Preliminary Diagnosis: Hepatomegaly
I. What imaging technique is first-line for this diagnosis
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Ultrasound with measurement of the liver in the longitudinal plane.
II. Describe the advantages and disadvantages of this technique for diagnosis of hepatomegaly.
Advantages
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Quick, inexpensive
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No ionizing radiation
Disadvantages
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Operator dependent to obtain accurate longitudinal measurements of the liver
III. What are the contraindications for the first-line imaging technique?
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No significant contraindications
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IV. What alternative imaging techniques are available?
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Plain Films
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CT
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MRI
V. Describe the advantages and disadvantages of the alternative techniques for diagnosis of hepatomegaly.
Plain film (radiographs)
Advantages
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Quick, inexpensive
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Minimal radiation exposure
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Can assess for displacement of right kidney and hepatic flexure
Disadvantages
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Limited in patients with large body habitus or significant intraluminal contrast or gas-filled prominent loops of bowel overlying the right upper quadrant
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Plain films are not very specific and lack very clear anatomic detail
CT
Advantages
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Can obtain imaging very quickly
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Able to visualize the liver in multiple planes; may be able to use 3-D reconstruction
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Very specific and helpful in identifying any possible lesions/masses/nodules within the liver if intravenous contrast administered
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Although greater exposure to radiation, triple phase CT is often very informative with all liver lesions as it provides comprehensive enhancement characteristic analysis
Disadvantages
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Greater exposure to ionizing radiation than plain film radiography
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More expensive than obtaining a radiograph, ultrasound, or palpation of the liver
MRI
Advantages
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Able to better visualize the liver in multiple planes
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Very specific and helpful to identify any possible lesions/masses/nodules within the liver especially if intravenous contrast is administered
Disadvantages
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More expensive than obtaining a CT, radiograph, ultrasound, or palpation of the liver
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Requires significant patient cooperation during acquisition of the images to minimize artifact
VI. What are the contraindications for the alternative imaging techniques?
Plain films (radiographs)
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No significant contraindications
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Relative contraindication in pregnancy
CT
Pregnancy
MRI
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Absolute contraindication in patients with non-MR compatible hardware
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