The following article is a part of conference coverage from the American College of Allergy, Asthma & Immunology 2021 Annual Scientific Meeting, being held virtually from November 4 to 8, 2021. The team at Pulmonology Advisor will be reporting on the latest news and research conducted by leading experts in the field. Check back for more from the ACAAI 2021 Annual Scientific Meeting.
Latino patients with asthma who developed COVID-19 experience a longer duration of asthma exacerbation post-COVID compared with non-Latino patients, according to research presented at the American College of Allergy, Asthma, and Immunology (ACAAI) Annual Scientific Meeting, held in New Orleans from November 4 to 8, 2021.
The study enrolled 174 patients with COVID-19 and history of asthma, including 23 Latino patients, 44 Black patients, and 111 White patients. These patients were evaluated at a single university medical center between February and April 2020. Patients were followed for a mean of 6.8 months. The investigators used logistic regression to compare post-infection asthma-related outcomes based on race/ethnicity. Analyses were adjusted for patient demographics, allergic rhinitis status, as well as inhaled corticosteroid uses.
Latino patients studied had a significantly higher odds of asthma exacerbation after COVID-19 compared with Black patients (odds ratio [OR], 4.6) and White patients (OR, 2.9) (P <.05). Latino patients also had a significantly greater duration of asthma exacerbation symptoms (mean, 3.2 weeks) vs non-Latino White patients (mean, 1.59 weeks) and non-Latino Black patients (mean, 1.4 weeks) (P =.021).
There was no difference between racial/ethnic groups in regard to the likelihood of initiating steroids for exacerbation relief or starting asthma step-up therapy. All groups had a comparable number of asthma-related provider visits (eg, clinic, emergency, or telehealth). The mean total visits per patient for exacerbation-related concerns was 1.9.
The investigators concluded that Latino patients “experienced longer durations of asthma exacerbation following COVID-19 infection compared to non-Latinos, indicative of increased susceptibility of asthmatic Latino patients to prolonged respiratory inflammation after SARS-COV and/or other respiratory viruses, even in light of equal care utilization, and warrants further investigation.”
Disclosure: Multiple authors declared affiliations with the pharmaceutical industry. Please refer to the original article for a full list of disclosures.
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Foster K, Jaswaney R, Moore D, Andy-Nweye A, Mahdavinia M. Latinos experience longer duration of uncontrolled asthma after COVID infection. Presented at: the ACAAI Annual Meeting; November 4-8, 2021. Abstract A032.