Angina:

Indications for ISORDIL TITRADOSE:

Prophylaxis of angina. Not for acute attacks.

Adult Dosage:

Initially 5–20mg 2–3 times per day. Maintenance: 10–40mg 2–3 times per day; allow a daily dose-free interval of at least 14hrs.

Children Dosage:

Not established.

ISORDIL TITRADOSE Contraindications:

Concomitant PDEIs (eg, sildenafil, tadalafil, vardenafil), riociguat.

ISORDIL TITRADOSE Warnings/Precautions:

Recent MI. CHF. Hypotension. Volume depletion. Hypertrophic cardiomyopathy. Tolerance may develop. Elderly. Pregnancy (Cat.C). Nursing mothers.

ISORDIL TITRADOSE Classification:

Nitrate.

ISORDIL TITRADOSE Interactions:

See Contraindications. Severe hypotension with sildenafil. Hypotension potentiated with alcohol, other vasodilators, calcium channel blockers.

Adverse Reactions:

Headache, orthostatic hypotension, paradoxical bradycardia.

Note:

Sublingual tabs formerly known under the brand names Isordil, Sorbitrate.

Generic Drug Availability:

Titradose (YES)

How Supplied:

Sublingual—contact supplier; Titradose—100