Ocular infections:
Indications for VITRASERT:
Treatment of cytomegalovirus (CMV) retinitis in patients with AIDS.
Adults and Children:
<9yrs: not recommended. ≥9yrs: Implant designed to release drug over 5–8 months. May be removed and replaced following depletion of ganciclovir.
Contraindications:
External infection. Severe thrombocytopenia.
Warnings/Precautions:
Should be administered by surgeon who has observed or assisted in surgical implantation of Vitrasert prior to attempting procedure. Monitor for extraocular CMV disease. Ophthalmologic follow-up advised at appropriate intervals. Pregnancy (Cat.C). Nursing mothers: not recommended.
Pharmacologic Class:
Nucleoside analogue.
Adverse Reactions:
Visual acuity loss of 3 lines or more, vitreous hemorrhage, retinal detachments, cataract formation/lens opacities, macular abnormalities, intraocular pressure spikes, optic disk/nerve changes, hyphemas, uveitis.
How Supplied:
Implant—1
