AAAAI: Egg Oral Immunotherapy Shows Sustained Benefit in Children
Egg-allergic children who undergo egg oral immunotherapy and achieve sustained unresponsiveness eat more egg and have fewer symptoms five years later.
AAAAI 2019
AAAAI 2019
Novel Peptide-Based Immunotherapy Holds Promise for Peanut Allergy
Basophil assays confirmed a lack of basophil reactivity to PVX108 vs peanut extract.
PPI Plus 4-Food Elimination Diet vs PPI Only in Eosinophilic Esophagitis
A 4-food elimination diet plus proton pump inhibitor therapy was more effective than PPI therapy alone in children with eosinophilic esophagitis.
Peanut Allergy Screening May Be Appropriate in Eosinophilic Esophagitis
Patients with eosinophilic esophagitis may have concurrent peanut allergy.
Children With Obesity Have Lower Immune Response to Vaccinations
The immune response to vaccinations is lower in children who are obese compared with nonobese children.
SABA Reduction Program Helped More Patients Achieve Ideal Asthma Medication Ratio Goal
The implementation of a short acting beta-agonist reduction program was associated with more patients fulfilling an asthma medication ratio ≥0.5.
Peanut Oral Immunotherapy Side Effects, Including Anaphylaxis, Common
Although peanut oral immunotherapy may be safe and effective in most patients with peanut allergies, mild gastrointestinal and cutaneous symptoms were common and anaphylaxis occurred in build-up and maintenance stages.
Asthma Associated With Osteoporosis, Other Bone Diseases
Asthma is linked to osteopenia, osteoporosis, osteomalacia, and pathological fractures in the United States.
Does Montelukast Increase the Risk for Neuropsychiatric Disease?
Children with asthma who received montelukast had no increased risk for neuropsychiatric disease compared with children who did not receive montelukast.
Accidental Exposure to Peanut Reported Less Often With AR101 Treatment
Patients who were actively treated with AR101 reported accidental exposure to peanut less often, had fewer associated adverse events, and required less rescue medication compared with placebo.
Quality of Sleep in Allergic Rhinitis Improved With House Dust Mite SLIT Tablet
Quality of sleep significantly improved in patients with allergic rhinitis who were treated with the house dust mite sublingual immunotherapy tablet.
Anti-Allergy Drug Need Associated With Use of Gastric Suppression Agents
People who take gastric acid suppression agents have a high risk of requiring subsequent anti-allergy drugs.
Allergy Associated With Mental Health Disorders in Pregnant Women
Eczema, rhinitis, and asthma were associated with an increased risk for depression in pregnant women.
Asthma Control in Morbidly Obese Children
Well-controlled asthma is possible in children with morbid obesity with participation in the Breathmobile program.
Peanut Food Equivalents May Safely Maintain Desensitization After Immunotherapy
Peanut food equivalents may be a safe option for maintaining desensitization after immunotherapy.
NSAID Allergy May Increase Risk for Opioid Use Disorder
Patients with low back pain or osteoarthritis who reported adverse drug reactions to nonsteroidal anti-inflammatory drugs have significantly higher odds of receiving prescriptions for opioids and developing opioid use disorder.
Dupilumab Effective, Safe in Chronic Rhinosinusitis With Nasal Polyps
Patients with chronic rhinosinusitis with nasal polyps experienced improvements in endoscopic, radiologic, and clinical outcomes when treated with dupilumab as add-on therapy to intranasal mometasone furoate.
Asthma Control, Quality of Life Improvements With Reslizumab
Treatment with reslizumab has been associated with clinically meaningful improvements in asthma control and quality of life.
Dupilumab Improves QoL in Uncontrolled Asthma and Allergic Rhinitis
Dupilumab improves health-related quality of life associated with rhinoconjunctivitis in patients with uncontrolled moderate to severe asthma with comorbid allergic rhinitis.
Severe Reaction Rates Increasing in Young Patients With Peanut Allergy
The comorbidity burden in young patients with peanut allergy is high, along with severe reaction rates and frequency of emergency room visits.
Gestational and Delivery Variables Linked With Dermatitis, Food Allergy Profiles
Gestational duration and Cesarean sections were associated with comorbid atopic dermatitis and food allergies in children, respectively.
Long-Term Effects of Macrolides in Children With Wheezing
The use of macrolide adjunctive therapy has been shown to be safe and effective for the treatment of children with wheezing disease.
Mepolizumab Improves QoL in Comorbid Asthma and Upper Airway Disease
Mepolizumab was associated with improvements in asthma control, quality of life and reductions in exacerbations in patients with comorbid severe asthma and upper airway disease.
Improving FEV1 in Children With Asthma: Tiotropium Add-On to ICS vs LTRAs
Tiotropium may be superior to leukotriene receptor antagonists as add-on therapy to an inhaled corticosteroid for improving forced expiratory volume in children with asthma.
Boiled Peanut OIT Provides Sustained Desensitization in Peanut Allergy
Boiled peanut oral immunotherapy effectively induced sustained unresponsiveness in children with peanut allergy.
Recurrent Wheeze Risk Linked With Prenatal Exposure to Acid Suppressants
Prenatal exposure to acid suppressant medication in infants diagnosed with severe bronchiolitis may increase the risk of developing recurrent wheeze.
Elevated Testosterone Associated With Decreased Likelihood of Asthma
Regardless of gender, patients with elevated serum testosterone levels were less likely to have current asthma.
Non-Allergic Rhinitis Symptoms Improved With Capsaicin
Patients with non-allergic rhinitis who received capsaicin exhibited rapid relief of symptoms compared with placebo.
GSP301 Improves Ocular Symptoms in Seasonal Allergic Rhinitis
GSP301 offers a rapid onset of action, is well tolerated, and is associated with improvements in ocular symptoms in patients with seasonal allergic rhinitis.
Lanadelumab Does Not Increase Cardiovascular Risk in Hereditary Angioedema
Patients with hereditary angioedema did not demonstrate higher cardiovascular risk when treated with lanadelumab compared with placebo.
AAAAI Annual Meeting 2019: What to Expect
A first look at what will be presented at the 2019 American Academy of Allergy, Asthma & Immunology annual meeting.
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