Critical Care

Use of Predicted vs Measured Body Weight for Targeting Tidal Volumes in Children

Use of Predicted vs Measured Body Weight for Targeting Tidal Volumes in Children

By

It may be more lung protective to use the lower of either measured or predicted body weight when targeting tidal volume for mechanically ventilated children.

Does Propofol Prevent Prolonged Desaturation During Neonatal Intubation?

Does Propofol Prevent Prolonged Desaturation During Neonatal Intubation?

By

A randomized clinical trial evaluated whether premedication with propofol reduced the frequency of prolonged desaturation during neonatal nasotracheal intubation compared with the combination of a rapid-onset short-acting opioid and a muscle relaxant.

Molecular Laboratory Test Can Discriminate Sepsis From Noninfectious SIRS

Molecular Laboratory Test Can Discriminate Sepsis From Noninfectious SIRS

The SeptiCyteTM LAB may be an effective complementary diagnostic tool to clinical assessment of critically ill adult patients in discriminating between sepsis and noninfectious systemic inflammation syndrome.

Talc Via Pleural Catheter vs Indwelling Pleural Catheter Alone for Pleurodesis

Talc Via Pleural Catheter vs Indwelling Pleural Catheter Alone for Pleurodesis

By

An indwelling pleural catheter and administration of talc may have a higher odds of achieving pleurodesis compared with an indwelling pleural catheter alone in individuals with malignant pleural effusions.

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative Care Consult Can Cut Hospital Costs in Seriously Ill

Palliative care consultation was linked to a reduction in hospital costs for hospitalized adults with serious illness, such as COPD.

Survival Predictors When Life Support Is Withheld in ICU

Survival Predictors When Life Support Is Withheld in ICU

By

Survival at 6 months was significantly associated with acute respiratory failure and history of COPD.

Balanced crystalloids decreases adverse kidney events compared to saline among critically ill patients: The SMART trial

Use of balanced crystalloids (lactated Ringers or Plasma-Lyte A) was associated with a significant reduction in acute kidney injury events compared with normal saline among intensive care unit (ICU) patients. Use of balanced crystalloids was also associated with lower though nonsignificant in-hospital mortality at 30-days after admission.

Insulin-Treated Diabetes Reduces Dysglycemia-Related Mortality in Sepsis

Insulin-Treated Diabetes Reduces Dysglycemia-Related Mortality in Sepsis

By

In patients with insulin-treated diabetes and sepsis, increased highest glucose levels and glycemic variability have a significant illness severity-adjusted association with decreasing in-hospital mortality.

Mortality in Mechanically Ventilated Community-Acquired Pneumonia With or Without ARDS

Mortality in Mechanically Ventilated Community-Acquired Pneumonia With or Without ARDS

By

The risk for death in patients with community-acquired pneumonia who were given mechanical ventilation does not seem to be affected by the presence of acute respiratory distress syndrome.

Specific Delirium Phenotypes May Predict Long-Term Cognitive Impairment

Specific Delirium Phenotypes May Predict Long-Term Cognitive Impairment

By

Sedative-associated, hypoxic, and septic delirium were predictive of long-term cognitive impairment in patients with a critical illness related to acute respiratory failure, shock, or both.

Delirium in ICU Prevented With Nocturnal Administration of Dexmedetomidine

Delirium in ICU Prevented With Nocturnal Administration of Dexmedetomidine

By

A higher percentage of critically ill patients in the intensive care unit who were given nocturnal dexmedetomidine remained delirium free compared with placebo.

High-Flow vs Standard Oxygen Therapy in Infants With Bronchiolitis

High-Flow vs Standard Oxygen Therapy in Infants With Bronchiolitis

High-flow oxygen therapy may be more effective in preventing care escalation in infants with bronchiolitis compared with standard oxygen therapy.

Prophylactic haloperidol not linked to improved survival in ICU patients: The REDUCE trial

Prophylactic haloperidol did not reduce delirium incidence, delirium-free days, duration of mechanical ventilation, or hospital length of stay in patients in the intensive care unit.

Adjunctive glucocorticoid therapy does not lower mortality in septic shock

Patients with septic shock in the intensive care unit undergoing mechanical ventilation and managed with adjunctive continuous hydrocortisone infusion did not have a lower 90-day mortality compared with placebo.

Routine Chest Radiography After US-Guided CVC Insertion Often Unnecessary

Routine Chest Radiography After US-Guided CVC Insertion Often Unnecessary

By

A routine chest radiograph after ultrasound-guided central venous catheter insertion is now considered costly and unnecessary.

Ventilator-Free Days in ICU With On-Demand vs Routine Nebulization

Ventilator-Free Days in ICU With On-Demand vs Routine Nebulization

By

On-demand nebulization of acetylcysteine with salbutamol did not result in an inferior number of ventilator-free days compared with routine nebulization.

Revisit to ED May Indicate Poor Outcomes in Elderly Patients

Revisit to ED May Indicate Poor Outcomes in Elderly Patients

A revisit to the emergency department within 30 days of a previous visit predicted poor outcomes in elderly adults.

Airway Management Methods During ACLS: Jury Still Out

Airway Management Methods During ACLS: Jury Still Out

By

A study sought to determine whether bag-mask ventilation was noninferior to endotracheal intubation as initial airway management during advanced cardiac life support during out-of-hospital cardiac arrest.

Effect of Haloperidol in Critically Ill Patients at Risk for Delirium

Effect of Haloperidol in Critically Ill Patients at Risk for Delirium

Prophylactic haloperidol does not improve survival at 28 days compared with placebo in critically ill adults

Effects of Lowering PEEP Below Recommended Values in Pediatric ARDS

Effects of Lowering PEEP Below Recommended Values in Pediatric ARDS

By

An overall higher mortality rate was associated with pediatric acute respiratory distress syndrome ARDS management with PEEP levels lower than those recommended by the ARDS Network PEEP/FiO2 protocol.

Neonates With Respiratory Distress Syndrome: Does Inhaled Nitric Oxide Reduce Mortality?

Neonates With Respiratory Distress Syndrome: Does Inhaled Nitric Oxide Reduce Mortality?

Off-label use of inhaled nitric oxide is not associated with reduced mortality in neonates born at 22 to 29 weeks'gestation with RDS.

Palliative Care for COPD: Physicians' Views and Treatment Patterns

Palliative Care for COPD: Physicians' Views and Treatment Patterns

By

Researchers conducted an anonymous survey of medical trainees with a case vignette to determine attitudes regarding palliative care for chronic obstructive pulmonary disease.

Invasive Mechanical Ventilation in Severe CAP Increased Mortality Risk

Invasive Mechanical Ventilation in Severe CAP Increased Mortality Risk

By

Invasive mechanical ventilation in patients with severe community-acquired pneumonia appeared to increase their mortality risk.

Enteral vs Parenteral Nutrition in Critical Care Requiring Mechanical Ventilation

Enteral vs Parenteral Nutrition in Critical Care Requiring Mechanical Ventilation

By

Enteral nutritional support was not clinically superior to parenteral nutritional support in critically ill patients receiving mechanical ventilation.

Examining Compression-to-Ventilation Ratios for Optimal Neurologic, Survival Outcomes

Examining Compression-to-Ventilation Ratios for Optimal Neurologic, Survival Outcomes

By

Adults with cardiac arrest have better outcomes with continuous compressions with asynchronous ventilations or compression-to-ventilation ratios of 30:2.

Lung Recruitment Maneuver With Titrated PEEP Increases Mortality in Moderate to Severe ARDS

Lung Recruitment Maneuver With Titrated PEEP Increases Mortality in Moderate to Severe ARDS

By

A randomized trial sought to determine whether the use of titrated positive end-expiratory pressure influenced the 28-day mortality risk in patients with acute respiratory distress syndrome.

Low Tidal Volume Strategy in Acute Respiratory Distress Syndrome

Low Tidal Volume Strategy in Acute Respiratory Distress Syndrome

By

A low tidal volume ventilation strategy in patients with acute respiratory distress syndrome demonstrated a trend toward improved mortality.

Extended VTE Pharmacologic Thromboprophylaxis Is Safe After Liver Surgery

Extended VTE Pharmacologic Thromboprophylaxis Is Safe After Liver Surgery

Extended pharmacologic thromboprophylaxis seems to be safe and effective for patients getting liver surgery.

Transesophageal Echocardiography Training for Critical Care Fellows

Transesophageal Echocardiography Training for Critical Care Fellows

By

Transesophageal echocardiography can be used safely and effectively by critical care fellows to assess and manage cardiopulmonary failure when transthoracic echocardiography fails to provide adequate views.

Early Simvastatin Tx Does Not Decrease Delirium Duration in Criticall Ill Patients

Early Simvastatin Tx Does Not Decrease Delirium Duration in Criticall Ill Patients

By

Incidence of delirium and coma were not prevented with early initiation of simvastatin in patients on mechanical ventilation.

Sign Up for Free e-newsletters