Obesity:
Indications for ADIPEX-P:
Short-term monotherapy as adjunct in management of exogenous obesity in patients with initial body mass ≥30kg/m2, or ≥27kg/m2 in presence of other risk factors.
Adult Dosage:
>16yrs: 37.5mg once daily before or 1–2 hrs after breakfast, or 18.75mg 1–2 times daily. Avoid late evening dosing.
Children Dosage:
≤16yrs: not recommended.
ADIPEX-P Contraindications:
Arteriosclerosis. Cardiovascular disease. Hypertension. Hyperthyroidism. Glaucoma. Agitation. Drug or alcohol abuse. During or within 14 days of MAOIs.
ADIPEX-P Warnings/Precautions:
Discontinue if dyspnea, angina pectoris, syncope, lower extremity edema or other symptoms of primary pulmonary hypertension occur. Discontinue after a few weeks as tolerance to anorectic effect occurs. Diabetes. Prescribe limited supply to prevent overdose. Pregnancy (Cat.C). Nursing mothers: not recommended.
ADIPEX-P Classification:
Sympathomimetic.
ADIPEX-P Interactions:
Hypertensive crisis with MAOIs. Concomitant SSRIs: not recommended. Avoid alcohol. Blocks guanethidine. Monitor antidiabetic agents. Possible risk of valvular heart disease with fenfluramine.
Adverse Reactions:
CNS overstimulation, dizziness, palpitations, arrhythmias, hypertension, psychosis, dry mouth, GI disturbances, urticaria, impotence, primary pulmonary hypertension, and/or regurgitant cardiac valvular disease.
Generic Drug Availability:
YES
How Supplied:
Caps—100; Tabs—100, 1000
