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COPD and the "Obesity Paradox:" Is a Higher BMI Protective?

COPD and the "Obesity Paradox:" Is a Higher BMI Protective?

Recent research suggests that increasing obesity class is independently associated with worse respiratory-specific and general quality of life outcomes in COPD.

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Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Severe Emphysema Benefits From Zephyr® Endobronchial Valve Treatment

Zephyr® Endobronchial Valve EBV® treatment improved FEV1 in patients with heterogeneous emphysema.

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

COPD Risk From Secondhand Smoke May Be Linked With Lung Volume Variations

The inclusion of residual volume-to-total lung capacity ratio may add another dimension to COPD not routinely captured by standard airflow indices that could be predictive of lower maximum exercise capacity.

Triple Therapy Recommended for COPD With Infrequent Exacerbations

Triple Therapy Recommended for COPD With Infrequent Exacerbations

A direct de-escalation from triple therapy to indacaterol/glycopyrronium is not recommended over triple therapy in COPD with infrequent exacerbations.

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

Potential COPD Pulmonary Vascular Phenotype Associated With Poor Outcomes

A definition of a pulmonary vascular phenotype of chronic obstructive pulmonary disease has been proposed.

COPD and the "Obesity Paradox:" Is a Higher BMI Protective?

COPD and the "Obesity Paradox:" Is a Higher BMI Protective?

Recent research suggests that increasing obesity class is independently associated with worse respiratory-specific and general quality of life outcomes in COPD.

E-Cigarette Use Associated With Increased Risk for COPD

E-Cigarette Use Associated With Increased Risk for COPD

Using e-cigarettes every day or some days increased the likelihood of developing chronic obstructive pulmonary disease.

COPD Frequently Misdiagnosed, Undiagnosed in Individuals With or Without HIV

COPD Frequently Misdiagnosed, Undiagnosed in Individuals With or Without HIV

In this study, researchers examined the appropriateness of diagnosis and treatment of chronic obstructive pulmonary disease in individuals with and without HIV.

Mortality Rates in Extrafine ICS-Containing vs ICS-Free Medications in COPD

Mortality Rates in Extrafine ICS-Containing vs ICS-Free Medications in COPD

The pooled safety analysis included data from the TRILOGY, TRINITY, and TRIBUTE studies.

Incident Diuretic Use May Increase Adverse Events in COPD

Incident Diuretic Use May Increase Adverse Events in COPD

Incident diuretic use was associated with increased rates of respiratory-related morbidity and mortality in older adults with chronic obstructive pulmonary disease.

Assessing Depression Following Inpatient COPD Rehabilitation

Assessing Depression Following Inpatient COPD Rehabilitation

PHQ-9 and PHQ-2 show factorial validity, invariance, and reliability for measuring depression in patients with chronic obstructive pulmonary disease.

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

COPD, Asthma, or Asthma COPD Overlap Syndrome: Diagnostic Challenges

Emerging guidelines for diagnosing and treating asthma COPD overlap syndrome will help clinicians better manage patients and prevent serious adverse effects.

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative care consultation was linked to a reduction in hospital costs for hospitalized adults with serious illness, such as COPD.

Survival Predictors When Life Support Is Withheld in ICU

Survival Predictors When Life Support Is Withheld in ICU

Survival at 6 months was significantly associated with acute respiratory failure and history of COPD.

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

Pneumonia Risk in Severe COPD Linked to Elevated Eosinophil Count

A higher proportion of patients with COPD and a blood eosinophil count of ≥0.34×109/L had elevated markers of low-grade systemic inflammation regardless of forced expiratory volume in 1 second.

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

Early Readmission Factors in COPD After Hospitalization for Acute Exacerbation

Readmission rates were highest during the first 72 hours after admission for an acute exacerbation of chronic obstructive pulmonary disease.

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

Addition of Olodaterol to Tiotropium Does Not Significantly Reduce COPD Exacerbations

Adding olodaterol to tiotropium did not significantly reduce exacerbations in patients with chronic obstructive pulmonary disease as much as researchers had anticipated.

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD Overlap Associated With Higher Risk for Sleep-Related Symptoms

Asthma and COPD overlap linked to higher prevalence of sleep-related symptoms, including difficulty falling asleep and maintaining sleep, early-morning awakening, and excessive daytime sleepiness.

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

Trelegy Ellipta Gains Expanded COPD Indication, Loses Boxed Warning

The drug consists of fluticasone furoate, an inhaled corticosteroid (ICS), umeclidinium, a long-acting muscarinic antagonist, and vilanterol, a long-acting beta2-adrenergic agonist (LABA), delivered via an Ellipta dry powder inhaler.

Transcatheter vs Surgical Aortic Valve Replacement in COPD

Transcatheter vs Surgical Aortic Valve Replacement in COPD

In patients with COPD, transcatheter aortic valve replacement was associated with fewer respiratory-related complications than surgical aortic valve replacement.

Breathing New Life Into COPD and Asthma Therapy With Statins

Breathing New Life Into COPD and Asthma Therapy With Statins

Statins have anti-inflammatory and anti-oxidative effects, which could reduce exacerbations of both asthma and chronic obstructive pulmonary disease.

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