalized for an acute exacerbation of COPD may have longer hospital stays and more often require mechanical ventilation.

Long-Term Inhaled Corticosteroid Use Associated With Increased Sputum Bacterial Load in COPD

Long-Term Inhaled Corticosteroid Use Associated With Increased Sputum Bacterial Load in COPD

Salmeterol plus fluticasone was associated with a significant increase in sputum bacterial load in chronic obstructive pulmonary disease, compared to salmeterol alone.

COPD Hospitalization Risk With Rheumatoid Arthritis

COPD Hospitalization Risk With Rheumatoid Arthritis

Rheumatoid arthritis increased the risk of COPD-related hospitalization by 47%.

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