Peanut Allergy Screening May Be Appropriate in Eosinophilic Esophagitis

Patients with eosinophilic esophagitis may have concurrent peanut allergy.

This article is part of Pulmonology Advisor‘s coverage of the American Academy of Allergy, Asthma & Immunology annual meeting, taking place in San Francisco, California. Our staff will report on medical research related to asthma, allergy, and other respiratory conditions, conducted by experts in the field. Check back regularly for more news from AAAAI 2019.

SAN FRANCISCO — Patients with eosinophilic esophagitis (EoE) should be screened for peanut allergy, according to findings of a retrospective review presented at the annual meeting of the American Academy of Allergy, Asthma & Immunology held February 22-25 in San Francisco.

Researchers identified 519 patients diagnosed with EoE from the Eosinophilic Gastrointestinal Disorders Clinic at Texas Children’s Hospital in Houston. The ages of the patients ranged from 1 to 31 years, and peanut allergy was confirmed from positive specific peanut immunoglobulin E and/or skin prick testing, along with a previous history of reaction after ingesting peanuts.

Peanut allergy was present in 159 of the 519 (31%) patients. More males tended to have peanut allergy and 72% were white (16.4% African American, 15.7% Hispanic, and 7.5% Asian). In addition, 57% of the patients reported an allergy to one of the top 8 food allergens.

According to the poster presentation, the findings may be limited as the study was conducted at a single center and therefore may not be generalizable to the overall population of patients with EoE. However, the prevalence of patients with EoE with a concurrent diagnosis of peanut allergy suggests that the burden of peanut allergy in EoE should be considered in the development of future therapies. In addition, appropriate recommendations should be made to prevent accidental exposures that could lead to life-threatening reactions in these patients.

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Noor M, Anvari S, Olive AP, Kronisch LI, Davis CM. The prevalence of IgE-mediated peanut allergy in patients diagnosed with eosinophilic esophagitis. Presented at: American Academy of Allergy, Asthma & Immunology annual meeting 2019; February 22-25, 2019; San Francisco, CA. Abstract 420.