Indications for APTENSIO XR:
Attention deficit hyperactivity disorder.
Limitations of Use:
Pediatrics <6yrs: experienced higher rates of adverse reactions (esp. weight loss).
Adults and Children:
Individualize. Swallow whole or may open capsule and sprinkle contents onto applesauce. <6yrs: not established. ≥6yrs: 10mg once daily in the AM. May titrate dose in weekly increments of 10mg/day. Max 60mg/day. Discontinue if no improvement after dose adjustment over a 1-month period.
APTENSIO XR Contraindications:
During or within 14 days of MAOIs.
Abuse and dependence.
APTENSIO XR Warnings/Precautions:
High potential for abuse and dependence; monitor. Increased risk of sudden death, stroke, and MI; assess for presence of cardiac disease before initiating. Avoid in known structural cardiac abnormalities, cardiomyopathy, serious arrhythmias, coronary artery disease, and other cardiac problems. Pre-existing psychotic disorder. Bipolar disorder. Screen for risk factors of developing a manic episode prior to initiation. Consider discontinuing if new psychotic/manic symptoms occur. Peripheral vasculopathy including Raynaud's phenomenon; monitor for digital changes. Monitor growth (in children), BP, HR. Reduce dose or discontinue if paradoxical aggravation of symptoms occurs. Write ℞ for smallest practical amount. Reevaluate periodically. Pregnancy. Nursing mothers: monitor infants.
APTENSIO XR Classification:
APTENSIO XR Interactions:
See Contraindications. Hypertensive crisis with concomitant MAOIs. Risk of serotonin syndrome with serotonergic drugs.
Headache, insomnia, abdominal pain, decreased appetite, nausea, vomiting, dizziness; hypertension, tachycardia, priapism.