Indications for RAGWITEK:

Short ragweed pollen-induced allergic rhinitis, with or without conjunctivitis, confirmed by (+) skin test or in vitro testing for pollen-specific IgE antibodies. Not for immediate relief of allergic symptoms.

Adult Dosage:

Initiate at least 12 weeks before onset of ragweed pollen season and continue throughout the season. Give 1st dose under physician supervision; observe ≥30 mins for any signs/symptoms of severe allergic reaction; if tolerated, subsequent doses may be taken at home. 18–65yrs: 1 tab daily. Allow complete dissolution under the tongue before swallowing. Avoid food or beverage for 5 mins after dosing.

Children Dosage:

<18yrs: not established.

RAGWITEK Contraindications:

Severe, unstable, or uncontrolled asthma. History of any severe systemic or local allergic reaction. History of eosinophilic esophagitis.

Boxed Warning:

Severe allergic reactions.

RAGWITEK Warnings/Precautions:

Risk of severe allergic reactions (eg, anaphylaxis, laryngopharyngeal restriction); discontinue if occurs. Prescribe auto-injectable epinephrine for emergency use. Underlying conditions that may reduce survival of a serious allergic reaction after epinephrine use (eg, markedly compromised lung function, unstable angina, recent MI, significant arrhythmia, uncontrolled HTN). Moderate or severe asthma. Withhold therapy in acute asthma exacerbation; consider discontinuing if recurrent. Interrupt therapy for oral inflammation or wounds to allow complete healing. Elderly (>65yrs). Pregnancy (Cat.C). Nursing mothers.

RAGWITEK Classification:

Allergen extract.

RAGWITEK Interactions:

Concomitant other allergen immunotherapy: not studied; may increase risk of local or systemic adverse reactions. Avoid concomitant drugs that can potentiate or inhibit effects of epinephrine (eg, beta-adrenergic blockers, alpha-adrenergic blockers, ergot alkaloids, TCAs, levothyroxine, MAOIs, chlorpheniramine, diphenhydramine, [cardiac glycosides, diuretics; monitor for arrhythmias]).

Adverse Reactions:

Throat irritation, pruritus (oral, ear, tongue), oral paresthesia, mouth edema; severe systemic or local allergic reactions, eosinophilic esophagitis (discontinue if occurs).

Generic Drug Availability:


How Supplied:

Blisters—30, 90

Pricing for RAGWITEK

30 sublingual tablets of 12 Amb a 1-U dose pack (Qty: 1)
Appx. price $344