Actinic keratoses:
Indications for EFUDEX CREAM:
Multiple actinic or solar keratoses. Superficial basal cell carcinoma when conventional therapy is impractical (5% only); see literature.
Adult Dosage:
Keratoses: Apply twice daily until erosion occurs (usually 2–4 wks). Basal cell carcinoma (5% only): Apply twice daily, usually for 3–6 weeks (obliteration may take 10–12 weeks).
Children Dosage:
Not recommended.
EFUDEX CREAM Contraindications:
Dihydropyrimidine dehydrogenase (DPD) deficiency. Pregnancy (Cat.X).
EFUDEX CREAM Warnings/Precautions:
Apply cautiously near eyes, nose, mouth. Avoid mucous membranes, occlusion, ulcerated/inflamed skin, exposure to UV light. Wash hands after application if fingers were used. Notify patients of expected skin reaction. Biopsy unresponsive lesions. Nursing mothers: not recommended.
See Also:
EFUDEX CREAM Classification:
Antimetabolite.
Adverse Reactions:
Pain or burning at application site, pruritus, irritation, hyperpigmentation.
How Supplied:
Soln—10mL (w. drop dispenser); Crm—25g
Melanoma and other skin cancers:
Indications for EFUDEX CREAM:
Multiple actinic or solar keratoses. Superficial basal cell carcinoma when conventional therapy is impractical (5% only); see literature.
Adult Dosage:
Keratoses: Apply twice daily until erosion occurs (usually 2–4 wks). Basal cell carcinoma (5% only): Apply twice daily, usually for 3–6 weeks (obliteration may take 10–12 weeks).
Children Dosage:
Not recommended.
EFUDEX CREAM Contraindications:
Dihydropyrimidine dehydrogenase (DPD) deficiency. Pregnancy (Cat.X).
EFUDEX CREAM Warnings/Precautions:
Apply cautiously near eyes, nose, mouth. Avoid mucous membranes, occlusion, ulcerated/inflamed skin, exposure to UV light. Wash hands after application if fingers were used. Notify patients of expected skin reaction. Biopsy unresponsive lesions. Nursing mothers: not recommended.
See Also:
EFUDEX CREAM Classification:
Antimetabolite.
Adverse Reactions:
Pain or burning at application site, pruritus, irritation, hyperpigmentation.
How Supplied:
Soln—10mL (w. drop dispenser); Crm—25g
