Women With COPD Have Worse QoL, Increased Symptom Burden
Women with COPD are more likely to be symptomatic and have greater odds of frequent, severe acute exacerbations.
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PM2.5-Related US Mortality Decreased From 2010 to 2017
During the same period, ozone-related mortality remained mainly unchanged.
High-Deductible Health Plans May Be Harmful in COPD
Individuals with high-deductible health plans are more likely to report forgoing care due to costs.
Early Neuromuscular Blockade Not Superior in ARDS With Ventilation
Mortality was similar in patients receiving continuous infusion of cisatracurium and those receiving lighter sedation targets.
Four Clinical Sepsis Phenotypes Identified
Phenotype distributions were similar in derivation and validation cohorts.
Dupilumab Lowers Exacerbation Rates in Late-Onset Asthma
Lung function improved at weeks 12 and 52 in patients with and without fixed airway obstruction.
Mometasone, Tiotropium Not Superior to Placebo in Mild Asthma
In patients with mild asthma with a low sputum eosinophil level, outcomes do not differ significantly for mometasone or tiotropium vs placebo.
Pulmonary Hypertension Survival Predicted by Cardiopulmonary Reserve Index
The cardiopulmonary reserve index is an effective predictor of prognosis in patients with pulmonary hypertension, particularly when pulmonary hypertension is caused by left heart disease.
Decreasing Ventilator-Associated Pneumonia in Level I Trauma Patients
Performing therapeutic bronchoscopy at the time of intensive care unit admission may decrease ventilator-associated pneumonia incidence in patients with level I trauma.
TB Treatment Monitoring: Molecular Bacterial Load Assay vs Standard Testing
Compared with standard of care tests and most clinical signs, the molecular bacterial load assay demonstrated higher sensitivity and more rapid turnaround times for monitoring tuberculosis treatment.
Improvements in PAH When Transitioned From PDEi to Riociguat
Patients with pulmonary arterial hypertension experienced a significant improvement in World Health Organization Functional Class when transitioned from a phosphodiesterase type 5 inhibitor to riociguat.
Budesonide-Formoterol Reliever Therapy Beats Albuterol for Prevention of Asthma Exacerbations
When used as needed, the combination of budesonide-formoterol was found to be superior to albuterol for the prevention of asthma exacerbations in patients with mild asthma.
Latent TB Detection: QuantiFERON-TB Gold Plus vs QuantiFERON-TB Gold In-Tube
Positive results with respect to the presence of latent tuberculosis infection in patients with renal failure were more consistent with the use of QuantiFERON-TB Gold Plus testing compared with the use of QuantiFERON-TB Gold In-Tube testing.
Improving Lung Function in COPD: Umeclidinium vs Salmeterol
Umeclidinium improved all lung function measures compared with salmeterol in patients with COPD who were naive to maintenance therapy or who were treated with a single maintenance bronchodilator.
Dry Powder Formulation of Treprostinil Appears Safe, Tolerable in PAH
Use of the dry powder formulation of treprostinil, known as LIQ861, has demonstrated safety and tolerability in patients with pulmonary arterial hypertension beyond 2 weeks.
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