Anesthetics:

Indications for: BYFAVO

Induction and maintenance of procedural sedation lasting 30mins or less.

Adult Dosage:

Individualize. Titrate to achieve clinical response. Give by IV inj. Induction: 5mg over 1min; for American Society of Anesthesiologists Physical Status (ASA-PS) III or IV: 2.5–5mg over 1min. Maintenance (as needed): 2.5mg over 15secs; for ASA-PS III or IV: 1.25–2.5mg over 15secs. Must wait ≥2mins prior to administration of any supplemental dose.

Children Dosage:

<18yrs: not established.

Boxed Warning:

Personnel and equipment for monitoring and resuscitation. Risks from concomitant use with opioid analgesics and other sedative-hypnotics.

BYFAVO Warnings/Precautions:

Should be administered only by trained personnel in procedural sedation, detection/management of airway obstruction, hypoventilation, and apnea. Have resuscitative drugs/equipment, supportive ventilation, reversal agent (eg, flumazenil) readily available. Give supplemental oxygen through the recovery period. Continuously monitor for cardiorespiratory effects (esp. in those with obstructive sleep apnea, elderly, ASA-PS III or IV patients). Neonatal sedation: monitor newborns. Pediatric neurotoxicity. Severe hepatic impairment. Elderly. Pregnancy. Labor & delivery. Nursing mothers: monitor infants; consider interrupting breastfeeding, pumping and discarding breast milk during and for 5hrs after administration.

BYFAVO Classification:

Benzodiazepine.

BYFAVO Interactions:

Increased risk of profound sedation, respiratory depression, coma, and death with concomitant CNS depressants, including opioid analgesics, other benzodiazepines, propofol; monitor continuously during and through recovery period; titrate Byfavo when concomitant with opioid analgesics and sedative-hypnotics.

Adverse Reactions:

Hypotension, hypertension, diastolic hyper- or hypotension, systolic hypertension, hypoxia; hypersensitivity reactions.

Generic Drug Availability:

NO

How Supplied:

Single-patient-use vial (12mL)—10

Pricing for BYFAVO

10 vials of 20mg carton (Qty: 1)
Appx. price $407
GoodRx